PIPA586680
Histone H2A.X Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586680-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA586680 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
Histone H2A.X
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Description Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AMPK alpha-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Prkaa1
Gene Alias: 5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 105787, 5562, 65248
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P54645, Q13131, Q5EG47
Gene Symbols: Prkaa1
Immunogen: Synthetic peptide, corresponding to amino acids 470-520 of Human AMPKalpha1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AMPK alpha-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Prkaa1
Gene Alias:
5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
105787, 5562, 65248
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P54645, Q13131, Q5EG47
Gene Symbols:
Prkaa1
Immunogen:
Synthetic peptide, corresponding to amino acids 470-520 of Human AMPKalpha1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: JAK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: JAK1
Gene Alias: AA960307, BAP004, C130039L05Rik, EC 2.7.10.2, Jak1, JAK-1, JAK1A, JAK1B, Janus kinase 1, Janus protein tyrosine kinase 1, JTK3, kinase Jak1, Tyrosine-protein kinase JAK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16451, 3716, 84598
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P23458, P52332
Gene Symbols: JAK1
Immunogen: Residues 980-1030 of human JAK1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
JAK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
JAK1
Gene Alias:
AA960307, BAP004, C130039L05Rik, EC 2.7.10.2, Jak1, JAK-1, JAK1A, JAK1B, Janus kinase 1, Janus protein tyrosine kinase 1, JTK3, kinase Jak1, Tyrosine-protein kinase JAK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16451, 3716, 84598
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P23458, P52332
Gene Symbols:
JAK1
Immunogen:
Residues 980-1030 of human JAK1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HSD11B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hsd11b1
Gene Alias: 11 beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD type 1, 11-beta-HSD1, 11beta-HSD1, 11beta-HSD-1, 11beta-HSD1A, 11-beta-hydroxysteroid dehydrogenase, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A), cortocosteroid 11-beta dehydrogenase, CORTRD2, HDL, HSD11, HSD11B, Hsd11b1, HSD11L, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid dehydrogenase, 11 beta type 1, LRRGT00065, MGC13539, OTTHUMP00000034650, SDR26C1, short chain dehydrogenase/reductase family 26C member 1, short chain dehydrogenase/reductase family 26C, member 1, short-chain reductase, short-chain reductase/dehydrogenase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15483, 25116, 3290
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P16232, P28845, P50172
Gene Symbols: Hsd11b1
Immunogen: Synthetic peptide, corresponding to amino acids 43-88 of Human HSD11B1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HSD11B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hsd11b1
Gene Alias:
11 beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD type 1, 11-beta-HSD1, 11beta-HSD1, 11beta-HSD-1, 11beta-HSD1A, 11-beta-hydroxysteroid dehydrogenase, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A), cortocosteroid 11-beta dehydrogenase, CORTRD2, HDL, HSD11, HSD11B, Hsd11b1, HSD11L, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid dehydrogenase, 11 beta type 1, LRRGT00065, MGC13539, OTTHUMP00000034650, SDR26C1, short chain dehydrogenase/reductase family 26C member 1, short chain dehydrogenase/reductase family 26C, member 1, short-chain reductase, short-chain reductase/dehydrogenase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15483, 25116, 3290
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P16232, P28845, P50172
Gene Symbols:
Hsd11b1
Immunogen:
Synthetic peptide, corresponding to amino acids 43-88 of Human HSD11B1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG