PIPA587417

CRM1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587417-Each-of-1 In Stock ₹ 45,646.26

PIPA587417 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

CRM1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

XPO1

Gene Alias

AA420417, chromosome region maintenance 1 homolog, chromosome region maintenance 1 protein homolog, CRM1, emb, Exp1, exportin 1, exportin 1 (CRM1 homolog, yeast), exportin 1 (CRM1, yeast, homolog), exportin 1, CRM1 homolog, exportin 1, CRM1 homolog (yeast), exportin-1, exportin-1 (required for chromosome region maintenance), Xpo1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

103573, 7514

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.85 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

O14980, Q6P5F9

Gene Symbols

XPO1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 964-1064 of human CRM1/CRM1/XPO1 (NP_0033911)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA596391

--

Img

Thermo Scientific

PIPA597624

--

Img

Thermo Scientific

PIPA592446

--

Img

Thermo Scientific

PIPA597297

--

Img

Novus Biologicals

NB516989

--

Img

Novus Biologicals

NB225279

--

Img

Thermo Scientific

PIPA595770

--

Img

Thermo Scientific

PIPA536250

--

Description

  • Positive Samples: U-87MG, B-cell, Mouse liver; Cellular Location: Cajal body, Cytoplasm, Nucleus, nucleolus, nucleoplasm Immunogen sequence: PGNPVNNQIF LQEYVANLLK SAFPHLQDAQ VKLFVTGLFS LNQDIPAFKE HLRDFLVQIK EFAGEDTSDL FLEEREIALR QADEEKHKRQ MSVPGIFNPH E Exportin - 1 (XPO1) mediates the nuclear export of cellular proteins bearing a leucine-rich nuclear export signal (NES) and RNAs
  • In the nucleus, in association with RANBP3, XPO1 binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP)
  • Docking of this complex to the nuclear pore complex is mediated through binding to nucleoproteins
  • Upon transit of a nuclear complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP cause release of the cargo from the export receptor
  • The directionality of the nuclear export is thought to be conferred by an asymmetric distribution of the GTP and GDP bound forms of Ran between the cytoplasm and nucleus.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA587417

--


Antigen:
CRM1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XPO1

Gene Alias:
AA420417, chromosome region maintenance 1 homolog, chromosome region maintenance 1 protein homolog, CRM1, emb, Exp1, exportin 1, exportin 1 (CRM1 homolog, yeast), exportin 1 (CRM1, yeast, homolog), exportin 1, CRM1 homolog, exportin 1, CRM1 homolog (yeast), exportin-1, exportin-1 (required for chromosome region maintenance), Xpo1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
103573, 7514

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.85 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O14980, Q6P5F9

Gene Symbols:
XPO1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 964-1064 of human CRM1/CRM1/XPO1 (NP_0033911)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587421

--


Antigen:
CD79a

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD79A

Gene Alias:
B-cell antigen receptor, B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein alpha chain-like, CD79, CD79a, CD79A antigen (immunoglobulin-associated alpha), CD79a molecule, CD79a molecule, immunoglobulin-associated alpha, CD79A protein, CD79-alpha protein, EGK_10665, Ig alpha, IGA, Igalpha, ig-alpha, immunoglobulin-associated alpha, LOC100913063, Ly54, Ly-54, MB1, MB-1, MB-1 membrane glycoprotein, Membrane-bound immunoglobulin-associated protein, surface IgM-associated protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100913063, 12518, 973

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.71 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P11911, P11912

Gene Symbols:
CD79A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 165-225 of human CD79a (NP_0017741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587422

--


Antigen:
CD44

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD44

Gene Alias:
AU023126, AW121933, AW146109, Bovine CD44, CD44, CD44 antigen, CD44 antigen-like protein, CD44 molecule, CD44 molecule (Indian blood group), CD44 protein, CD44 variant, CD44A, CD44-like protein, CDW44, cell surface glycoprotein CD44, Cell surface glycoprotein CD44 (hyaluronate binding protein), cell-surface glycoprotein, chondroitin sulfate proteoglycan 8, CSPG8, ECMRIII, ECMR-III, Epican, extracellular matrix receptor III, extracellular matrix receptor-III, GP90 lymphocyte homing/adhesion receptor, HCELL, hematopoietic cell E- and L-selectin ligand, heparan sulfate proteoglycan, HERMES, Hermes antigen, homing function and Indian blood group system, HUTCH-I, hyaluronan receptor, Hyaluronate receptor, IN, LHR, Ly-24, lymphocyte antigen 24, lymphocyte surface antigen precursor CD44, MC56, MDU2, MDU3, METAA, MIC4, PGP I, Pgp1, PGP-1, PGPI, PGP-I, Phagocytic glycoprotein 1, phagocytic glycoprotein I, putative Bos taurus CD44, RHAMM, sCD 44, sCD44, soluble CD 44, soluble CD44

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12505, 960

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
0.8 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P15379, P16070

Gene Symbols:
CD44

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 346-385 of CD44 (NP_0006013)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587423

--


Antigen:
MDM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM2

Gene Alias:
1700007J15Rik, AA415488, ACTFS, double minute 2, double minute 2 protein, double minute 2, human homolog of, p53-binding protein, E3 ubiquitin-protein ligase Mdm2, Hdm2, HDMX, HGNC:6973, human homolog of, MDM2, Mdm-2, MDM2 oncogene, E3 ubiquitin protein ligase, Mdm2 p53 binding protein homolog, MDM2 proto-oncogene, MDM2 proto-oncogene, E3 ubiquitin protein ligase, MDM2 variant FB28, Mdm2, p53 E3 ubiquitin protein ligase homolog, Mdm2, transformed 3T3 cell double minute 2, p53 binding protein, MGC5370, MGC71221, oncoprotein Mdm2, OTTHUMP00000183490, OTTHUMP00000183492, OTTHUMP00000183494, OTTHUMP00000183495, OTTHUMP00000183496, OTTHUMP00000183497, p53 E3 ubiquitin protein ligase, p53-binding protein Mdm2, RING-type E3 ubiquitin transferase Mdm2, transformed mouse 3T3 cell double minute 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17246, 4193

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot, Immunohistochemistry, Western Blot

Concentration:
0.49 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P23804, Q00987

Gene Symbols:
MDM2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 231-330 of human MDM2 (NP_0013549191)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG