PIPA586497
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586497-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586497 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
Synthetic peptide, corresponding to amino acids 20-70 of Human HSP 70.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human HSP 70.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 0.05% sodium azide, pH 7.2
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Synthetic peptide, corresponding to amino acids 20-70 of Human HSP 70.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: hnRNP M
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HNRNPM
Gene Alias: 2610023M21Rik, AA409009, CEA receptor, CEAR, heterogeneous nuclear ribonucleoprotein M, heterogenous nuclear ribonucleoprotein M4, hnRNA-binding protein M4, hnRNP M, HNRNPM, HNRNPM4, Hnrpm, Hnrpm4, HTGR1, LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein M, M4 protein, mKIAA4193, N-acetylglucosamine receptor 1, NAGR1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116655, 4670, 76936
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P52272, Q62826, Q9D0E1
Gene Symbols: HNRNPM
Immunogen: Synthetic peptide, corresponding to amino acids 20-70 of Human hnRNP M.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
hnRNP M
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HNRNPM
Gene Alias:
2610023M21Rik, AA409009, CEA receptor, CEAR, heterogeneous nuclear ribonucleoprotein M, heterogenous nuclear ribonucleoprotein M4, hnRNA-binding protein M4, hnRNP M, HNRNPM, HNRNPM4, Hnrpm, Hnrpm4, HTGR1, LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein M, M4 protein, mKIAA4193, N-acetylglucosamine receptor 1, NAGR1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116655, 4670, 76936
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P52272, Q62826, Q9D0E1
Gene Symbols:
HNRNPM
Immunogen:
Synthetic peptide, corresponding to amino acids 20-70 of Human hnRNP M.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CHRM2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CHRM2
Gene Alias: 7TM receptor, acetylcholine receptor, acetylcholine receptor, muscarinic 2, AChR M2, AChR-M2, Acm2, cardiac muscarinic acetylcholine receptor, cholinergic receptor, cholinergic receptor muscarinic 2, cholinergic receptor, muscarinic 2, cholinergic receptor, muscarinic 2, cardiac, cholinergic receptor, muscarinic 2, isoform a, Chrm2, Chrm-2, FLJ43243, HM2, M2, M2 muscarinic acetylcholine receptor, m2AChR, M2-mAChR, MGC120006, MGC120007, muscarinic acetylcholine receptor 2, muscarinic acetylcholine receptor m2, muscarinic M2 receptor, muscarinic receptor m2, unnamed protein product
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1129, 243764, 81645
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P08172, P10980, Q9ERZ4
Gene Symbols: CHRM2
Immunogen: Synthetic peptide, corresponding to amino acids 191-240 of Human mAChR M2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CHRM2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CHRM2
Gene Alias:
7TM receptor, acetylcholine receptor, acetylcholine receptor, muscarinic 2, AChR M2, AChR-M2, Acm2, cardiac muscarinic acetylcholine receptor, cholinergic receptor, cholinergic receptor muscarinic 2, cholinergic receptor, muscarinic 2, cholinergic receptor, muscarinic 2, cardiac, cholinergic receptor, muscarinic 2, isoform a, Chrm2, Chrm-2, FLJ43243, HM2, M2, M2 muscarinic acetylcholine receptor, m2AChR, M2-mAChR, MGC120006, MGC120007, muscarinic acetylcholine receptor 2, muscarinic acetylcholine receptor m2, muscarinic M2 receptor, muscarinic receptor m2, unnamed protein product
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1129, 243764, 81645
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P08172, P10980, Q9ERZ4
Gene Symbols:
CHRM2
Immunogen:
Synthetic peptide, corresponding to amino acids 191-240 of Human mAChR M2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PIK3R2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PIK3R2
Gene Alias: MPPH, MPPH1, p85, P85B, p85beta, p85-BETA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, phosphatidylinositol 3-kinase regulartory subunit polypeptide 2, phosphatidylinositol 3-kinase regulatory subunit beta, phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta), phosphoinositide-3-kinase regulatory subunit 2, phosphoinositide-3-kinase regulatory subunit beta, phosphoinositide-3-kinase, regulatory subunit 2 (beta), phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta), phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta), PI3K, PI3K regulatory subunit beta, PI3-kinase p85 subunit beta, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PIK3R2, ptdIns-3-kinase p85-beta, ptdIns-3-kinase regulatory subunit beta, ptdIns-3-kinase regulatory subunit p85-beta
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18709, 29741, 5296
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O00459, O08908, Q63788
Gene Symbols: PIK3R2
Immunogen: Synthetic peptide, corresponding to amino acids 471-520 of Human PI3K p85beta.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PIK3R2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PIK3R2
Gene Alias:
MPPH, MPPH1, p85, P85B, p85beta, p85-BETA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta, phosphatidylinositol 3-kinase regulartory subunit polypeptide 2, phosphatidylinositol 3-kinase regulatory subunit beta, phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta), phosphoinositide-3-kinase regulatory subunit 2, phosphoinositide-3-kinase regulatory subunit beta, phosphoinositide-3-kinase, regulatory subunit 2 (beta), phosphoinositide-3-kinase, regulatory subunit 2 (p85 beta), phosphoinositide-3-kinase, regulatory subunit, polypeptide 2 (p85 beta), PI3K, PI3K regulatory subunit beta, PI3-kinase p85 subunit beta, PI3-kinase regulatory subunit beta, PI3-kinase subunit p85-beta, PIK3R2, ptdIns-3-kinase p85-beta, ptdIns-3-kinase regulatory subunit beta, ptdIns-3-kinase regulatory subunit p85-beta
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18709, 29741, 5296
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O00459, O08908, Q63788
Gene Symbols:
PIK3R2
Immunogen:
Synthetic peptide, corresponding to amino acids 471-520 of Human PI3K p85beta.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG