PIPA586605
IkB alpha Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586605-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586605 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
IkB alpha
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NFKBIA
Gene Alias
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18035, 4792
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P25963, Q9Z1E3
Gene Symbols
NFKBIA
Immunogen
Synthetic peptide, corresponding to the N-terminal of Human IkB-alpha.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- IkB-alpha is a 40 kDa protein that functions to inhibit NF- kappaB activity
- The inhibition occurs via protein-protein interaction between I kappaB proteins and NF- kappaB dimers in the cytosol
- The interaction of I kappa B-alpha with NF- kappaB masks the nuclear localization sequence of NF- kappaB, preventing NF- kappaB translocation to the nucleus
- A variety of stimuli can activate gene expression by liberating NF- kappaB through the degradation of I kappaB alpha
- These stimuli include the proinflammatory cytokines TNF- alpha and IL-1 beta, chemokines, PMA, growth factors, LPS, UV irradiation, viral infection, as well as various chemical and physical stresses
- In humans, the gene is located on the q arm of chromosome 14
- Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB
- IkB kinase alpha (IKK alpha), previously designated CHUK, interacts with IkB-alpha and specifically phosphorylates IkB-alpha on the sites that trigger its degradation Serines 32 and 36
- IKK alpha appears to be critical for NFkB activation in response to proinflammatory cytokines
- Phosphorylation of IkB by IKK alpha is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1
- The functional IKK complex contains three subunits, IKK alpha, IKK beta and IKK gamma, and each appear to make essential contributions to IkB phosphorylation.
Compare Similar Items
Show Difference
Antigen: IkB alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFKBIA
Gene Alias: AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18035, 4792
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P25963, Q9Z1E3
Gene Symbols: NFKBIA
Immunogen: Synthetic peptide, corresponding to the N-terminal of Human IkB-alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IkB alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFKBIA
Gene Alias:
AI462015, ECI-6, ECI-6/IKBA, I kappa B-alpha, I(Kappa)B(alpha), I79_018146, IkappaB alpha, IkappaBalpha, I-kappaBalpha, I-kappa-B-alpha, Ikba, IKBalpha, IKB-alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells alpha, Inhibitor of nuclear factor of kappa light chain gene enhancer in B-cells, alpha, MAD3, MAD-3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappaB inhibitor alpha, NF-kappa-B inhibitor alpha, NFKB inhibitor alpha, NFKBI, Nfkbia, nuclear factor of kappa light chain gene enhancer in B-cells, nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, alpha, nuclear factor of kappa light polyp gene enhancer in B-cell 1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, Rel-associated pp40, REL-associated protein pp40, RL/IF-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18035, 4792
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P25963, Q9Z1E3
Gene Symbols:
NFKBIA
Immunogen:
Synthetic peptide, corresponding to the N-terminal of Human IkB-alpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: 4EBP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF4EBP1
Gene Alias: 4EBP1, 4E-BP1, AA959816, BP-1, eIF4E-binding protein 1, EIF4EBP1, eukaryotic translation initiation factor 4E binding protein 1, eukaryotic translation initiation factor 4E-binding protein 1, MGC431, MGC4316, P/OKCL.6, PHAS-1, PHAS-I, Phosphorylated heat- and acid-stable protein regulated by insulin 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116636, 13685, 1978
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q13541, Q60876, Q62622
Gene Symbols: EIF4EBP1
Immunogen: Synthetic peptide, corresponding to amino acids 17-60 of Human 4E-BP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
4EBP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF4EBP1
Gene Alias:
4EBP1, 4E-BP1, AA959816, BP-1, eIF4E-binding protein 1, EIF4EBP1, eukaryotic translation initiation factor 4E binding protein 1, eukaryotic translation initiation factor 4E-binding protein 1, MGC431, MGC4316, P/OKCL.6, PHAS-1, PHAS-I, Phosphorylated heat- and acid-stable protein regulated by insulin 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116636, 13685, 1978
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q13541, Q60876, Q62622
Gene Symbols:
EIF4EBP1
Immunogen:
Synthetic peptide, corresponding to amino acids 17-60 of Human 4E-BP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Stathmin 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stmn1
Gene Alias: 19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16765, 29332, 3925
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P13668, P16949, P54227
Gene Symbols: Stmn1
Immunogen: Synthetic peptide, corresponding to the N-terminus of Human Op18.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Stathmin 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stmn1
Gene Alias:
19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16765, 29332, 3925
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P13668, P16949, P54227
Gene Symbols:
Stmn1
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human Op18.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Stathmin 1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stmn1
Gene Alias: 19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16765, 29332, 3925
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P13668, P16949, P54227
Gene Symbols: Stmn1
Immunogen: Synthetic peptide, corresponding to the N-terminus of Human Op18.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Stathmin 1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stmn1
Gene Alias:
19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16765, 29332, 3925
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P13668, P16949, P54227
Gene Symbols:
Stmn1
Immunogen:
Synthetic peptide, corresponding to the N-terminus of Human Op18.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG