PIPA588251
TLR3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588251-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588251 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
TLR3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TLR3
Gene Alias
AI957183, CD283, IIAE2, TLR 3, TLR3, TLR-3, toll like receptor 3, toll-like receptor 3, toll-like receptor 3 variant 1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
142980, 364594, 7098
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.41 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
O15455, Q99MB1
Gene Symbols
TLR3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human TLR3 (NP_0032561)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: A-549, LO2, U-87MG; Cellular Location: Early endosome, Endoplasmic reticulum membrane, Endosome membrane, Single-pass type I membrane protein Immunogen sequence: SPFQPLRNLT ILDLSNNNIA NINDDMLEGL EKLEILDLQH NNLARLWKHA NPGGPIYFLK GLSHLHILNL ESNGFDEIPV EVFKDLFELK IIDLGLNNLN TLPASVFNNQ VSLKSLNLQK NLITSVEKKV FGPAFRNLTE LDMRFNPFDC TCESIAWFVN WINETHTNIP ELSSHYLCNT PPHYHGFPVR LFDTSSCKDS A TLR3 (Toll-like receptor 3, CD283) is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity
- TLRs are highly conserved from drosophila to humans and share structural and functional similarities
- TLRs recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity
- The various TLRs exhibit different patterns of expression
- TLR3 is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes
- TLR3 recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons
- Further, TLR3 may play a role in host defense against viruses, and the use of alternative polyadenylation sites to generate different length transcripts has been noted for the TLR3 gene
- Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans
- The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition
- TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway
- TLR3 is the only human TLR which does not utilize MyD88 as an adaptor molecule instead utilizing TRIF in a signaling path which results in downstream activation of IRF-3 and NF-kB
- TLR3 activation leads not only to Type I interferon induction but also to other inflammatory cytokines which result in DC maturation
- TLR3 is known to recognize viral double-stranded (ds) RNA, a molecular pattern associated with viral infection
- Recently it has been shown to recognize viruses such as Influenza A and West Nile Virus and can mediate entry of at least West Nile Virus.
Compare Similar Items
Show Difference
Antigen: TLR3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TLR3
Gene Alias: AI957183, CD283, IIAE2, TLR 3, TLR3, TLR-3, toll like receptor 3, toll-like receptor 3, toll-like receptor 3 variant 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 142980, 364594, 7098
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.41 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O15455, Q99MB1
Gene Symbols: TLR3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human TLR3 (NP_0032561)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TLR3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TLR3
Gene Alias:
AI957183, CD283, IIAE2, TLR 3, TLR3, TLR-3, toll like receptor 3, toll-like receptor 3, toll-like receptor 3 variant 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
142980, 364594, 7098
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.41 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O15455, Q99MB1
Gene Symbols:
TLR3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-700 of human TLR3 (NP_0032561)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: STAT5 alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT5A
Gene Alias: AA959963, mammary gland factor, mammary gland factor STAT5A, mammary gland factor, transcription factor, Mgf, Mpf, signal transducer and activator of transcription 5, signal transducer and activator of transcription 5a, signal transducer and activator of transcription factor 5A, STAT, STAT5, STAT5A, STAT5A, Mammary Gland Factor, STAT5A/MGF, STAT5B, STATA5
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20850, 6776
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.09 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P42229, P42230
Gene Symbols: STAT5A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT5A (NP_001275647.1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
STAT5 alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT5A
Gene Alias:
AA959963, mammary gland factor, mammary gland factor STAT5A, mammary gland factor, transcription factor, Mgf, Mpf, signal transducer and activator of transcription 5, signal transducer and activator of transcription 5a, signal transducer and activator of transcription factor 5A, STAT, STAT5, STAT5A, STAT5A, Mammary Gland Factor, STAT5A/MGF, STAT5B, STATA5
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20850, 6776
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.09 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P42229, P42230
Gene Symbols:
STAT5A
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT5A (NP_001275647.1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RAB5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RAB5A
Gene Alias: 2410015H04Rik, AI663973, AU021172, nnyRab5a, Rab 5, Rab 5A, RAB5, RAB5A, RAB5A, member RAS oncogene family, Ras related protein, RAS-associated protein RAB5A, ras-related protein Rab-5A, Small GTP-binding protein rab5
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 271457, 5868, 64633
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.29 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: M0RC99, P20339, Q9CQD1
Gene Symbols: RAB5A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human RAB5A (NP_0041532)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RAB5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RAB5A
Gene Alias:
2410015H04Rik, AI663973, AU021172, nnyRab5a, Rab 5, Rab 5A, RAB5, RAB5A, RAB5A, member RAS oncogene family, Ras related protein, RAS-associated protein RAB5A, ras-related protein Rab-5A, Small GTP-binding protein rab5
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
271457, 5868, 64633
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.29 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
M0RC99, P20339, Q9CQD1
Gene Symbols:
RAB5A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human RAB5A (NP_0041532)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ISG15
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ISG15
Gene Alias: G1P2, hUCRP, IFI15, IGI15, IMD38, interferon, alpha-inducible protein, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 15 kDa protein, interferon-induced 15-KDa protein, interferon-induced 17 kDa protein, interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein (15 kDa), interferon-stimulated protein 15, interferon-stimulated protein, 15 kDa, IP17, Irfp, Isg15, ISG15 ubiquitin like modifier, ISG15 ubiquitin-like modifier, ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 298693, 9636
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.74 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P05161
Gene Symbols: ISG15
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_0050921)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ISG15
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ISG15
Gene Alias:
G1P2, hUCRP, IFI15, IGI15, IMD38, interferon, alpha-inducible protein, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 15 kDa protein, interferon-induced 15-KDa protein, interferon-induced 17 kDa protein, interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein (15 kDa), interferon-stimulated protein 15, interferon-stimulated protein, 15 kDa, IP17, Irfp, Isg15, ISG15 ubiquitin like modifier, ISG15 ubiquitin-like modifier, ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
298693, 9636
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.74 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P05161
Gene Symbols:
ISG15
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_0050921)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat, Rat
Product Type:
Antibody
Isotype:
IgG