PIPA586680
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586680-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586680 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AMPK alpha-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Prkaa1
Gene Alias: 5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 105787, 5562, 65248
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P54645, Q13131, Q5EG47
Gene Symbols: Prkaa1
Immunogen: Synthetic peptide, corresponding to amino acids 470-520 of Human AMPKalpha1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AMPK alpha-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Prkaa1
Gene Alias:
5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
105787, 5562, 65248
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P54645, Q13131, Q5EG47
Gene Symbols:
Prkaa1
Immunogen:
Synthetic peptide, corresponding to amino acids 470-520 of Human AMPKalpha1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: JAK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JAK1
Gene Alias: AA960307, BAP004, C130039L05Rik, EC 2.7.10.2, Jak1, JAK-1, JAK1A, JAK1B, Janus kinase 1, Janus protein tyrosine kinase 1, JTK3, kinase Jak1, Tyrosine-protein kinase JAK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16451, 3716, 84598
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P23458, P52332
Gene Symbols: JAK1
Immunogen: Residues 980-1030 of human JAK1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
JAK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JAK1
Gene Alias:
AA960307, BAP004, C130039L05Rik, EC 2.7.10.2, Jak1, JAK-1, JAK1A, JAK1B, Janus kinase 1, Janus protein tyrosine kinase 1, JTK3, kinase Jak1, Tyrosine-protein kinase JAK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16451, 3716, 84598
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P23458, P52332
Gene Symbols:
JAK1
Immunogen:
Residues 980-1030 of human JAK1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HSD11B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hsd11b1
Gene Alias: 11 beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD type 1, 11-beta-HSD1, 11beta-HSD1, 11beta-HSD-1, 11beta-HSD1A, 11-beta-hydroxysteroid dehydrogenase, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A), cortocosteroid 11-beta dehydrogenase, CORTRD2, HDL, HSD11, HSD11B, Hsd11b1, HSD11L, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid dehydrogenase, 11 beta type 1, LRRGT00065, MGC13539, OTTHUMP00000034650, SDR26C1, short chain dehydrogenase/reductase family 26C member 1, short chain dehydrogenase/reductase family 26C, member 1, short-chain reductase, short-chain reductase/dehydrogenase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15483, 25116, 3290
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P16232, P28845, P50172
Gene Symbols: Hsd11b1
Immunogen: Synthetic peptide, corresponding to amino acids 43-88 of Human HSD11B1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HSD11B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hsd11b1
Gene Alias:
11 beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD type 1, 11-beta-HSD1, 11beta-HSD1, 11beta-HSD-1, 11beta-HSD1A, 11-beta-hydroxysteroid dehydrogenase, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A), cortocosteroid 11-beta dehydrogenase, CORTRD2, HDL, HSD11, HSD11B, Hsd11b1, HSD11L, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid dehydrogenase, 11 beta type 1, LRRGT00065, MGC13539, OTTHUMP00000034650, SDR26C1, short chain dehydrogenase/reductase family 26C member 1, short chain dehydrogenase/reductase family 26C, member 1, short-chain reductase, short-chain reductase/dehydrogenase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15483, 25116, 3290
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P16232, P28845, P50172
Gene Symbols:
Hsd11b1
Immunogen:
Synthetic peptide, corresponding to amino acids 43-88 of Human HSD11B1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG