PIPA586059

IKK beta Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586059-Each-of-1 In Stock ₹ 44,705.10

PIPA586059 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IKK beta

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ikbkb

Gene Alias

AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

16150, 3551, 84351

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

O14920, O88351, Q9QY78

Gene Symbols

Ikbkb

Immunogen

Recombinant protein within Human IKK beta aa 501-649

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Rabbit Polyclonal Antibody Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
  • Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
  • IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
  • These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
  • In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
  • Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).

Compare Similar Items

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Thermo Scientific

PIPA586059

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Antigen:
IKK beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
16150, 3551, 84351

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
O14920, O88351, Q9QY78

Gene Symbols:
Ikbkb

Immunogen:
Recombinant protein within Human IKK beta aa 501-649

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586060

--


Antigen:
UBA3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Uba3

Gene Alias:
A830034N06Rik; AI256736; AI848246; AW546539; DKFZp566J164; hUBA3; MGC22384; NAE2; NEDD8-activating enzyme E1 catalytic subuni-like protein; NEDD8-activating enzyme E1 catalytic subunit; NEDD8-activating enzyme E1 subunit 2; NEDD8-activating enzyme E1C; Nedd8-activating enzyme hUba3; Uba3; UBA3, ubiquitin-activating enzyme E1 homolog; UBE1C; ubiquitin like modifier activating enzyme 3; ubiquitin-activating enzyme 3; Ubiquitin-activating enzyme E1C; ubiquitin-activating enzyme E1C (homologous to yeast UBA3); ubiquitin-activating enzyme E1C (UBA3 homolog, yeast); ubiquitin-like modifier activating enzyme 3; ubiquitin-like modifier-activating enzyme 3; Unknown (protein for MGC:140052); wu:fb75e04; wu:fc37b11; zgc:55528

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
117553, 22200, 9039

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q8C878, Q8TBC4, Q99MI7

Gene Symbols:
Uba3

Immunogen:
Recombinant protein within Human UBE1C aa 220-424

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586061

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Antigen:
FBXL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FBXL2

Gene Alias:
2810423A21Rik, DKFZP564P0622, FBL2, Fbl3, F-box and leucine rich repeat protein 2, F-box and leucine-rich repeat protein 2, F-box protein containing leucine-rich repeats, F-box protein FBL2/FBL3, F-box/LRR-repeat protein 2, FBXL2, RGD1562243

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
25827, 363156, 72179

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q8BH16, Q9UKC9

Gene Symbols:
FBXL2

Immunogen:
Synthetic peptide corresponding to Human FBXL2 aa 51-100

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586062

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Antigen:
Bax

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BAX

Gene Alias:
apoptosis regulator BAX; Apoptosis regulator Bcl-X; Bax; Bax zeta; BAX-ALPHA; Bax-alpha protein; Baxdelta2G9; Baxdelta2G9omega; Baxdelta2omega; BCL2 associated X protein; BCL2 associated X, apoptosis regulator; BCL2 like 1; BCL2-associated protein; Bcl-2-associated protein Bax; Bcl2-associated protein Bax; Bcl-2-associated X protein; BCL2-associated X protein; BCL2-associated X protein omega; BCL2L; BCL2L1; Bcl2-L-1; BCL2L4; Bcl2-L-4; BCL2-like 1; bcl-2-like protein 1; Bcl-2-like protein 4; BCLX; Bcl-X; BCL-XL/S; PPP1R52; protein phosphatase 1, regulatory subunit 52

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12028, 581

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 50% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q07812, Q07813

Gene Symbols:
BAX

Immunogen:
Synthetic peptide within Human BAX aa 1-50

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG