PIPA587506
IRF3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587506-Each-of-1 | In Stock | ₹ 44,619.54 |
PIPA587506 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
IRF3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292892, 3661, 54131
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration
0.93 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P70671, Q14653
Gene Symbols
IRF3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 310-410 of human IRF3 (NP_0015621)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: 293T, HeLa, Jurkat, HepG2, Mouse liver; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: EVPKDKEGGV FDLGPFIVDL ITFTEGSGRS PRYALWFCVG ESWPQDQPWT KRLVMVKVVP TCLRALVEMA RVGGASSLEN TVDLHISNSH PLSLTSDQYK A IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
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Antigen: IRF3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 292892, 3661, 54131
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration: 0.93 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P70671, Q14653
Gene Symbols: IRF3
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 310-410 of human IRF3 (NP_0015621)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IRF3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
292892, 3661, 54131
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Concentration:
0.93 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P70671, Q14653
Gene Symbols:
IRF3
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 310-410 of human IRF3 (NP_0015621)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PTCH
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ptch1
Gene Alias: A230106A15Rik, BCNS, etID309849.2, FLJ26746, FLJ42602, HGNC:9585, HPE7, lep, leprechaun, mes, mesenchymal dysplasia, NBCCS, OTTHUMP00000021709, OTTHUMP00000021710, patched, Patched 1, patched 2, patched homolog 1, patched homolog 2, patched protein, patched1, patched-2 protein, patched-like protein, protein patched homolog 1, Ptc, ptc1, ptc-1, ptc2, Ptch, PTCH protein +12b, PTCH protein +4', PTCH protein -10, PTCH protein -3, PTCH protein -3,4,5, PTCH1, Ptch1 protein +12b, PTCH11, Ptch2, RP11-435O5.3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19206, 5727, 89830
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.82 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q13635, Q61115
Gene Symbols: Ptch1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1214-1312 of human PTCH1 (NP_0002552)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTCH
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ptch1
Gene Alias:
A230106A15Rik, BCNS, etID309849.2, FLJ26746, FLJ42602, HGNC:9585, HPE7, lep, leprechaun, mes, mesenchymal dysplasia, NBCCS, OTTHUMP00000021709, OTTHUMP00000021710, patched, Patched 1, patched 2, patched homolog 1, patched homolog 2, patched protein, patched1, patched-2 protein, patched-like protein, protein patched homolog 1, Ptc, ptc1, ptc-1, ptc2, Ptch, PTCH protein +12b, PTCH protein +4', PTCH protein -10, PTCH protein -3, PTCH protein -3,4,5, PTCH1, Ptch1 protein +12b, PTCH11, Ptch2, RP11-435O5.3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19206, 5727, 89830
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.82 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q13635, Q61115
Gene Symbols:
Ptch1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1214-1312 of human PTCH1 (NP_0002552)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: cIAP2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BIRC3
Gene Alias: AIP 2, AIP1, Api1, Api2, apoptosis inhibitor 1, apoptosis inhibitor 2, AW107670, baculoviral IAP repeat containing 3, baculoviral IAP repeat-containing 2, baculoviral IAP repeat-containing 3, baculoviral IAP repeat-containing protein 3, Birc2, Birc3, Cellular inhibitor of apoptosis 2, cIAP1, cIAP-1, cIAP2, C-IAP2, cIAP-2, H HIAP1, H MALT2, HAIP1, HIAP1, hIAP-1, HIAP2, IAP homolog, IAP homolog C, IAP1, IAP-1, IAP2, Inhibitor of apoptosis protein 1, MALT2, mammalian IAP homolog C, MIAP1, mIAP-1, MIAP2, MIHB, MIHC, RING finger protein 49, RING-type E3 ubiquitin transferase BIRC3, RNF49, TNFR2-TRAF signaling complex protein, TNFR2-TRAF-signaling complex protein 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11796, 330, 78971
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.81 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O08863, Q13489
Gene Symbols: BIRC3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-130 of human cIAP2 (NP_0011561)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
cIAP2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BIRC3
Gene Alias:
AIP 2, AIP1, Api1, Api2, apoptosis inhibitor 1, apoptosis inhibitor 2, AW107670, baculoviral IAP repeat containing 3, baculoviral IAP repeat-containing 2, baculoviral IAP repeat-containing 3, baculoviral IAP repeat-containing protein 3, Birc2, Birc3, Cellular inhibitor of apoptosis 2, cIAP1, cIAP-1, cIAP2, C-IAP2, cIAP-2, H HIAP1, H MALT2, HAIP1, HIAP1, hIAP-1, HIAP2, IAP homolog, IAP homolog C, IAP1, IAP-1, IAP2, Inhibitor of apoptosis protein 1, MALT2, mammalian IAP homolog C, MIAP1, mIAP-1, MIAP2, MIHB, MIHC, RING finger protein 49, RING-type E3 ubiquitin transferase BIRC3, RNF49, TNFR2-TRAF signaling complex protein, TNFR2-TRAF-signaling complex protein 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11796, 330, 78971
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.81 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O08863, Q13489
Gene Symbols:
BIRC3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-130 of human cIAP2 (NP_0011561)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CHOP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DDIT3
Gene Alias: C/EBP homologous protein, C/EBP homoologous protein 10, C/EBP zeta, C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, CEBPZ, CHOP, CHOP10, CHOP-10, Ddit3, DDIT-3, ddit3.L, DNA damage inducible transcript 3, DNA damage inducible transcript 3 L homeolog, DNA damage-inducible transcript 3 protein, DNA-damage inducible transcript 3, DNA-damage-inducible transcript 3, GADD153, growth arrest and DNA damage-inducible, growth arrest and DNA damage-inducible protein GADD153, Growth arrest and DNA-damage-inducible protein GADD153, MGC4154, transcription factor GADD153, Xchop, XELAEV_18013440mg
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13198
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.89 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P35639
Gene Symbols: DDIT3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human DDIT3/CHOP (NP_0040742)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
CHOP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DDIT3
Gene Alias:
C/EBP homologous protein, C/EBP homoologous protein 10, C/EBP zeta, C/EBP-homologous protein, C/EBP-homologous protein 10, CCAAT/enhancer-binding protein homologous protein, CEBPZ, CHOP, CHOP10, CHOP-10, Ddit3, DDIT-3, ddit3.L, DNA damage inducible transcript 3, DNA damage inducible transcript 3 L homeolog, DNA damage-inducible transcript 3 protein, DNA-damage inducible transcript 3, DNA-damage-inducible transcript 3, GADD153, growth arrest and DNA damage-inducible, growth arrest and DNA damage-inducible protein GADD153, Growth arrest and DNA-damage-inducible protein GADD153, MGC4154, transcription factor GADD153, Xchop, XELAEV_18013440mg
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13198
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.89 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P35639
Gene Symbols:
DDIT3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human DDIT3/CHOP (NP_0040742)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG