PIPA586106

APAF1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586106-Each-of-1 In Stock ₹ 44,705.10

PIPA586106 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

APAF1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APAF1

Gene Alias

6230400I06Rik, APAF1, APAF-1, Apaf1l, apoptotic peptidase activating factor 1, apoptotic protease activating factor 1, apoptotic protease-activating factor 1, CED4, DKFZp781B1145, fog, forebrain overgrowth, KIAA0413, mKIAA0413

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11783, 317, 78963

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O14727, O88879, Q9EPV5

Gene Symbols

APAF1

Immunogen

Synthetic peptide, corresponding to amino acids 301-350 of Human Apaf-1-ALT.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • APAF1 gene encodes a cytoplasmic protein that initiates apoptosis
  • This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC)
  • Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome
  • The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form
  • Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis
  • Alternative splicing results in several transcript variants encoding different isoforms.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586106

--


Antigen:
APAF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APAF1

Gene Alias:
6230400I06Rik, APAF1, APAF-1, Apaf1l, apoptotic peptidase activating factor 1, apoptotic protease activating factor 1, apoptotic protease-activating factor 1, CED4, DKFZp781B1145, fog, forebrain overgrowth, KIAA0413, mKIAA0413

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11783, 317, 78963

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O14727, O88879, Q9EPV5

Gene Symbols:
APAF1

Immunogen:
Synthetic peptide, corresponding to amino acids 301-350 of Human Apaf-1-ALT.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586107

--


Antigen:
Protein APC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Apc

Gene Alias:
adenomatosis polyposis coli, adenomatosis polyposis coli tumor suppressor, adenomatous polyposis coli, adenomatous polyposis coli protein, AI047805, APC, APC, WNT signaling pathway regulator, AU020952, AW124434, BTPS2, CC1, Deleted in polyposis 2.5, DP2, DP2.5, DP3, FAP, FPC, GS, mAPC, Min, multiple intestinal neoplasia, PPP1R46, Protein APC, protein phosphatase 1, regulatory subunit 46, RATAPC, truncated adenomatosis polyposis coli, WNT signaling pathway regulator

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11789, 24205, 324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P25054, P70478, Q61315

Gene Symbols:
Apc

Immunogen:
Synthetic peptide, corresponding to the C-terminal of Human APC.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586108

--


Antigen:
ASK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K5

Gene Alias:
7420452D20Rik, apoptosis signal regulating kinase 1, apoptosis signal-regulating kinase 1, ASK, ASK 1, ASK1, ASK-1, EC 2.7.11.25, kinase ASK1, M3K5, MAP/ERK kinase kinase 5, Map3k5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, Mekk5, mitogen activated protein kinase kinase kinase 5, mitogen-activated protein kinase kinase kinase 5, RGD1306565, RP3-325F22.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
365057, 4217

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q99683

Gene Symbols:
MAP3K5

Immunogen:
Synthetic peptide, corresponding to amino acids 43-90 of Human ASK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586109

--


Antigen:
ASK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K5

Gene Alias:
7420452D20Rik, apoptosis signal regulating kinase 1, apoptosis signal-regulating kinase 1, ASK, ASK 1, ASK1, ASK-1, EC 2.7.11.25, kinase ASK1, M3K5, MAP/ERK kinase kinase 5, Map3k5, MAPK/ERK kinase kinase 5, MAPKKK5, MEK kinase 5, MEKK 5, Mekk5, mitogen activated protein kinase kinase kinase 5, mitogen-activated protein kinase kinase kinase 5, RGD1306565, RP3-325F22.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26408, 365057, 4217

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O35099, Q99683

Gene Symbols:
MAP3K5

Immunogen:
Synthetic peptide, corresponding to amino acids 924-978 of Human ASK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG