PIPA587367

A-Raf Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587367-Each-of-1 In Stock ₹ 44,705.10

PIPA587367 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

A-Raf

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ARAF

Gene Alias

1200013E08Rik, Araf, A-RAF, A-Raf proto-oncogene serine/threonine-protein kinase, A-Raf proto-oncogene, serine/threonine kinase, Araf1, A-raf-1, AW495444, Oncogene ARAF1, PKS, PKS2, Proto-oncogene A-Raf, proto-oncogene A-Raf-1, Proto-oncogene Pks, raf a, Raf related protein, RAFA1, raf-related oncogene, Ras-binding protein, Ras-binding protein DA-Raf, RP1-230G1.1, serine/threonine-protein kinase A-Raf, v-raf murine sarcoma 3611 viral oncogene homolog, v-raf murine sarcoma 3611 viral oncogene homolog 1, v-raf murine sarcoma 3611 viral oncogene-like protein, v-raf oncogene homolog 1 (murine sarcoma 3611 virus)

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

369

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.92 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P10398

Gene Symbols

ARAF

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 371-606 of human ARAF (NP_0016451)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: GFMTRPGFAI ITQWCEGSSL YHHLHVADTR FDMVQLIDVA RQTAQGMDYL HAKNIIHRDL KSNNIFLHEG LTVKIGDFGL ATVKTRWSGA QPLEQPSGSV LWMAAEVIRM QDPNPYSFQS DVYAYGVVLY ELMTGSLPYS HIGCRDQIIF MVGRGYLSPD LSKISSNCPK AMRRLLSDCL KFQREERPLF PQILATIELL QRSLPKIERS ASEPSLHRTQ ADELPACLLS AARLVP; Positive Samples: HeLa, Jurkat, HepG2 Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways
  • These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1
  • Raf-1 is a cytoplasmic protein with intrinsic serine/threonine activity
  • It is broadly expressed in nearly all cell lines tested to date and is the cellular homolog of v-Raf, the product of the transforming gene of the 3611 strain of murine sarcoma virus
  • The unregulated kinase activity of the v-Raf protein has been associated with transformation and mitogenesis while the activity of Raf-1 is normally suppressed by a regulatory N-terminal domain
  • A-Raf, a second member of the Raf gene family of serine/ threonine protein kinases, exhibits substantial homology to Raf-1 within the kinase domain of the two molecules, but less homology elsewhere
  • Expression of A-Raf is found at highest levels in urogenital tissues and kidney and at lowest level in brain tissue.

Compare Similar Items

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Img

Thermo Scientific

PIPA587367

--


Antigen:
A-Raf

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARAF

Gene Alias:
1200013E08Rik, Araf, A-RAF, A-Raf proto-oncogene serine/threonine-protein kinase, A-Raf proto-oncogene, serine/threonine kinase, Araf1, A-raf-1, AW495444, Oncogene ARAF1, PKS, PKS2, Proto-oncogene A-Raf, proto-oncogene A-Raf-1, Proto-oncogene Pks, raf a, Raf related protein, RAFA1, raf-related oncogene, Ras-binding protein, Ras-binding protein DA-Raf, RP1-230G1.1, serine/threonine-protein kinase A-Raf, v-raf murine sarcoma 3611 viral oncogene homolog, v-raf murine sarcoma 3611 viral oncogene homolog 1, v-raf murine sarcoma 3611 viral oncogene-like protein, v-raf oncogene homolog 1 (murine sarcoma 3611 virus)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
369

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.92 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P10398

Gene Symbols:
ARAF

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 371-606 of human ARAF (NP_0016451)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587368

--


Antigen:
RAD50

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD50

Gene Alias:
153 kDa protein, DNA repair protein RAD50, hRad50, hsRAD50, I79_004319, mRad50, Mrell, MRX complex DNA-binding subunit, N0872, NBSLD, Rad50, RAD50 2, RAD50 double strand break repair protein, RAD50 homolog (S. cerevisiae), RAD50 homolog, double strand break repair protein, RAD50 PEN, RAD502, RAD50-2, RAD50-3, Rad50l, YNL250W

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10111, 19360

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P70388, Q92878

Gene Symbols:
RAD50

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-270 of human Rad50 (NP_0057232)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587371

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Antigen:
BMI-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BMI1

Gene Alias:
AW546694, B lymphoma Mo-MLV insertion region 1, B lymphoma Mo-MLV insertion region 1 homolog, Bmi1, Bmi-1, BMI1 polycomb ring finger oncogene, BMI1 polycomb ring finger proto-oncogene, BMI1 proto-oncogene, polycomb ring finger, FLVI2/BMI1, flvi-2/bmi-1, murine leukemia viral (bmi-1) oncogene homolog, Pcgf4, Pcgf4 antibody, Polycomb complex protein BMI-1, polycomb group protein Bmi1, polycomb group ring finger 4, polycomb group RING finger protein 4, RING finger protein 51, RNF51, RP11-573G6.1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12151, 307151, 648

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
2.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P25916, P35226

Gene Symbols:
BMI1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Bmi1 (NP_0051714)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587373

--


Antigen:
Caspase 8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Casp8

Gene Alias:
ALPS2B, apoptosis-related cysteine peptidase, apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP8, CASP-8, caspase 8, caspase 8, apoptosis-related cysteine peptidase, caspase 8, apoptosis-related cysteine protease, Caspase8, caspase-8, Caspase-8 precursor, Caspase-8 subunit p10, Caspase-8 subunit p18, EC 3.4.22.61, FADD-homologous ICE/ced-3-like protease, FADD-like ICE, Fas-linked ICE-like protease, FLICE, FLJ17672, ICE8, ICE-like apoptotic protease 5, MACH, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein, MCH5, MGC78473, MORT1-associated ced-3 homolog, OTTHUMP00000163720, OTTHUMP00000165063, OTTHUMP00000206557, OTTHUMP00000206581

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12370, 64044, 841

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.99 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O89110, Q14790, Q9JHX4

Gene Symbols:
Casp8

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 376-479 of human Caspase 8 (NP_2035191)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG