PIPA586192
p16INK4a Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586192-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586192 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
p16INK4a
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CDKN2A
Gene Alias
Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1029
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P42771
Gene Symbols
CDKN2A
Immunogen
Synthetic peptide, corresponding to amino acids N-terminus of Human p16 INK4a.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This gene generates several transcript variants which differ in their first exons
- At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase
- The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants
- This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, the E3 ubiquitin-protein ligase MDM2, a protein responsible for the degradation of p53
- In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control
- This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.
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Antigen: p16INK4a
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1029
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P42771
Gene Symbols: CDKN2A
Immunogen: Synthetic peptide, corresponding to amino acids N-terminus of Human p16 INK4a.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
p16INK4a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDKN2A
Gene Alias:
Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1029
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P42771
Gene Symbols:
CDKN2A
Immunogen:
Synthetic peptide, corresponding to amino acids N-terminus of Human p16 INK4a.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: p14ARF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2A
Gene Alias: Alternative reading frame, ARF, ARF-INK4a, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, CDKN2A, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor sup
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1029, 12578, 25163
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P42771, Q64364, Q8QZZ9
Gene Symbols: CDKN2A
Immunogen: Synthetic peptide, corresponding to amino acids 65-121 of Human p19 ARF.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
p14ARF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDKN2A
Gene Alias:
Alternative reading frame, ARF, ARF-INK4a, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, CDKN2A, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor sup
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1029, 12578, 25163
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P42771, Q64364, Q8QZZ9
Gene Symbols:
CDKN2A
Immunogen:
Synthetic peptide, corresponding to amino acids 65-121 of Human p19 ARF.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CDKN2C
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDKN2C
Gene Alias: C77269, CDK6 inhibitor p18, Cdkn2c, CDKN6, cyclin dependent kinase inhibitor 2C, cyclin-dependent inhibitor, cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, cyclin-dependent kinase 6 inhibitor p18, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), INK4c, p18, p18INK4c, p18-INK4c, p18-INK6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1031, 12580, 54238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P42773, Q60772
Gene Symbols: CDKN2C
Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human p18 INK4c.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CDKN2C
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDKN2C
Gene Alias:
C77269, CDK6 inhibitor p18, Cdkn2c, CDKN6, cyclin dependent kinase inhibitor 2C, cyclin-dependent inhibitor, cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, cyclin-dependent kinase 6 inhibitor p18, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), INK4c, p18, p18INK4c, p18-INK4c, p18-INK6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1031, 12580, 54238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P42773, Q60772
Gene Symbols:
CDKN2C
Immunogen:
Synthetic peptide, corresponding to amino acids 100-150 of Human p18 INK4c.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NBS1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NBN
Gene Alias: AT V1, AT V2, ATV, AT-V1, AT-V2, Cell cycle regulatory protein p95, FLJ10155, I79_012607, MGC87362, Nbn, NBS, NBS1, nibrin, Nijmegen breakage syndrome 1 (nibrin), Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome protein 1 homolog, OTTHUMP00000204088, P95, p95 protein of the MRE11/RAD50 complex, p95-NBS1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4683, 85482
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O60934, Q9JIL9
Gene Symbols: NBN
Immunogen: Synthetic peptide, corresponding to amino acids 311-360 of Human Nibrin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NBS1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NBN
Gene Alias:
AT V1, AT V2, ATV, AT-V1, AT-V2, Cell cycle regulatory protein p95, FLJ10155, I79_012607, MGC87362, Nbn, NBS, NBS1, nibrin, Nijmegen breakage syndrome 1 (nibrin), Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome protein 1 homolog, OTTHUMP00000204088, P95, p95 protein of the MRE11/RAD50 complex, p95-NBS1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4683, 85482
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O60934, Q9JIL9
Gene Symbols:
NBN
Immunogen:
Synthetic peptide, corresponding to amino acids 311-360 of Human Nibrin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG