PIPA586549

IRF3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586549-Each-of-1 In Stock ₹ 44,705.10

PIPA586549 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IRF3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRF3

Gene Alias

C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

292892, 3661, 54131

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

P70671, Q14653

Gene Symbols

IRF3

Immunogen

Synthetic peptide, corresponding to amino acids 358-412 of Human IRF-3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
  • It plays a critical role in the innate immune response against DNA and RNA viruses
  • IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
  • It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
  • IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
  • It is phosphorylated by IKBKE and TBK1 kinases
  • This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
  • Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Compare Similar Items

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Img

Thermo Scientific

PIPA586549

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Antigen:
IRF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292892, 3661, 54131

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P70671, Q14653

Gene Symbols:
IRF3

Immunogen:
Synthetic peptide, corresponding to amino acids 358-412 of Human IRF-3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586550

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Antigen:
PKC theta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKCQ

Gene Alias:
A130035A12Rik, AW494342, EC 2.7.11.13, kinase nPKC-theta, KPCT, MGC126514, MGC141919, nPKC-theta, PKC theta, PKC-0, Pkcq, PKCtheta, PKC-theta, PRKCQ, PRKCT, protein kinase C theta, protein kinase C theta type, protein kinase C, theta, RP11-563J2.1, si:ch211-239o15.1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18761, 5588, 85420

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q02111, Q04759, Q9WTQ0

Gene Symbols:
PRKCQ

Immunogen:
Synthetic peptide, corresponding to amino acids 520-570 of Human PKC theta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586551

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Antigen:
TGFBR1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TGFBR1

Gene Alias:
AAT5, activin A receptor type II-like kinase, 53kDa, activin A receptor type II-like protein kinase of 53kD, Activin receptor-like kinase 5, ACVRLK4, ALK5, Alk-5, AU017191, ESK2, ESS1, LDS1, LDS1A, LDS2A, MSSE, mutant transforming growth factor beta receptor I, ser, serine/threonine-protein kinase receptor R4, SKR4, TbetaRI, tbetaR-I, tgf beta receptor 1, TGF-beta receptor type I, TGF-beta receptor type-1, TGF-beta type I receptor, TGFBR1, TGFR1, TGFR-1, Transfor, transforming growth factor beta receptor 1, transforming growth factor beta receptor I, transforming growth factor, beta receptor 1, transforming growth factor, beta receptor I, transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa), transforming growth factor-beta receptor type I

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
21812, 29591, 7046

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P36897, P80204, Q64729

Gene Symbols:
TGFBR1

Immunogen:
Synthetic peptide, corresponding to amino acids 150-200 of Human TGFbeta RI.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586552

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Antigen:
NR4A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NR4A1

Gene Alias:
early response protein NAK1, Gfrp, GFRP1, growth factor-inducible nuclear protein N10, Hbr1, Hbr-1, Hmr, hormone receptor, immediate early gene transcription factor NGFI-B, MGC9485, N10, NAK1, NAK-1, nerve growth factor IB nuclear receptor variant 1, nerve growth factor induced protein I-B, nerve growth factor-induced protein I-B, Ngfib, NGFI-B, NP10, Nr4a1, Nuclear hormone receptor NUR/77, nuclear protein N10, Nuclear receptor subfamily 4 group A member 1, nuclear receptor subfamily 4, group A, member 1, NUR77, Orphan nuclear receptor HMR, orphan nuclear receptor TR3, Orphan receptor tr3, ST-59, steroid receptor TR3, testicular receptor 3, TIS1, TR3, TR3 orphan receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15370, 3164, 79240

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P12813, P22736, P22829

Gene Symbols:
NR4A1

Immunogen:
Synthetic peptide, corresponding to amino acids 320-365 of Human Nur77/NR4A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG