PIPA586189

NSE Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586189-Each-of-1 In Stock ₹ 44,705.10

PIPA586189 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NSE

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ENO2

Gene Alias

2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, AI837106, D6Ertd375e, Eno, ENO2, Eno-2, ENOG, Enolase 2, enolase 2 (gamma, neuronal), enolase 2, gamma neuronal, enolase 2, gamma, neuronal, epididymis secretory protein Li 279, gamma enolase, gamma-enolase, gamma-enolase-like, gamma-subunit of enolase, HEL-S-279, LOC100911625, Neural enolase, neuron specific enolase, neuron specific gamma enolase, Neuronal Enolase, neuronal enriched enolase, neurone-specific enolase, neuron-specific enolase, NSE, RNEN3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13807, 2026, 24334

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P07323, P09104, P17183

Gene Symbols

ENO2

Immunogen

Synthetic peptide, corresponding to amino acids 361-410 of Human NSE/Enolase.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Neuron specific enolase (NSE, ENO1, ENO2, ENO3) is an enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway, and the reverse reaction in gluconeogenesis
  • NSE has a high stability in biological fluids and can easily diffuse to the extracellular medium and cerebrospinal fluid (CSF) when neuronal membranes are injured.NSE is one of three mammalian enolases, which are also known as ENO1, ENO2, and ENO3 or alternately as enolase alpha, beta and gamma
  • The alpha-subunit is expressed in most tissues, the beta-subunit only in muscle, and the gamma-subunit is expressed primarily in neurons, in normal and in neoplastic neuroendocrine cells
  • Co-expression of NSE and chromogranin A is common in neuroendocrine neoplasms
  • Since neurons require a great deal of energy, they are very rich in glycolytic enzymes such a GAPDH and NSE
  • Antibodies to NSE protein are useful to identify neuronal cell bodies, developing neuronal lineage and neuroendocrine cells
  • Release of NSE from damaged neurons into CSF and blood has also been used as a biomarker of neuronal injury
  • NSE is used clinically as a sensitive and useful marker of neuronal damage in several neurological disorders including stroke, hypoxic brain damage, status epilepticus, Creutzfeldt-Jakob disease, and herpetic encephalitis
  • Further, NSE is found in elevated concentrations in plasma and certain neoplasias that include pediatric neuroblastoma and small cell lung cancer.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586189

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Antigen:
NSE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ENO2

Gene Alias:
2-phospho-D-glycerate hydrolyase, 2-phospho-D-glycerate hydro-lyase, AI837106, D6Ertd375e, Eno, ENO2, Eno-2, ENOG, Enolase 2, enolase 2 (gamma, neuronal), enolase 2, gamma neuronal, enolase 2, gamma, neuronal, epididymis secretory protein Li 279, gamma enolase, gamma-enolase, gamma-enolase-like, gamma-subunit of enolase, HEL-S-279, LOC100911625, Neural enolase, neuron specific enolase, neuron specific gamma enolase, Neuronal Enolase, neuronal enriched enolase, neurone-specific enolase, neuron-specific enolase, NSE, RNEN3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13807, 2026, 24334

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P07323, P09104, P17183

Gene Symbols:
ENO2

Immunogen:
Synthetic peptide, corresponding to amino acids 361-410 of Human NSE/Enolase.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586190

--


Antigen:
OCT1 (POU2F1)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POU2F1

Gene Alias:
2810482H01Rik, NF-A1, OCT1, oct-1, oct-1B, octamer binding protein 1, octamer-binding protein 1, Octamer-binding transcription factor 1, Octamer-binding transcription factor-1, Otf1, OTF-1, POU class 2 homeobox 1, POU domain, class 2, transcription factor 1, Pou2f1, ubiquitous transcription factor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171068, 18986, 5451

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P14859, P25425, P31503

Gene Symbols:
POU2F1

Immunogen:
Synthetic peptide, corresponding to amino acids 30-80 of Human Oct-1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586191

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Antigen:
OCT3/4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
POU5F1

Gene Alias:
2-Oct, 3-Oct, 4-Oct, cb197, chunp6868, DADB-104B20.2, etID49452.21, gp9, gp-9, HGNC:9221, homeobox protein, lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, MGC22487, NF-A3, Oct2, Oct-2, Oct2a, Oct2b, OCT3, Oct-3, Oct3/4, Oct-3/4, OCT4, Oct-4, Octamer-binding protein 2, octamer-binding protein 3, Octamer-binding protein 4, octamer-binding transcription factor 2, Octamer-binding transcription factor 3, OTF2, OTF-2, OTF3, Otf-3, Otf3g, Otf3-rs7, Otf4, Otf-4, OTTHUMP00000221150, OTTHUMP00000221151, POU class 2 homeobox 2, POU class 5 homeobox 1, POU class 5 homeobox 1 transcript variant OCT4B1, POU class 5 homeobox 1 transcript variant OCT4B2, POU class 5 homeobox 1 transcript variant OCT4B3, POU class 5 homeobox 1 transcript variant OCT4B4, POU class 5 homeobox 1 transcript variant OCT4B5, POU class 5 homeobox 1 transcript variant OCT4B6, POU domain class 5 transcription factor 1, POU domain gene 2, POU domain protein 2, POU domain transcription factor OCT4, POU domain, class 2, transcription factor 2, POU domain, class 5, transcription factor 1, POU domain, class 5, transcription factor 3, pou2, pou-2, POU2F2, Pou5f1, pou5f1 protein, pou5f3, POU-type homeodomain-containing DNA-binding protein, spg, spg/pou2, spiel-ohne-grenzen, spiel-ohne-grenzen/pou2, wu:fd18d06

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18999, 294562, 5460

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide, pH 7.2

Gene Accession No.:
P20263, Q01860

Gene Symbols:
POU5F1

Immunogen:
Synthetic peptide, corresponding to amino acids 200-250 of Human Oct-3/4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586192

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Antigen:
p16INK4a

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Alias:
Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P42771

Gene Symbols:
CDKN2A

Immunogen:
Synthetic peptide, corresponding to amino acids N-terminus of Human p16 INK4a.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG