PIPA587648
LAIR1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587648-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587648 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
LAIR1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LAIR1
Gene Alias
5133400O11Rik, BB115266, CD305, D7Bwg0421e, immunoglobulin heavy chain variable region, Lair1, Lair-1, leukocyte associated immunoglobulin like receptor 1, leukocyte-associated Ig-like receptor 1, leukocyte-associated Ig-like receptor-1, leukocyte-associated immunoglobulin-like receptor 1, rLAIR1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3903
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.61 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q6GTX8
Gene Symbols
LAIR1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 22-163 of human LAIR1 (NP_0022782)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: B-cell, Jurkat, HL-60, Raji, Mouse brain, Mouse liver, Mouse lung, Rat liver; Cellular Location: Cell membrane, Single-pass type I membrane protein Immunogen sequence: QEEDLPRPSI SAEPGTVIPL GSHVTFVCRG PVGVQTFRLE RDSRSTYNDT EDVSQASPSE SEARFRIDSV REGNAGLYRC IYYKPPKWSE QSDYLELLVK ESSGGPDSPD TEPGSSAGPT QRPSDNSHNE HAPASQGLKA EH LAIR1 (CD305) functions as an inhibitory receptor that plays a constitutive negative regulatory role on cytolytic function of natural killer (NK) cells, B-cells and T-cells
- Activation by Tyr phosphorylation results in recruitment and activation of the phosphatases PTPN6 and PTPN11
- It also reduces the increase of intracellular calcium evoked by B-cell receptor ligation
- May also play its inhibitory role independently of SH2-containing phosphatases
- Modulates cytokine production in CD4+ T-cells, down-regulating IL2 and IFNG production while inducing secretion of transforming growth factor beta
- Down-regulates also IgG and IgE production in B-cells as well as IL8, IL10 and TNF secretion
- Inhibits proliferation and induces apoptosis in myeloid leukemia cell lines as well as prevents nuclear translocation of NF-kappa-B p65 subunit/RELA and phosphorylation of I-kappa-B alpha/CHUK in these cells
- Inhibits the differentiation of peripheral blood precursors towards dendritic cells.
Compare Similar Items
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Antigen: LAIR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LAIR1
Gene Alias: 5133400O11Rik, BB115266, CD305, D7Bwg0421e, immunoglobulin heavy chain variable region, Lair1, Lair-1, leukocyte associated immunoglobulin like receptor 1, leukocyte-associated Ig-like receptor 1, leukocyte-associated Ig-like receptor-1, leukocyte-associated immunoglobulin-like receptor 1, rLAIR1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3903
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.61 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q6GTX8
Gene Symbols: LAIR1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-163 of human LAIR1 (NP_0022782)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
LAIR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LAIR1
Gene Alias:
5133400O11Rik, BB115266, CD305, D7Bwg0421e, immunoglobulin heavy chain variable region, Lair1, Lair-1, leukocyte associated immunoglobulin like receptor 1, leukocyte-associated Ig-like receptor 1, leukocyte-associated Ig-like receptor-1, leukocyte-associated immunoglobulin-like receptor 1, rLAIR1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3903
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.61 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q6GTX8
Gene Symbols:
LAIR1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-163 of human LAIR1 (NP_0022782)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NDUFA10
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NDUFA10
Gene Alias: 2900053E13Rik, CI-42k, CI-42KD, complex I 42kDa subunit, complex I-42kD, FLJ21923, MGC5103, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, NADH:ubiquinone oxidoreductase subunit A10, NADH-ubiquinone oxidoreductase 42 kDa subunit, Ndufa10, ndufa10l
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4705, 67273, 678759
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.97 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O95299, Q99LC3
Gene Symbols: NDUFA10
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human NDUFA10 (NP_0045351)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
NDUFA10
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NDUFA10
Gene Alias:
2900053E13Rik, CI-42k, CI-42KD, complex I 42kDa subunit, complex I-42kD, FLJ21923, MGC5103, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial, NADH:ubiquinone oxidoreductase subunit A10, NADH-ubiquinone oxidoreductase 42 kDa subunit, Ndufa10, ndufa10l
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4705, 67273, 678759
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.97 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O95299, Q99LC3
Gene Symbols:
NDUFA10
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 36-300 of human NDUFA10 (NP_0045351)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PRKAR1B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PRKAR1B
Gene Alias: AI385716, cAMP dependent protein kinase, subunit type 1 beta, cAMP dependent regulatory type I beta subunit transcript 2, cAMP dependent regulatory type I beta subunit transcript 3, cAMP dependent regulatory type I beta subunit transcript 4, cAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1, PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta, protein kinase, cAMP dependent regulatory, type I beta, protein kinase, cAMP dependent regulatory, type I, beta, protein kinase, cAMP-dependent, regulatory subunit type I beta, protein kinase, cAMP-dependent, regulatory, type I, beta, RGD1563094, RIbeta
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19085, 25521, 5575
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P12849, P31321, P81377
Gene Symbols: PRKAR1B
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-290 of human PRKAR1B (NP_0027261)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PRKAR1B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PRKAR1B
Gene Alias:
AI385716, cAMP dependent protein kinase, subunit type 1 beta, cAMP dependent regulatory type I beta subunit transcript 2, cAMP dependent regulatory type I beta subunit transcript 3, cAMP dependent regulatory type I beta subunit transcript 4, cAMP-dependent protein kinase type I-beta regulatory subunit, PRKAR1, PRKAR1B, protein kinase cAMP-dependent type I regulatory subunit beta, protein kinase, cAMP dependent regulatory, type I beta, protein kinase, cAMP dependent regulatory, type I, beta, protein kinase, cAMP-dependent, regulatory subunit type I beta, protein kinase, cAMP-dependent, regulatory, type I, beta, RGD1563094, RIbeta
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19085, 25521, 5575
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P12849, P31321, P81377
Gene Symbols:
PRKAR1B
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-290 of human PRKAR1B (NP_0027261)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: IKAP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ELP1
Gene Alias: 3110040G09Rik, 6030413P05, C78473, DKFZp781H1425, DYS, elongator acetyltransferase complex subunit 1, elongator complex protein 1, Elp1, FD, FLJ12497, IKAP, IkappaB kinase complex-associated protein, IKBKAP, IKI3, IKK complex-associated protein, IKK-complex-associated protein IKAP, inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein, inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein, p150, RP11-3J11.4, TOT1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 140934, 230233, 8518
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.94 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O95163, Q7TT37, Q8VHU4
Gene Symbols: ELP1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1093-1332 of human IKBKAP (NP_0036312)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IKAP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ELP1
Gene Alias:
3110040G09Rik, 6030413P05, C78473, DKFZp781H1425, DYS, elongator acetyltransferase complex subunit 1, elongator complex protein 1, Elp1, FD, FLJ12497, IKAP, IkappaB kinase complex-associated protein, IKBKAP, IKI3, IKK complex-associated protein, IKK-complex-associated protein IKAP, inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein, inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein, p150, RP11-3J11.4, TOT1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
140934, 230233, 8518
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.94 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O95163, Q7TT37, Q8VHU4
Gene Symbols:
ELP1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1093-1332 of human IKBKAP (NP_0036312)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG