PIPA587244
UFD1L Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587244-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA587244 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
UFD1L
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UFD1
Gene Alias
RGD:619822}, UB fusion protein 1, UB fusion protein 1 {ECO:0000250, ubiquitin fusion degradation 1 like, ubiquitin fusion degradation 1 like (yeast), Ubiquitin fusion degradation protein 1, Ubiquitin fusion degradation protein 1 homolog, ubiquitin fusion degradation protein 1 homolog {ECO:0000250, Ubiquitin recognition factor in ER-associated degradation protein 1, UFD1, UFD1L, ufd1l {ECO:0000312, UniProtKB:Q92890}
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22230, 7353
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P70362, Q92890
Gene Symbols
UFD1
Immunogen
Recombinant full length Human UFD1L.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Ubiquitin-mediated proteolysis requires the transfer of ubiquitin (Ub) to lysine groups on selected cellular proteins, which then potentiates the proteolytic degradation of these protein conjugates by the 26S proteasome
- Ub-fusions are cleaved by Ub-specific processing proteases (UBps) or alternatively by the Ub-fusion degradation (UFD) pathway
- The UBP pathway targets the C-terminal glycine residue on Ub that is involved in the formation of Ub-conjugates, while UFD proteins preferentially cleave Ub-conjugated proteins that contain an amino acid substitution at this glycine residue
- The UFD1 protein was originally characterized in the yeast S
- cerevisiae and subsequently, the human homolog UFD1 or UFD1L was identified
- In vitro, UFD1 attenuates the degradation of Ub-fusions, which have a proline or valine residue substituted at the Gly76 moiety, by the selective multiubiquitination of the Ub chain of the Ub-conjugate
- Mutations within the UFD1 gene are implicated in the development of CATCH22 syndrome, which is characterized by cardiac defects, cleft palate and hypocalcemia, suggesting that this proteolytic pathway may be involved in the progression of these developmental defects.
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Antigen: UFD1L
Classification: Polyclonal
Conjugate: Unconjugated
Gene: UFD1
Gene Alias: RGD:619822}, UB fusion protein 1, UB fusion protein 1 {ECO:0000250, ubiquitin fusion degradation 1 like, ubiquitin fusion degradation 1 like (yeast), Ubiquitin fusion degradation protein 1, Ubiquitin fusion degradation protein 1 homolog, ubiquitin fusion degradation protein 1 homolog {ECO:0000250, Ubiquitin recognition factor in ER-associated degradation protein 1, UFD1, UFD1L, ufd1l {ECO:0000312, UniProtKB:Q92890}
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22230, 7353
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P70362, Q92890
Gene Symbols: UFD1
Immunogen: Recombinant full length Human UFD1L.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
UFD1L
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
UFD1
Gene Alias:
RGD:619822}, UB fusion protein 1, UB fusion protein 1 {ECO:0000250, ubiquitin fusion degradation 1 like, ubiquitin fusion degradation 1 like (yeast), Ubiquitin fusion degradation protein 1, Ubiquitin fusion degradation protein 1 homolog, ubiquitin fusion degradation protein 1 homolog {ECO:0000250, Ubiquitin recognition factor in ER-associated degradation protein 1, UFD1, UFD1L, ufd1l {ECO:0000312, UniProtKB:Q92890}
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22230, 7353
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P70362, Q92890
Gene Symbols:
UFD1
Immunogen:
Recombinant full length Human UFD1L.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: WFDC2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WFDC2
Gene Alias: 1600023A02Rik, dJ461P17.6, EDDM4, epididymal protein 4, epididymal secretory protein 4, Epididymal secretory protein E4, epididymis-specific, whey-acidic protein type, four-disulfide core, HE4, Major epididymis-specific protein E4, MGC57529, putative protease inhibitor WAP5, RE4, WAP domain containing protein HE4-V4, WAP domain-containing protein HE4, WAP four-disulfide core domain 2, WAP four-disulfide core domain protein 2, WAP5, Wfdc2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10406, 286888, 67701
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: Q14508, Q8CHN3, Q9DAU7
Gene Symbols: WFDC2
Immunogen: Recombinant full length Human WDR68.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
WFDC2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WFDC2
Gene Alias:
1600023A02Rik, dJ461P17.6, EDDM4, epididymal protein 4, epididymal secretory protein 4, Epididymal secretory protein E4, epididymis-specific, whey-acidic protein type, four-disulfide core, HE4, Major epididymis-specific protein E4, MGC57529, putative protease inhibitor WAP5, RE4, WAP domain containing protein HE4-V4, WAP domain-containing protein HE4, WAP four-disulfide core domain 2, WAP four-disulfide core domain protein 2, WAP5, Wfdc2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10406, 286888, 67701
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
Q14508, Q8CHN3, Q9DAU7
Gene Symbols:
WFDC2
Immunogen:
Recombinant full length Human WDR68.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: HSD11B1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Hsd11b1
Gene Alias: 11 beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD type 1, 11-beta-HSD1, 11beta-HSD1, 11beta-HSD-1, 11beta-HSD1A, 11-beta-hydroxysteroid dehydrogenase, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A), cortocosteroid 11-beta dehydrogenase, CORTRD2, HDL, HSD11, HSD11B, Hsd11b1, HSD11L, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid dehydrogenase, 11 beta type 1, LRRGT00065, MGC13539, OTTHUMP00000034650, SDR26C1, short chain dehydrogenase/reductase family 26C member 1, short chain dehydrogenase/reductase family 26C, member 1, short-chain reductase, short-chain reductase/dehydrogenase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15483, 3290
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P28845, P50172
Gene Symbols: Hsd11b1
Immunogen: Recombinant full length Human HSD11B1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
HSD11B1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Hsd11b1
Gene Alias:
11 beta-hydroxysteroid dehydrogenase type 1, 11beta-HSD type 1, 11-beta-HSD1, 11beta-HSD1, 11beta-HSD-1, 11beta-HSD1A, 11-beta-hydroxysteroid dehydrogenase, 11-beta-hydroxysteroid dehydrogenase 1, 11-beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 1, 11-DH, Corticosteroid 11-beta-dehydrogenase isozyme 1, Corticosteroid 11-beta-dehydrogenase, isozyme 1 (11-DH) (11-beta-hydroxysteroid dehydrogenase 1) (11-beta-HSD1) (11beta-HSD1A), cortocosteroid 11-beta dehydrogenase, CORTRD2, HDL, HSD11, HSD11B, Hsd11b1, HSD11L, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1, hydroxysteroid dehydrogenase, 11 beta type 1, LRRGT00065, MGC13539, OTTHUMP00000034650, SDR26C1, short chain dehydrogenase/reductase family 26C member 1, short chain dehydrogenase/reductase family 26C, member 1, short-chain reductase, short-chain reductase/dehydrogenase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15483, 3290
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P28845, P50172
Gene Symbols:
Hsd11b1
Immunogen:
Recombinant full length Human HSD11B1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CEACAM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CEACAM1
Gene Alias: antigen CD66, ATP-dependent taurocolate-carrier protein, bb-1, BGP, BGP1, BGP-1, BGPI, BGPR, Biliary glycoprotein 1, biliary glycoprotein D, bone gamma-carboxyglutamic acid (Gla) protein, carcinoembryonic antigen 1, carcinoembryonic antigen 7, carcinoembryonic antigen related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), Cc1, C-CAM, C-CAM 105, Ccam1, CD66a, CD66a antigen, Cea1, Cea-1, Cea7, Cea-7, CEACAM1, CEA-related cell adhesion molecule 1, CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin), Cell-CAM 105, ecto-ATPase, GP110, hepatitis virus (MHV-4) susceptibility, hepatitis virus receptor, Hv2, Hv-2, mCEA1, Mhv-1, MHVR, MHV-R, MHVR1, mmCGM1, mmCGM1a, mmCGM2, murine hepatitis virus receptor, osteocalcin, pp120, pp120/ecto-ATPase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26365, 634, 81613
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P13688, P16573, P31809
Gene Symbols: CEACAM1
Immunogen: Recombinant full length Human CEACAM1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CEACAM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CEACAM1
Gene Alias:
antigen CD66, ATP-dependent taurocolate-carrier protein, bb-1, BGP, BGP1, BGP-1, BGPI, BGPR, Biliary glycoprotein 1, biliary glycoprotein D, bone gamma-carboxyglutamic acid (Gla) protein, carcinoembryonic antigen 1, carcinoembryonic antigen 7, carcinoembryonic antigen related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1, carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein), Cc1, C-CAM, C-CAM 105, Ccam1, CD66a, CD66a antigen, Cea1, Cea-1, Cea7, Cea-7, CEACAM1, CEA-related cell adhesion molecule 1, CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin), Cell-CAM 105, ecto-ATPase, GP110, hepatitis virus (MHV-4) susceptibility, hepatitis virus receptor, Hv2, Hv-2, mCEA1, Mhv-1, MHVR, MHV-R, MHVR1, mmCGM1, mmCGM1a, mmCGM2, murine hepatitis virus receptor, osteocalcin, pp120, pp120/ecto-ATPase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26365, 634, 81613
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P13688, P16573, P31809
Gene Symbols:
CEACAM1
Immunogen:
Recombinant full length Human CEACAM1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG