PIPA587455

NOTCH2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587455-Each-of-1 In Stock ₹ 44,705.10

PIPA587455 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NOTCH2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NOTCH2

Gene Alias

AGS2, AI853703, HJCYS, hN2, Motch B, N2, N2ECD, N2ICD, Neurogenic locus notch homolog protein 2, notch 2, Notch 2 extracellular truncation, Notch 2 intracellular domain, notch gene homolog 2, Notch homolog 2, notch receptor 2, Notch2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18129, 4853

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.16 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O35516, Q04721

Gene Symbols

NOTCH2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2242-2471 of human NOTCH2 (NP_0777192)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SRLHPVPVPA DWMNRMEVNE TQYNEMFGMV LAPAEGTHPG IAPQSRPPEG KHITTPREPL PPIVTFQLIP KGSIAQPAGA PQPQSTCPPA VAGPLPTMYQ IPEMARLPSV AFPTAMMPQQ DGQVAQTILP AYHPFPASVG KYPTPPSQHS YASSNAAERT PSHSGHLQGE HPYLTPSPES PDQWSSSSPH SASDWSDVTT SPTPGGAGGG QRGPGTHMSE PPHNNMQVYA; Positive Samples: 293T, LO2, HeLa; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Single-pass type I membrane protein Neurogenic locus notch homolog protein 2 (NOTCH2) is a highly conserved Notch signaling pathway protein
  • NOTCH2 is a type 1 transmembrane protein with an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types
  • NOTCH2 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination
  • Defects in NOTCH2 are the cause of Alagille syndrome type 2 (ALGS2)
  • Alagille syndrome is an autosomal dominant multisystem disorder defined clinically by hepatic bile duct paucity and cholestasis in association with cardiac, skeletal, and ophthalmologic manifestations
  • There are characteristic facial features and less frequent clinical involvement of the renal and vascular systems.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA587455

--


Antigen:
NOTCH2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NOTCH2

Gene Alias:
AGS2, AI853703, HJCYS, hN2, Motch B, N2, N2ECD, N2ICD, Neurogenic locus notch homolog protein 2, notch 2, Notch 2 extracellular truncation, Notch 2 intracellular domain, notch gene homolog 2, Notch homolog 2, notch receptor 2, Notch2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18129, 4853

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.16 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O35516, Q04721

Gene Symbols:
NOTCH2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2242-2471 of human NOTCH2 (NP_0777192)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587456

--


Antigen:
eIF3a

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EIF3A

Gene Alias:
150/170, A830012B05Rik, Centrosomin, centrosomin homolog, Csma, cytoplasmic protein p167, Eif3, eIF3 p167, eIF3 p180, eIF3 p185, EIF3, p180 subunit, eIF3a, eIF3a {ECO:0000255, eIF3-p170, EIF3S10, eIF-3-theta, eIF3-theta, eIF-3-theta {ECO:0000255, eukaryotic translation initiation factor 3 subunit 10, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN), eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255, eukaryotic translation initiation factor 3 subunit A, eukaryotic translation initiation factor 3 subunit A {ECO:0000255, eukaryotic translation initiation factor 3, subunit 10 (theta), eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD), eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD), eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, eukaryotic translation initiation factor 3, subunit 10, 170kD, eukaryotic translation initi

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13669, 8661

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot, Western Blot

Concentration:
0.68 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P23116, Q14152

Gene Symbols:
EIF3A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_0037411)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587457

--


Antigen:
SMAD6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SMAD6

Gene Alias:
AOVD2, b2b390Clo, HsT17432, MAD homolog 6, mad homolog 7, Madh6, Madh7, Mothers against decapentaplegic homolog 6, mothers against decapentaplegic, drosophila, homolog of, 6, mothers against DPP homolog 6, Msmad6, SMAD, SMAD 6, SMAD family member 6, SMAD SMAD, SMAD, mothers against DPP homolog 6, SMAD6

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17130, 367100, 4091

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.33 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O35182, O43541

Gene Symbols:
SMAD6

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human Smad6 (NP_0055763)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA587458

--


Antigen:
MAX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAX

Gene Alias:
AA960152, AI875693, bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8, Class D basic helix-loop-helix protein 4, Delta-Max, Max, Max protein, MGC10775, MGC11225, MGC18164, MGC34679, MGC36767, MYC associated factor X, myc-associated factor X, Myc-binding novel HLH/LZ protein, Myn, orf1, Protein max, protein myn

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4149

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.54 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P61244

Gene Symbols:
MAX

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human MAX (NP_0023733)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG