PIPA586228

IKK beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA586228-Each-of-1 In Stock ₹ 44,705.10

PIPA586228 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IKK beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16150, 3551, 84351

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O14920, O88351, Q9QY78

Gene Symbols

Ikbkb

Immunogen

Synthetic peptide, corresponding to amino acids 161-210 of Human IKKbeta.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
  • Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
  • IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
  • These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
  • In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

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Thermo Scientific

PIPA586228

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Antigen:
IKK beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16150, 3551, 84351

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O14920, O88351, Q9QY78

Gene Symbols:
Ikbkb

Immunogen:
Synthetic peptide, corresponding to amino acids 161-210 of Human IKKbeta.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586229

--


Antigen:
Ku80

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XRCC5

Gene Alias:
86 kDa subunit of Ku antigen, AI314015, ATP-dependent DNA helicase 2 subunit 2, ATP-dependent DNA helicase II 80 kDa subunit, CTC box-binding factor 85 kDa subunit, CTC85, CTCBF, DNA repair protein XRCC5, FLJ39089, G22p2, HGNC:12833, KARP1, KARP-1, Ku autoantigen, ku autoantigen protein p86 homolog, Ku autoantigen, 80kD), Ku autoantigen, 80kDa, Ku p80, Ku80, Ku-80, Ku86, Ku-86, Ku86 autoantigen related protein 1, KUB2, Kup80, Lupu, lupus, lupus Ku autoantigen protein p86, NFIV, nuclear factor IV, OTTHUMP00000164061, OTTHUMP00000206791, Thyroid-lupus autoantigen, TLAA, X-ray repair complementing defective repair in Chinese hamster cells 5, X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining), X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining, Ku autoantigen, 80kDa), X-ray repair cross complementation (double-strand-break rejoining, X-ray repair cross complementation (double-strand-break

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22596, 363247, 7520

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P13010, P27641

Gene Symbols:
XRCC5

Immunogen:
Synthetic peptide, corresponding to amino acids 680-720 of Human XRCC5.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586230

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Antigen:
Lyn

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LYN

Gene Alias:
AA407514, CD180, CD180 antigen, CD180 molecule, CH73-38P6.3, FLJ26625, Hck-2, JTK8, lck/Yes-related novel protein tyrosine kinase, LY64, Ly78, lymphocyte antigen 64, lymphocyte antigen-64, radioprotective, 105kDa, LYN, lyn protein non-receptor kinase, lyn protein tyrosine kinase, LYN proto-oncogene, Src family tyrosine kinase, p53Lyn, p56Lyn, Radioprotective 105 kDa protein, RP105, Tyrosine-protein kinase Lyn, v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, v-yes-1 Yamaguchi sarcoma viral related oncogene protein-like protein, Yamaguchi sarcoma viral (v-yes-1) oncogene homolog, zgc:92124

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17096, 4067, 81515

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P07948, P25911, Q07014

Gene Symbols:
LYN

Immunogen:
Synthetic peptide, corresponding to amino acids 461-510 of Human Lyn.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586231

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Antigen:
BAD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BAD

Gene Alias:
AI325008, BAD, Bbc2, Bbc6, Bcl2 antagonist of cell death, BCL2 associated agonist of cell death, bcl-2 associated death agonist, Bcl2-antagonist of cell death, BCL2-antagonist of cell death protein, bcl2-associated agonist of cell death, bcl2-associated death promoter, bcl-2-binding component 6, BCL2-binding component 6, BCL2-binding protein, BCL2L8, bcl2-L-8, Bcl-2-like protein 8, BCL-X/BCL-2 binding protein, bcl-XL/Bcl-2-associated death promoter, hypothetical protein LOC615013, OTTMUSP00000017561, OTTMUSP00000022400

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12015, 572, 64639

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O35147, Q61337, Q92934

Gene Symbols:
BAD

Immunogen:
Synthetic peptide, corresponding to amino acids 72-126 of Human Bad.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG