PIPA587500

JAK3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587500-Each-of-1 In Stock ₹ 44,191.74

PIPA587500 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

JAK3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

JAK3

Gene Alias

Breast-JAK3, fae, JAK3, JAK-3, JAK3_HUMAN, JAK3B, JAKL, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3 protein-tyrosine kinase, Janus kinase 3, protein-tyrosine kinase, L JAK, Leukocyte janus kinase, LJAK, L-JAK, RATJAK3, Tyrosine-protein kinase JAK3, wil

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3718

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

2.13 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P52333

Gene Symbols

JAK3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-530 of JAK3 (NP_0002062)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: RLTTDSQHFF CKEVAPPRLL EEVAEQCHGP ITLDFAINKL KTGGSRPGSY VLRRSPQDFD SFLLTVCVQN PLGPDYKGCL IRRSPTGTFL LVGLSRPHSS LRELLATCWD GGLHVDGVAV TLTSCCIPRP KEKSNLIVVQ RGHSPPTSSL VQPQSQYQLS QMTFHKIPAD SLEWHENLGH G Positive Samples: U-87MG; Cellular Location: Cytoplasm, Endomembrane system, Peripheral membrane protein Janus kinase 3 (JAK3) phosphorylates members of the STAT (signal transduction and activators of transcription) family
  • JAK3 is predominantly expressed in immune cells and transduces a signal in response to activation of interleukin receptors
  • In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
  • The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
  • Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
  • JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
  • However, active JAK1 may be required for complex responses
  • Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex.

Compare Similar Items

Show Difference

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PIPA587500

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Antigen:
JAK3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK3

Gene Alias:
Breast-JAK3, fae, JAK3, JAK-3, JAK3_HUMAN, JAK3B, JAKL, Janus kinase 3, Janus kinase 3 (a protein tyrosine kinase, leukocyte), Janus kinase 3 protein-tyrosine kinase, Janus kinase 3, protein-tyrosine kinase, L JAK, Leukocyte janus kinase, LJAK, L-JAK, RATJAK3, Tyrosine-protein kinase JAK3, wil

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3718

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P52333

Gene Symbols:
JAK3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-530 of JAK3 (NP_0002062)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA587501

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Antigen:
ErbB4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB4

Gene Alias:
4ICD, ALS19, avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4, avian erythroblastosis oncogene B 4, c-erbB-4, erb-b2 receptor tyrosine kinase 4, Erbb4, ERBB4 intracellular domain, ERBB4 transcript variant I12DEL, ERBB4 transcript variant I20DEL, Her4, human epidermal growth factor receptor 4, Mer4, OTTHUMP00000209432, p180erbB4, proto-oncogene-like protein c-ErbB-4, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-4, s80HER4, Tyro-2, Tyrosine kinase-type cell surface receptor HER4, v-erb-a erythroblastic leukemia viral oncogene homolog 4, v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), v-erb-b2 avian erythroblastic leukemia viral oncogene 4, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
59323

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.45 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q62956

Gene Symbols:
ERBB4

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human ErbB4/HER4 (NP_0052261)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587504

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Antigen:
ELK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ELK1

Gene Alias:
ELK 1, ELK1, Elk-1, ELK1, ETS transcription factor, ELK1, member of ETS oncogene family, ETS domain-containing protein Elk-1, ETS transcription factor ELK1, ETS-like gene 1, Oncogene Elk1, tyrosine kinase (ELK1) oncogene

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13712, 2002, 314436

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.67 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
A4GTP4, P19419, P41969

Gene Symbols:
ELK1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 201-297 of human ELK1 (NP_0052202)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587505

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Antigen:
CDX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDX2

Gene Alias:
caudal type homeo box 2, caudal type homeo box transcription factor 2, caudal type homeobox 2, caudal type homeobox transcription factor 2, caudal-type homeobox protein 2, CDX2, Cdx-2, CDX2/AS, CDX3, CDX-3, HGNC:1806, homeobox protein CDX-2, homeobox protein miniCDX2, homeobox transcription factor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1045, 12591, 66019

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P43241, Q99626

Gene Symbols:
CDX2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CDX2 (NP_0012563)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG