PIPA587250
Granzyme B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587250-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA587250 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
Granzyme B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GZMB
Gene Alias
AI553453, C11, Cathepsin G-like 1, CCP1, CCP-1/C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, Ctla1, Ctla-1, CTSGL1, cytotoxic cell protease 1, cytotoxic serine protease B, Cytotoxic T lymphocyte associated serine esterase 1, cytotoxic T-lymphocyte proteinase 2, cytotoxic T-lymphocyte-associated serine esterase 1, fragmentin, fragmentin 2, fragmentin-2, GLP I, GLP III, GLP-1, granzyme 2, granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), granzyme B(G,H), Granzyme-2, GranzymeB, granzyme-like protein 1, granzyme-like protein I, GRB, GZB, Gzmb, HLP, human lymphocyte protein, Human lymphocyte protein (Hlp), Lymphocyte protease, Natural killer cell protease 1, OTTHUMP00000028189, RNKP-1, SECT, T-cell serine protease 1-3E
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14939, 3002
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.
P04187, P10144
Gene Symbols
GZMB
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 148-247 of human Granzyme B
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Granzyme B is a member of the granzyme serine protease family, and is found in the granules of cytotoxic T cells and NK cells
- Granzyme B has been described as CGL1 (cathepsin G-like-1), a serine protease expressed only in cytotoxic T-lymphocytes after cell activation, and CTLA-1 (cytotoxic T lymphocyte-associated serine esterase 1) based on identification of mRNA in various cytotoxic T cells, but not observed in non-cytotoxic lymphoid cells
- Granzyme B is crucial for the rapid induction of target cell death by apoptosis, induced by interaction with cytotoxic T cells
- The receptor involved in this process has been identified as mannose 6-phosphate receptor which functions as a death receptor for Granzyme B during cytotoxic T cell-induced apoptosis
- Granzyme B enters target cells to cleave caspase-3 and initiate the caspase cascade leading to DNA fragmentation and apoptosis
- Granzyme B can also act through a mitochondrial apoptosis pathway by cleaving the Bid protein
- Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells
- A number of granzymes (A to G) have been isolated and cloned from mouse CTLs and NK cells, however in man, fewer have been cloned and identified.
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Antigen: Granzyme B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GZMB
Gene Alias: AI553453, C11, Cathepsin G-like 1, CCP1, CCP-1/C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, Ctla1, Ctla-1, CTSGL1, cytotoxic cell protease 1, cytotoxic serine protease B, Cytotoxic T lymphocyte associated serine esterase 1, cytotoxic T-lymphocyte proteinase 2, cytotoxic T-lymphocyte-associated serine esterase 1, fragmentin, fragmentin 2, fragmentin-2, GLP I, GLP III, GLP-1, granzyme 2, granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), granzyme B(G,H), Granzyme-2, GranzymeB, granzyme-like protein 1, granzyme-like protein I, GRB, GZB, Gzmb, HLP, human lymphocyte protein, Human lymphocyte protein (Hlp), Lymphocyte protease, Natural killer cell protease 1, OTTHUMP00000028189, RNKP-1, SECT, T-cell serine protease 1-3E
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14939, 3002
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P04187, P10144
Gene Symbols: GZMB
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 148-247 of human Granzyme B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Granzyme B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GZMB
Gene Alias:
AI553453, C11, Cathepsin G-like 1, CCP1, CCP-1/C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, Ctla1, Ctla-1, CTSGL1, cytotoxic cell protease 1, cytotoxic serine protease B, Cytotoxic T lymphocyte associated serine esterase 1, cytotoxic T-lymphocyte proteinase 2, cytotoxic T-lymphocyte-associated serine esterase 1, fragmentin, fragmentin 2, fragmentin-2, GLP I, GLP III, GLP-1, granzyme 2, granzyme B, granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1), granzyme B(G,H), Granzyme-2, GranzymeB, granzyme-like protein 1, granzyme-like protein I, GRB, GZB, Gzmb, HLP, human lymphocyte protein, Human lymphocyte protein (Hlp), Lymphocyte protease, Natural killer cell protease 1, OTTHUMP00000028189, RNKP-1, SECT, T-cell serine protease 1-3E
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14939, 3002
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P04187, P10144
Gene Symbols:
GZMB
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 148-247 of human Granzyme B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: ACAT1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Acat1
Gene Alias: 6330585C21Rik, Acat, Acat1, acetoacetyl Coenzyme A thiolase, acetoacetyl-CoA thiolase, acetyl-Co A acetyltransferase 1 mitochondrial, acetyl-CoA acetyltransferase 1, acetyl-CoA acetyltransferase, mitochondrial, acetyl-Coenzyme A acetyltransferase 1, MAT, mitochondrial acetoacetyl-CoA thiolase, RATACAL, T2, testicular tissue protein Li 198, THIL
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110446, 25014, 38
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P17764, P24752, Q8QZT1
Gene Symbols: Acat1
Immunogen: Recombinant full length Human ACAT1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACAT1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Acat1
Gene Alias:
6330585C21Rik, Acat, Acat1, acetoacetyl Coenzyme A thiolase, acetoacetyl-CoA thiolase, acetyl-Co A acetyltransferase 1 mitochondrial, acetyl-CoA acetyltransferase 1, acetyl-CoA acetyltransferase, mitochondrial, acetyl-Coenzyme A acetyltransferase 1, MAT, mitochondrial acetoacetyl-CoA thiolase, RATACAL, T2, testicular tissue protein Li 198, THIL
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110446, 25014, 38
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P17764, P24752, Q8QZT1
Gene Symbols:
Acat1
Immunogen:
Recombinant full length Human ACAT1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Cdc34
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDC34
Gene Alias: (E3-independent) E2 ubiquitin-conjugating enzyme R1, AI327276, CDC34, cell division cycle 34, cell division cycle 34 homolog, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, serine protease, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme Cdc34, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 216150, 997
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.: P49427, Q8CFI2
Gene Symbols: CDC34
Immunogen: Recombinant full length Human CDC34.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Cdc34
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDC34
Gene Alias:
(E3-independent) E2 ubiquitin-conjugating enzyme R1, AI327276, CDC34, cell division cycle 34, cell division cycle 34 homolog, E2 ubiquitin-conjugating enzyme R1, E2-CDC34, serine protease, UBC3, UBCH3, UBE2R1, ubiquitin carrier protein, ubiquitin conjugating enzyme E2 R1, ubiquitin-conjugating enzyme Cdc34, ubiquitin-conjugating enzyme E2 R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
216150, 997
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide
Gene Accession No.:
P49427, Q8CFI2
Gene Symbols:
CDC34
Immunogen:
Recombinant full length Human CDC34.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: MYL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYL2
Gene Alias: cardiac myosin light chain 2, cardiac myosin light chain-2, cardiac ventricular myosin light chain 2, CMH10, DKFZp779C0562, hypothetical protein LOC677750, Mlc2, MLC-2, mLc2b, MLC-2s/v, MLC2V, MLC-2v, myl2, myl2b, Mylpc, myosin light chain 2, myosin light chain 2, slow skeletal/ventricular muscle isoform, myosin light chain 2V, myosin light chain phosphatase, myosin light chain, phosphorylatable, cardiac ventricles, myosin light chain-2, myosin regulatory light chain 2, ventricular/cardiac muscle isoform, myosin regulatory light chain 2b, myosin regulatory light chain ventricular isoform, myosin, light chain 2, regulatory, cardiac, slow, myosin, light chain 2b, regulatory, cardiac, slow, myosin, light polypeptide 2, regulatory, cardiac, slow, myosin, light polypeptide 2b, regulatory, cardiac, slow, regulatory light chain of myosin, RLC of myosin, slow cardiac myosin regulatory light chain 2, ventricular myosin light chain 2, ventricular myosin regulatory light chain, zgc:136848
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17906, 4633
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P10916, P51667
Gene Symbols: MYL2
Immunogen: Recombinant full length Human Myosin light chain 2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MYL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MYL2
Gene Alias:
cardiac myosin light chain 2, cardiac myosin light chain-2, cardiac ventricular myosin light chain 2, CMH10, DKFZp779C0562, hypothetical protein LOC677750, Mlc2, MLC-2, mLc2b, MLC-2s/v, MLC2V, MLC-2v, myl2, myl2b, Mylpc, myosin light chain 2, myosin light chain 2, slow skeletal/ventricular muscle isoform, myosin light chain 2V, myosin light chain phosphatase, myosin light chain, phosphorylatable, cardiac ventricles, myosin light chain-2, myosin regulatory light chain 2, ventricular/cardiac muscle isoform, myosin regulatory light chain 2b, myosin regulatory light chain ventricular isoform, myosin, light chain 2, regulatory, cardiac, slow, myosin, light chain 2b, regulatory, cardiac, slow, myosin, light polypeptide 2, regulatory, cardiac, slow, myosin, light polypeptide 2b, regulatory, cardiac, slow, regulatory light chain of myosin, RLC of myosin, slow cardiac myosin regulatory light chain 2, ventricular myosin light chain 2, ventricular myosin regulatory light chain, zgc:136848
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17906, 4633
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P10916, P51667
Gene Symbols:
MYL2
Immunogen:
Recombinant full length Human Myosin light chain 2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG