PIPA587551

Synaptotagmin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587551-Each-of-1 In Stock ₹ 44,705.10

PIPA587551 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Synaptotagmin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Syt1

Gene Alias

AW124717, DKFZp781D2042, FLJ42519, G630098F17Rik, P65, SV DKFZp781D2042, SV SYT, svp65, Syb1, synaptotagmin 1, synaptotagmin 1 L homeolog, synaptotagmin 2, synaptotagmin I, synaptotagmin I protein, synaptotagmin I variant b, Synaptotagmin II, Synaptotagmin XI, synaptotagmin-1, Synaptotagmin-2, SYT, Syt1, syt1.L, SYT2, SytI, SytII, XELAEV_18022019mg

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20979, 25716, 6857

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.51 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P21579, P21707, P46096

Gene Symbols

Syt1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 84-157 of human SYT1 (NP_0056301)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: LFKKKNKKKG KEKGGKNAIN MKDVKDLGKT MKDQALKDDD AETGLTDGEE KEEPKEEEKL GKLQYSLDYD FQNN Positive Samples: SW620, A673; Cellular Location: Cytoplasm, Cytoplasmic vesicle, Single-pass membrane protein, chromaffin granule membrane, secretory vesicle, synaptic vesicle membrane Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release
  • Studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane
  • It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size
  • Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse
  • Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
  • A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported
  • Synaptotagmin 1 can also bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2
  • Diseases associated with the dysfunction of Synaptotagmin 1 include food-borne botulism and infant botulism.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA587551

--


Antigen:
Synaptotagmin 1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717, DKFZp781D2042, FLJ42519, G630098F17Rik, P65, SV DKFZp781D2042, SV SYT, svp65, Syb1, synaptotagmin 1, synaptotagmin 1 L homeolog, synaptotagmin 2, synaptotagmin I, synaptotagmin I protein, synaptotagmin I variant b, Synaptotagmin II, Synaptotagmin XI, synaptotagmin-1, Synaptotagmin-2, SYT, Syt1, syt1.L, SYT2, SytI, SytII, XELAEV_18022019mg

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20979, 25716, 6857

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P21579, P21707, P46096

Gene Symbols:
Syt1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 84-157 of human SYT1 (NP_0056301)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587557

--


Antigen:
GEN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GEN1

Gene Alias:
5830483C08Rik, Flap endonuclease GEN homolog 1, Gen, Gen endonuclease homolog 1, Gen homolog 1, endonuclease, Gen homolog 1, endonuclease (Drosophila), GEN1, GEN1 Holliday junction 5' flap endonuclease, GEN1, Holliday junction 5' flap endonuclease, Holliday junction resolvase, RGD1559792

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
209334, 348654

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q17RS7, Q8BMI4

Gene Symbols:
GEN1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 669-908 of human GEN1 (NP_8724313)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587559

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Antigen:
GNG7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Gng7

Gene Alias:
AI840417, G protein subunit gamma 7, GNG7, Gngt7, guanine nucleotide binding protein (G protein), gamma 7, guanine nucleotide binding protein (G protein), gamma 7 subunit, guanine nucleotide binding protein, gamma 7, guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14708, 58979

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P43425, Q61016

Gene Symbols:
Gng7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human GNG7 (NP_4430791)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587560

--


Antigen:
PLXNB1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Plxnb1

Gene Alias:
2900002G15Rik, AU042020, Kiaa0407, mKIAA0407, plexin 1, plexin 5, plexin B1, plexin-A1, PLEXIN-B1, PLXN5, Plxnb1, Semaphorin receptor SEP, SEP

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
235611, 5364

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O43157, Q8CJH3

Gene Symbols:
Plxnb1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 250-470 of human PLXNB1 (NP_0026642)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG