PIPA586326

JAK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586326-Each-of-1 In Stock ₹ 45,218.46

PIPA586326 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

JAK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK3

Gene Alias

Breast-JAK3, fae, JAK3, JAK-3, JAK3_HUMAN, JAK3B, JAKL, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3 protein-tyrosine kinase, Janus kinase 3, protein-tyrosine kinase, L JAK, Leukocyte janus kinase, LJAK, L-JAK, RATJAK3, Tyrosine-protein kinase JAK3, wil

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16453, 25326, 3718

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P52333, Q62137, Q63272

Gene Symbols

JAK3

Immunogen

Synthetic peptide, corresponding to amino acids 750-800 of Human JAK3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA587500

--

Img

Thermo Scientific

PIPA587323

--

Img

Thermo Scientific

PIPA586682

--

Img

Thermo Scientific

PIPA586076

--

Img

Thermo Scientific

PIPA586374

--

Img

Thermo Scientific

PIPA586180

--

Img

Thermo Scientific

PIPA586641

--

Img

Thermo Scientific

PIPA587497

--

Description

  • Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family
  • JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586326

--


Antigen:
JAK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK3

Gene Alias:
Breast-JAK3, fae, JAK3, JAK-3, JAK3_HUMAN, JAK3B, JAKL, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3 protein-tyrosine kinase, Janus kinase 3, protein-tyrosine kinase, L JAK, Leukocyte janus kinase, LJAK, L-JAK, RATJAK3, Tyrosine-protein kinase JAK3, wil

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16453, 25326, 3718

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P52333, Q62137, Q63272

Gene Symbols:
JAK3

Immunogen:
Synthetic peptide, corresponding to amino acids 750-800 of Human JAK3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586327

--


Antigen:
Moesin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSN

Gene Alias:
C78546, epididymis luminal protein 70, HEL70, Membrane-organizing extension spike protein, MGC137877 protein, moesin, MSN

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17698, 4478, 81521

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O35763, P26038, P26041

Gene Symbols:
MSN

Immunogen:
Synthetic peptide, corresponding to amino acids 520-570 of Human Moesin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586328

--


Antigen:
p130Cas

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCAR1

Gene Alias:
AI385681, BCA1, Bcar1, BCAR1 scaffold protein, Cas family member, BCAR1, Cas family scaffold protein, BCAR1, Cas family scaffolding protein, breast cancer anti-estrogen resistance 1, breast cancer anti-estrogen resistance protein 1, Cas, Cas scaffolding protein family member 1, CAS1, CASS1, CRKAS, CRK-associated substrate, Crk-associated substrate p130Cas, OTTHUMP00000174941, p130 Cas, P130CAS, p130Cas (pTyr410), p130Cas (pY410), p130Cas phospho, phospho p130Cas, v-crk-associated tyrosine kinase substrate

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12927, 25414, 9564

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P56945, Q61140, Q63767

Gene Symbols:
BCAR1

Immunogen:
Synthetic peptide, corresponding to amino acids 140-180 of Human p130 Cas.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586329

--


Antigen:
RPA2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rpa2

Gene Alias:
30-kDa protein, AA409079, AI325195, AU020965, HSSB, hypothetical protein, I79_004200, p32, p32-subunit of replication protein A, p34, REPA2, Replication factor A protein 2, replication protein A 32 kDa subunit, Replication protein A 32kDa subunit, Replication protein A 34 kDa subunit, Replication protein A 34kDa subunit, replication protein A2, replication protein A2, 32kDa, replication protein A4, RFA, RF-A protein 2, Rf-A2, RP21C, RP4-547C9.3, RP-A p32, RP-A p34, RPA2, RPA32, RPA34, RPA4, RpLP1, RpP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19891, 6118

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P15927, Q62193

Gene Symbols:
Rpa2

Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human RPA2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG