PIPA586465

c-Abl Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586465-Each-of-1 In Stock ₹ 44,705.10

PIPA586465 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

c-Abl

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ABL1

Gene Alias

Abelson murine leukemia oncogene, Abelson murine leukemia viral (v-abl) oncogene homolog 1, abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Abl, Abl 1 antib, ABL proto-oncogene 1, non-receptor tyrosine kinase, Abl1, ABL2, ABLL, AI325092, ARG, B30, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, E430008G22Rik, JTK7, p150, Proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, RP11-83J21.1, Tyrosine kinase ARG, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia oncogene 1, v-abl Abelson murine leukemia viral oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11350, 25, 311860

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P00519, P00520

Gene Symbols

ABL1

Immunogen

Synthetic peptide, corresponding to amino acids 851-900 of Human ABL1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA586077

--

Img

Thermo Scientific

PIPA586202

--

Img

Thermo Scientific

PIPA587378

--

Img

Thermo Scientific

PIPA586271

--

Img

Thermo Scientific

PIPA586079

--

Img

Thermo Scientific

PIPA586204

--

Img

Thermo Scientific

PIPA586230

--

Img

Thermo Scientific

PIPA586080

--

Description

  • The ABL1 proto-oncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response
  • Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns c-Abl into an oncogene
  • The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for c-Abl
  • In chronic myelogenous leukemia and a subset of acute lymphoblastic leukemias, the c-Abl proto oncogene undergoes a (9;22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome)
  • As the result of the fusion of c-Abl sequences from chromosome 9 to the Bcr gene on chromosome 22
  • The c-Abl oncogene was initially identified as the viral transforming gene of Abelson murine leukemia virus (A-MuLV)
  • c-ABL potentially regulates DNA repair by activating the proapoptotic pathway when the DNA damage is too severe to be repaired.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586465

--


Antigen:
c-Abl

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABL1

Gene Alias:
Abelson murine leukemia oncogene, Abelson murine leukemia viral (v-abl) oncogene homolog 1, abelson murine leukemia viral oncogene homolog 1, Abelson tyrosine-protein kinase 1, Abl, Abl 1 antib, ABL proto-oncogene 1, non-receptor tyrosine kinase, Abl1, ABL2, ABLL, AI325092, ARG, B30, bcr/abl, bcr/c-abl oncogene protein, c-ABL, c-abl oncogene 1, non-receptor tyrosine kinase, c-abl oncogene 1, receptor tyrosine kinase, c-ABL1, E430008G22Rik, JTK7, p150, Proto-oncogene c-Abl, proto-oncogene tyrosine-protein kinase ABL1, RP11-83J21.1, Tyrosine kinase ARG, tyrosine-protein kinase ABL1, v-abl, v-abl Abelson murine leukemia oncogene 1, v-abl Abelson murine leukemia viral oncogene 1, v-abl Abelson murine leukemia viral oncogene homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11350, 25, 311860

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P00519, P00520

Gene Symbols:
ABL1

Immunogen:
Synthetic peptide, corresponding to amino acids 851-900 of Human ABL1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586467

--


Antigen:
DNA Ligase I

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LIG1

Gene Alias:
AL033288, DNA ligase (ATP) 1, DNA ligase 1, DNA ligase I, LIG1, Lig-1, ligase 1, ligase I, DNA, ATP-dependent, LigI, MGC117397, MGC130025, polydeoxyribonucleotide synthase [ATP] 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3978

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P18858

Gene Symbols:
LIG1

Immunogen:
Synthetic peptide, corresponding to amino acids 110-160 of Human DNA Ligase I.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586468

--


Antigen:
Laminin alpha-4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LAMA4

Gene Alias:
CMD1JJ, LAMA3, LAMA4, LAMA4*-1, laminin [a]4, laminin alpha 4 chain, laminin subunit alpha 4, laminin subunit alpha-4, laminin, alpha 4, laminin-14 subunit alpha, Laminin-8 subunit alpha, laminin-9 subunit alpha, RGD1560062

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16775, 309816, 3910

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P97927, Q16363

Gene Symbols:
LAMA4

Immunogen:
Synthetic peptide, corresponding to amino acids 480-530 of Human Laminin alpha-4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586469

--


Antigen:
Bcl-W

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCL2L2

Gene Alias:
Apoptosis regulator Bcl-W, AW048834, BCL2 like 2, BCL2L2, BCL2-L-2, BCL2-like 2, BCL2-like 2 protein, Bcl-2-like protein 2, Bcl2-like protein 2, BCLW, BCL-W, BCL-WEL, BCL-WS, c98, Gtrgal2, Gtrosa41, Kiaa0271, PPP1R51, protein phosphatase 1, regulatory subunit 51

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12050, 599, 60434

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P70345, Q92843

Gene Symbols:
BCL2L2

Immunogen:
Synthetic peptide, corresponding to amino acids 120-165 of Human Bcl-w.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG