PIPA586497
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586497-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA586497 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
Synthetic peptide, corresponding to amino acids 20-70 of Human HSP 70.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human HSP 70.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Synthetic peptide, corresponding to amino acids 20-70 of Human HSP 70.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: hnRNP M
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HNRNPM
Gene Alias: 2610023M21Rik, AA409009, CEA receptor, CEAR, heterogeneous nuclear ribonucleoprotein M, heterogenous nuclear ribonucleoprotein M4, hnRNA-binding protein M4, hnRNP M, HNRNPM, HNRNPM4, Hnrpm, Hnrpm4, HTGR1, LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein M, M4 protein, mKIAA4193, N-acetylglucosamine receptor 1, NAGR1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116655, 4670, 76936
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P52272, Q62826, Q9D0E1
Gene Symbols: HNRNPM
Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human hnRNP M.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
hnRNP M
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HNRNPM
Gene Alias:
2610023M21Rik, AA409009, CEA receptor, CEAR, heterogeneous nuclear ribonucleoprotein M, heterogenous nuclear ribonucleoprotein M4, hnRNA-binding protein M4, hnRNP M, HNRNPM, HNRNPM4, Hnrpm, Hnrpm4, HTGR1, LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein M, M4 protein, mKIAA4193, N-acetylglucosamine receptor 1, NAGR1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116655, 4670, 76936
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P52272, Q62826, Q9D0E1
Gene Symbols:
HNRNPM
Immunogen:
Synthetic peptide, corresponding to amino acids 20-70 of Human hnRNP M.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CHRM2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHRM2
Gene Alias: 7TM receptor, acetylcholine receptor, acetylcholine receptor, muscarinic 2, AChR M2, AChR-M2, Acm2, cardiac muscarinic acetylcholine receptor, cholinergic receptor, cholinergic receptor muscarinic 2, cholinergic receptor, muscarinic 2, cholinergic receptor, muscarinic 2, cardiac, cholinergic receptor, muscarinic 2, isoform a, Chrm2, Chrm-2, FLJ43243, HM2, M2, M2 muscarinic acetylcholine receptor, m2AChR, M2-mAChR, MGC120006, MGC120007, muscarinic acetylcholine receptor 2, muscarinic acetylcholine receptor m2, muscarinic M2 receptor, muscarinic receptor m2, unnamed protein product
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1129, 243764, 81645
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P08172, P10980, Q9ERZ4
Gene Symbols: CHRM2
Immunogen: Synthetic peptide, corresponding to amino acids 191-240 of Human mAChR M2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CHRM2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHRM2
Gene Alias:
7TM receptor, acetylcholine receptor, acetylcholine receptor, muscarinic 2, AChR M2, AChR-M2, Acm2, cardiac muscarinic acetylcholine receptor, cholinergic receptor, cholinergic receptor muscarinic 2, cholinergic receptor, muscarinic 2, cholinergic receptor, muscarinic 2, cardiac, cholinergic receptor, muscarinic 2, isoform a, Chrm2, Chrm-2, FLJ43243, HM2, M2, M2 muscarinic acetylcholine receptor, m2AChR, M2-mAChR, MGC120006, MGC120007, muscarinic acetylcholine receptor 2, muscarinic acetylcholine receptor m2, muscarinic M2 receptor, muscarinic receptor m2, unnamed protein product
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1129, 243764, 81645
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P08172, P10980, Q9ERZ4
Gene Symbols:
CHRM2
Immunogen:
Synthetic peptide, corresponding to amino acids 191-240 of Human mAChR M2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PIK3R2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PIK3R2
Gene Alias: MPPH, MPPH1, p85, P85B, p85beta, p85-BETA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, phosphatidylinositol 3-kinase regulartory subunit polypeptide 2, phosphatidylinositol 3-kinase regulatory subunit beta, phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta), phosphoinositide-3-kinase regulatory subunit 2, phosphoinositide-3-kinase regulatory subunit beta, phosphoinositide-3-kinase, regulatory subunit 2 (beta), phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta), phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta), PI3K, PI3K regulatory subunit beta, PI3-kinase p85 subunit beta, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PIK3R2, ptdIns-3-kinase p85-beta, ptdIns-3-kinase regulatory subunit beta, ptdIns-3-kinase regulatory subunit p85-beta
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18709, 29741, 5296
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O00459, O08908, Q63788
Gene Symbols: PIK3R2
Immunogen: Synthetic peptide, corresponding to amino acids 471-520 of Human PI3K p85beta.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PIK3R2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PIK3R2
Gene Alias:
MPPH, MPPH1, p85, P85B, p85beta, p85-BETA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, phosphatidylinositol 3-kinase regulartory subunit polypeptide 2, phosphatidylinositol 3-kinase regulatory subunit beta, phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta), phosphoinositide-3-kinase regulatory subunit 2, phosphoinositide-3-kinase regulatory subunit beta, phosphoinositide-3-kinase, regulatory subunit 2 (beta), phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta), phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta), PI3K, PI3K regulatory subunit beta, PI3-kinase p85 subunit beta, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PIK3R2, ptdIns-3-kinase p85-beta, ptdIns-3-kinase regulatory subunit beta, ptdIns-3-kinase regulatory subunit p85-beta
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18709, 29741, 5296
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O00459, O08908, Q63788
Gene Symbols:
PIK3R2
Immunogen:
Synthetic peptide, corresponding to amino acids 471-520 of Human PI3K p85beta.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG