PIPA586764

MST2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586764-Each-of-1 In Stock ₹ 44,705.10

PIPA586764 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MST2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STK3

Gene Alias

0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56274, 65189, 6788

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O54748, Q13188, Q9JI10

Gene Symbols

STK3

Immunogen

A synthetic peptide corresponding to residues in Human STK3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • STK3 (MST2) is a STE kinase family member that acts upstream of the MAP kinase signaling pathways, and is known to be activated by the proapoptotic stimuli staurosporine and FAS ligand
  • STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
  • It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
  • The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
  • Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
  • STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586764

--


Antigen:
MST2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK3

Gene Alias:
0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56274, 65189, 6788

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O54748, Q13188, Q9JI10

Gene Symbols:
STK3

Immunogen:
A synthetic peptide corresponding to residues in Human STK3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586765

--


Antigen:
TFF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TFF1

Gene Alias:
Bcei, breast cancer estrogen-inducible protein, breast cancer estrogen-inducible sequence, D21S21, gastrointestinal trefoil protein pS2, HP1.A, HPS2, PNR-2, polypeptide P1.A, Protein pS2, PS2, TFF1, Trefoil factor 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117270, 21784, 7031

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P04155, Q08423, Q63467

Gene Symbols:
TFF1

Immunogen:
A synthetic peptide corresponding to residues in Human TFF1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586766

--


Antigen:
IL22RA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL22RA2

Gene Alias:
CRF2-10, CRF2-S1, CRF2X, Cytokine receptor class-II member 10, Cytokine receptor family 2 member 10, cytokine receptor family II soluble 1, cytokine receptor family type 2, soluble 1, IL-22 receptor subunit alpha-2, IL22BP, IL-22BP, Il22ra2, IL-22RA2, IL-22R-alpha-2, interleukin 22 receptor subunit alpha 2, interleukin 22 receptor, alpha 2, interleukin 22-binding protein, interleukin-22 receptor subunit alpha-2, Interleukin-22-binding protein, UNQ5793/PRO19598/PRO19822, ZcytoR16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116379, 237310, 444986

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q7TNI4, Q80XF5, Q969J5

Gene Symbols:
IL22RA2

Immunogen:
A synthetic peptide corresponding to residues in Human IL-22Ralpha2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586767

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Antigen:
IFN alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNA2

Gene Alias:
alpha-2a interferon, Gm12597, ifa, Ifa1, Ifa2, IFL, IFN, IFN alpha, IFN alpha 1/13, IFN alpha 1b, IFN a, IFN1@, IFNA, IFNA@, IFNA1, IFNA13, Ifna15, Ifna2, IFNA2A, IFNA2B, IFNA2C, IFNA3, IFNA6, Ifnaa, IFNAalphaIFN-alpha-1/13, IFNalpha, IFN-alpha, IFN-alpha 1b, IFN-alpha1, IFN-alpha-1, IFN-alpha-1/13, IFN-alpha-2, IFN-alpha-6, IFN-alphaA, IFN-alphaD, IFN-gamma, IFNa, INFA2, interferon, interferon alpha, interferon alpha 1, Interferon alpha 13 (IFNA13), interferon alpha 15, interferon alpha 1b, interferon alpha 2, interferon alpha 2a, interferon alpha 2b, interferon alpha A, interferon alpha family gene 1, interferon alpha family, gene 2, Interferon alpha leukocyte (IFL), interferon alpha protein, interferon alpha-1, Interferon alpha1 (IFNA1), interferon alpha-1 precursor, interferon alpha-1/13, Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-2, Interferon alpha-A, Interferon alpha-D, Interferon alpha-D (IFN alphaD), interferon type A1/A2, interferon type A3, interferon, alpha 1, interferon, alpha 2, interferon-alpha, interferon-alpha 1, interferon-alpha1, interferon-alpha-6, leIF A, LeIF D, MGC138207, MGC138505, MGC138507, MuIFN-alpha-A, novel interferon alpha (Ifna) family member, OTTMUSG00000007655

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
111654, 15962, 15965, 242517, 3439, 3440

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P01562, P01563, P01572, P01573

Gene Symbols:
IFNA, IFNA1, Ifna15, IFNA2

Immunogen:
A synthetic peptide corresponding to residues in Human IFN-alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG