PIPA586193

p14ARF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586193-Each-of-1 In Stock ₹ 44,705.10

PIPA586193 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

p14ARF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDKN2A

Gene Alias

Alternative reading frame, ARF, ARF-INK4a, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, CDKN2A, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor sup

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

1029, 12578, 25163

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P42771, Q64364, Q8QZZ9

Gene Symbols

CDKN2A

Immunogen

Synthetic peptide, corresponding to amino acids 65-121 of Human p19 ARF.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA586192

--

Img

Thermo Scientific

PIPA586194

--

Img

Thermo Scientific

PIPA587334

--

Img

Thermo Scientific

PIPA586573

--

Img

Thermo Scientific

PIPA586611

--

Img

Thermo Scientific

PIPA586216

--

Img

Thermo Scientific

PIPA586678

--

Img

Thermo Scientific

PIPA586425

--

Description

  • Description The INK4a locus on chromosome 9p21 is frequently affected in human tumors
  • It encodes two structurally distinct tumor suppressor proteins, p16INK4a and the alternative reading frame protein, ARF (p14ARF in human and P19ARF in mouse)
  • These two proteins interact with the upstream proteins: retinoblastoma protein and p53 tumor suppressors, respectively
  • Each of these proteins has a role in the senescence of primary cells, activates pathways for cell cycle control and tumor suppression
  • The p14ARF (or P19ARF in mouse) proteins can induce both G1 and G2 phase arrest in a manner that depends on functional p53
  • The mouse and human ARF proteins have different functions in tumor suppression; this distinction may contribute to the different levels of tumor proneness of these species.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586193

--


Antigen:
p14ARF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Alias:
Alternative reading frame, ARF, ARF-INK4a, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, CDKN2A, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor sup

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1029, 12578, 25163

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P42771, Q64364, Q8QZZ9

Gene Symbols:
CDKN2A

Immunogen:
Synthetic peptide, corresponding to amino acids 65-121 of Human p19 ARF.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586194

--


Antigen:
CDKN2C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN2C

Gene Alias:
C77269, CDK6 inhibitor p18, Cdkn2c, CDKN6, cyclin dependent kinase inhibitor 2C, cyclin-dependent inhibitor, cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, cyclin-dependent kinase 6 inhibitor p18, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4), INK4c, p18, p18INK4c, p18-INK4c, p18-INK6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1031, 12580, 54238

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P42773, Q60772

Gene Symbols:
CDKN2C

Immunogen:
Synthetic peptide, corresponding to amino acids 100-150 of Human p18 INK4c.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586196

--


Antigen:
NBS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NBN

Gene Alias:
AT V1, AT V2, ATV, AT-V1, AT-V2, Cell cycle regulatory protein p95, FLJ10155, I79_012607, MGC87362, Nbn, NBS, NBS1, nibrin, Nijmegen breakage syndrome 1 (nibrin), Nijmegen breakage syndrome protein 1, Nijmegen breakage syndrome protein 1 homolog, OTTHUMP00000204088, P95, p95 protein of the MRE11/RAD50 complex, p95-NBS1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4683, 85482

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O60934, Q9JIL9

Gene Symbols:
NBN

Immunogen:
Synthetic peptide, corresponding to amino acids 311-360 of Human Nibrin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586197

--


Antigen:
PDGF-B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDGFB

Gene Alias:
becaplermin, c-sis, I79_017626, IBGC5, PDGF, pdgf protein, PDGF subunit B, PDGF, B chain, PDGF2, PDGF-2, Pdgfb, PDGF-B, platelet derived growth factor subunit B, platelet derived growth factor, B polypeptide, platelet-derived growth factor 2, platelet-derived growth factor B, platelet-derived growth factor B chain, platelet-derived growth factor B subunit, platelet-derived growth factor beta, platelet-derived growth factor beta isoform 1, preproprotein, platelet-derived growth factor beta polypeptide, platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog), Platelet-derived growth factor subunit B, platelet-derived growth factor, beta polypeptide (oncogene SIS), Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis), proto-oncogene c-Sis, Sis, SSV, v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18591, 24628, 5155

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P01127, P31240, Q05028

Gene Symbols:
PDGFB

Immunogen:
Synthetic peptide, corresponding to amino acids 21-70 of Human PDGF-B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG