PIPA586234
POLR2A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586234-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586234 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
POLR2A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLR2A
Gene Alias
220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20020, 363633, 5430
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P08775, P24928
Gene Symbols
POLR2A
Immunogen
Synthetic peptide, corresponding to amino acids 1580-1630 of Human Rpb1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DNA-directed RNA polymerase II subunit RPB1 (POLR1A) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
- POLR1A is the largest subunit and is a catalytic component of RNA polymerase II which synthesizes mRNA precurors and many functional non-coding RNAs
- It also forms the polymerase active center together with the second largest subunit
- Pol II is the central component of the basal RNA polymerase II transcription machinery
- It is composed of mobile elements that move relative to each other
- RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft, and the jaws that are though to grab the incoming DNA template
- At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II
- A bridging helix emanates from RPB1 and crosses the cleft near the catalytic stie and is through to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition
- During transcription elongation, Pol II moves on the template as the transcript elongates
- Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II's largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination, and mRNA processing
- Regulation of gene expression levels depends on the balance between methylation and acetylation levelts of the CTD-lysines.
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Antigen: POLR2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLR2A
Gene Alias: 220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20020, 363633, 5430
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P08775, P24928
Gene Symbols: POLR2A
Immunogen: Synthetic peptide, corresponding to amino acids 1580-1630 of Human Rpb1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
POLR2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLR2A
Gene Alias:
220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20020, 363633, 5430
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P08775, P24928
Gene Symbols:
POLR2A
Immunogen:
Synthetic peptide, corresponding to amino acids 1580-1630 of Human Rpb1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SGK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SGK1
Gene Alias: serine/threonine protein kinase SGK, serine/threonine-protein kinase Sgk1, serum and glucocorticoid-dependent protein kinase, serum/glucocorticoid regulated kinase 1, serum/glucocorticoid-regulated kinase 1, Sgk, SGK1, Sgk1 variant i3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20393, 29517, 6446
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O00141, Q06226, Q9WVC6
Gene Symbols: SGK1
Immunogen: Synthetic peptide, corresponding to amino acids 391-440 of Human SGK1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SGK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SGK1
Gene Alias:
serine/threonine protein kinase SGK, serine/threonine-protein kinase Sgk1, serum and glucocorticoid-dependent protein kinase, serum/glucocorticoid regulated kinase 1, serum/glucocorticoid-regulated kinase 1, Sgk, SGK1, Sgk1 variant i3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20393, 29517, 6446
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O00141, Q06226, Q9WVC6
Gene Symbols:
SGK1
Immunogen:
Synthetic peptide, corresponding to amino acids 391-440 of Human SGK1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SHC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SHC1
Gene Alias: FLJ26504, OTTHUMP00000035472, p66, P66shc, RP11-307C12.1, SH2 domain protein C1, SHC, SHC (Src homology 2 domain containing) transforming protein 1, SHC (Src homology 2 domain-containing) transforming protein 1, SHC adaptor protein 1, SHC1, SHCA, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A, src homology 2 domain-containing transforming protein C1, src homology 2 domain-containing-transforming protein C1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20416, 6464, 85385
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P29353, P98083, Q5M824
Gene Symbols: SHC1
Immunogen: Synthetic peptide, corresponding to amino acids 390-440 of Human Shc.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SHC1
Gene Alias:
FLJ26504, OTTHUMP00000035472, p66, P66shc, RP11-307C12.1, SH2 domain protein C1, SHC, SHC (Src homology 2 domain containing) transforming protein 1, SHC (Src homology 2 domain-containing) transforming protein 1, SHC adaptor protein 1, SHC1, SHCA, SHC-transforming protein 1, SHC-transforming protein 3, SHC-transforming protein A, src homology 2 domain-containing transforming protein C1, src homology 2 domain-containing-transforming protein C1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20416, 6464, 85385
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P29353, P98083, Q5M824
Gene Symbols:
SHC1
Immunogen:
Synthetic peptide, corresponding to amino acids 390-440 of Human Shc.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SHP-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTPN6
Gene Alias: 70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116689, 15170, 5777
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P29350, P29351, P81718
Gene Symbols: PTPN6
Immunogen: Synthetic peptide, corresponding to amino acids 500-550 of Human SHP-1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SHP-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTPN6
Gene Alias:
70Z-SHP, EC 3.1.3.48, hcp, Hcph, hematopoietic cell phosphatase, hematopoietic cell protein-tyrosine phosphatase, HPTP1C, me, motheaten, protein tyrosine phosphatase, non-receptor type 6, protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTN6, Ptp1C, PTP-1C, Ptph6, PTPN6, PTPTY-42, SH2 phosphatase 1, SHP1, Shp-1, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116689, 15170, 5777
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P29350, P29351, P81718
Gene Symbols:
PTPN6
Immunogen:
Synthetic peptide, corresponding to amino acids 500-550 of Human SHP-1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG