PIPA587491
IKK beta Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587491-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587491 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
IKK beta
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ikbkb
Gene Alias
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3551
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.76 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O14920
Gene Symbols
Ikbkb
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 400-669 of IKK beta (NP_0015471)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QISPRPQPES VSCILQEPKR NLAFFQLRKV WGQVWHSIQT LKEDCNRLQQ GQRAAMMNLL RNNSCLSKMK NSMASMSQQL KAKLDFFKTS IQIDLEKYSE QTEFGITSDK LLLAWREMEQ AVELCGRENE VKLLVERMMA LQTDIVDLQR SPMGRKQGGT LDDLEEQARE LYRRLREKPR DQRTEGDSQE MVRLLLQAIQ SFEKKVRVIY TQLSKTVVCK QKALELLPKV EEVVSLMNED EKTVVRLQEK RQKELWNLLK IACSKVRGPV Positive Samples: Jurkat, HepG2; Cellular Location: Cytoplasm, Membrane raft, Nucleus Phosphorylation of serine residues on the I-kappa-B proteins by IKK kinases, including IKBKB, marks them for destruction via the ubiquitination pathway, allowing activation of the NF-kappa-B complex
- Inhibitor of nuclear factor kappa-B kinase subunit beta (IKK beta) is a serine kinase that plays an essential role in the NF-kaapa-B signaling pathway which is activated by mulitple stimuli such as inflammatory cytokines, bacterial, or viral products, DNA damages, or other cellular stresses
- IKK beta acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation and phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues
- These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome
- In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis
- Mutations affecting the IKK beta gene can result in Immunodeficiency 15 (IMD15).
Compare Similar Items
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Antigen: IKK beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ikbkb
Gene Alias: AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3551
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.76 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O14920
Gene Symbols: Ikbkb
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 400-669 of IKK beta (NP_0015471)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IKK beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ikbkb
Gene Alias:
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3551
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.76 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O14920
Gene Symbols:
Ikbkb
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 400-669 of IKK beta (NP_0015471)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HMGB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hmgb1
Gene Alias: Ac2-008, amphoterin, Amphoterin antibody, DEF, DKFZp686A04236, Heparin-binding protein p30, high mobility group 1, high mobility group 1 protein, high mobility group box 1, high mobility group protein 1, High mobility group protein B1, high mobility group protein HMG1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, high-mobility-group protein, Hmg1, HMG-1, HMG3, HMG3 antibody, hmgb 1, HMGB1, hmgb-1, HMGB1 protein, hypothetical protein, non-histone protein HMG1, p30, RCJMB04_15a21, RP11-550P23.1, SBP-1, Sulfoglucuronyl carbohydrate binding protein, unnamed protein product
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15289, 25459, 3146
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.22 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P09429, P63158, P63159
Gene Symbols: Hmgb1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 69-168 of human HMGB1 (NP_0021191)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HMGB1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hmgb1
Gene Alias:
Ac2-008, amphoterin, Amphoterin antibody, DEF, DKFZp686A04236, Heparin-binding protein p30, high mobility group 1, high mobility group 1 protein, high mobility group box 1, high mobility group protein 1, High mobility group protein B1, high mobility group protein HMG1, high-mobility group (nonhistone chromosomal) protein 1, high-mobility group box 1, high-mobility-group protein, Hmg1, HMG-1, HMG3, HMG3 antibody, hmgb 1, HMGB1, hmgb-1, HMGB1 protein, hypothetical protein, non-histone protein HMG1, p30, RCJMB04_15a21, RP11-550P23.1, SBP-1, Sulfoglucuronyl carbohydrate binding protein, unnamed protein product
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15289, 25459, 3146
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.22 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P09429, P63158, P63159
Gene Symbols:
Hmgb1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 69-168 of human HMGB1 (NP_0021191)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: VE-cadherin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDH5
Gene Alias: 7B4, 7B4 antigen, 7B4/cadherin-5, AA408225, cadherin 5, cadherin 5, type 2 (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular epithelium), cadherin-5, cadherin-5, cd144 antigen, VE cadherin, Cd144, cd144 antigen, CDH5, cell-cell adhesion protein, endothelial-specific cadherin, vascular endothelial cadherin, vascular endothelial cadherin precursor, Vec, VEcad, VE-Cad, VE-cadherin, VECD
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1003, 12562
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.01 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P33151, P55284
Gene Symbols: CDH5
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 259-358 of human VE Cadherin (NP_0017862)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
VE-cadherin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDH5
Gene Alias:
7B4, 7B4 antigen, 7B4/cadherin-5, AA408225, cadherin 5, cadherin 5, type 2 (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular epithelium), cadherin-5, cadherin-5, cd144 antigen, VE cadherin, Cd144, cd144 antigen, CDH5, cell-cell adhesion protein, endothelial-specific cadherin, vascular endothelial cadherin, vascular endothelial cadherin precursor, Vec, VEcad, VE-Cad, VE-cadherin, VECD
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1003, 12562
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.01 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P33151, P55284
Gene Symbols:
CDH5
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 259-358 of human VE Cadherin (NP_0017862)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: CSK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CSK
Gene Alias: AW212630, CSK, CSK, non-receptor tyrosine kinase, C-SRC kinase, c-src tyrosine kinase, C-terminal Src kinase, MGC117393, p50CSK, protein-tyrosine kinase (CSK), protein-tyrosine kinase CYL, Protein-tyrosine kinase MPK-2, Tyrosine-protein kinase CSK
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12988, 1445, 315707
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.14 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P32577, P41240, P41241
Gene Symbols: CSK
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CSK (NP_0011206621)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CSK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CSK
Gene Alias:
AW212630, CSK, CSK, non-receptor tyrosine kinase, C-SRC kinase, c-src tyrosine kinase, C-terminal Src kinase, MGC117393, p50CSK, protein-tyrosine kinase (CSK), protein-tyrosine kinase CYL, Protein-tyrosine kinase MPK-2, Tyrosine-protein kinase CSK
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12988, 1445, 315707
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.14 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P32577, P41240, P41241
Gene Symbols:
CSK
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CSK (NP_0011206621)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG