PIPA586950

Apolipoprotein B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586950-Each-of-1 In Stock ₹ 52,020.48

PIPA586950 - Each of 1

₹ 52,020.48

In Stock

Quantity

1

Base Price: ₹ 52,020.48

GST (18%): ₹ 9,363.686

Total Price: ₹ 61,384.166

Antigen

Apolipoprotein B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

APOB

Gene Alias

Aa1064, Ac1-060, AI315052, Apo B100, Apo B-100, Apo B-48, APOB, apo-B, ApoB 100, ApoB 48, ApoB-100, apob-48, apolipo b, apolipoprotein B, apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, apolipoprotein B PI, Apolipoprotein B100, apolipoprotein B-100, apolipoprotein B46, apolipoprotein B47, apolipoprotein B48, Apolipoprotein B-48, apolipoprotein B49, FLDB, LDLCQ4, LOX-1, mCG_129875, MGC176318, Ox-LDL receptor 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

238055, 338, 54225

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

E9Q414, P04114, Q7TMA5

Gene Symbols

APOB

Immunogen

Recombinant protein of human APOB.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Apolipoprotein B (apo B) in human plasma is a major protein of low density lipoproteins (LDL) with a molecular mass of approximately 260-500 kDa
  • Apolipoprotein B binds to specific receptors on cell membranes and is involved in removal of LDL and very low density lipoprotein (VLDL) cholesterol from circulation
  • Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood
  • LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearance of cholesterol from the circulation
  • In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36
  • Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described
  • MDA-oxidized LDL appear to be different from LDL oxidized by other means
  • Apolipoprotein B is mostly synthesized in the liver, and is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a)
  • Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis
  • Normal plasma apolipoprotein B levels are around 800mg/L
  • Apolipoprotein B occurs in plasma as two main isoforms, apoB-48 and apoB-100
  • The intestinal and the hepatic forms of Apolipoprotein B are encoded by a single gene from a single, very long mRNA
  • The two isoforms share a common N-terminal sequence
  • The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination
  • Mutations in the Apolipoprotein B gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective Apolipoprotein B, diseases affecting plasma cholesterol and Apolipoprotein B levels.

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Show Difference

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Thermo Scientific

PIPA586950

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Antigen:
Apolipoprotein B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APOB

Gene Alias:
Aa1064, Ac1-060, AI315052, Apo B100, Apo B-100, Apo B-48, APOB, apo-B, ApoB 100, ApoB 48, ApoB-100, apob-48, apolipo b, apolipoprotein B, apolipoprotein B (including Ag(x) antigen), Apolipoprotein B 100, Apolipoprotein B 48, apolipoprotein B PI, Apolipoprotein B100, apolipoprotein B-100, apolipoprotein B46, apolipoprotein B47, apolipoprotein B48, Apolipoprotein B-48, apolipoprotein B49, FLDB, LDLCQ4, LOX-1, mCG_129875, MGC176318, Ox-LDL receptor 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238055, 338, 54225

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
E9Q414, P04114, Q7TMA5

Gene Symbols:
APOB

Immunogen:
Recombinant protein of human APOB.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586952

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Antigen:
XBP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Xbp1

Gene Alias:
D11Ertd39e, Hepatocarcinogenesis-related transcription factor, HTF, OTTHUMP00000028682, Tax-responsive element-binding protein 5, tax-responsive element-binding protein 5 homolog, TREB5, TREB-5, X-box binding protein 1, X-box-binding protein 1, X-box-binding protein 1, cytoplasmic form, X-box-binding protein 1, luminal form, XBP1, XBP-1, XBP2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22433, 289754, 7494

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O35426, P17861, Q9R1S4

Gene Symbols:
Xbp1

Immunogen:
Recombinant protein of human XBP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586953

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Antigen:
IGFBP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP2

Gene Alias:
AI255832, BP2, BRL-BP, IBP2, IBP-2, IGF binding protein 2, IGF-binding protein 2, IGFBP, IGFBP2, IGFBP-2, IGF-BP53, ILGFBPA, Insulin like growth factor binding protein, insulin like growth factor binding protein 2, insulin-like growth factor binding protein 2, insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor-binding protein 2, mIGFBP-2, OTTHUMP00000207753

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16008, 25662, 3485

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P12843, P18065, P47877

Gene Symbols:
IGFBP2

Immunogen:
A synthetic peptide of human IGFBP2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586954

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Antigen:
CD53

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cd53

Gene Alias:
AI323659, antigen MOX44 identified by monoclonal antibody MRC-OX44, Cd53, CD53 antigen, CD53 glycoprotein, CD53 molecule, CD53 tetraspan antigen, cell surface antigen, cell surface glycoprotein CD53, Leukocyte antigen MRC OX-44, leukocyte surface antigen CD53, MOX44, OX44, Ox-44, tetraspanin-25, transmembrane glycoprotein, TSPAN25, tspan-25

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12508, 963

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P19397, Q61451

Gene Symbols:
Cd53

Immunogen:
Recombinant protein of human CD53.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG