PIPA588077

IRF3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588077-Each-of-1 In Stock ₹ 49,582.02

PIPA588077 - Each of 1

₹ 49,582.02

In Stock

Quantity

1

Base Price: ₹ 49,582.02

GST (18%): ₹ 8,924.764

Total Price: ₹ 58,506.784

Antigen

IRF3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IRF3

Gene Alias

C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

292892, 3661, 54131

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1.29 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P70671, Q14653

Gene Symbols

IRF3

Immunogen

A recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human IRF3.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PHDPHKIYEF VNSGVGDFSQ PDTSPDTNGG GSTSDTQEDI LDELLGNMVL APLPDPGPPS LAVAPEPCPQ PLRSPSLDNP TPFPNLGPSE NPLKRLLVPG E Positive Samples: 293T, HeLa, Jurkat, HepG2; Cellular Location: Cytoplasm, Nucleus IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
  • It plays a critical role in the innate immune response against DNA and RNA viruses
  • IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
  • It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
  • IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
  • It is phosphorylated by IKBKE and TBK1 kinases
  • This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
  • Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA588077

--


Antigen:
IRF3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRF3

Gene Alias:
C920001K05Rik, IIAE7, Interferon regulatory factor 3, IRF3, IRF-3, IRF3 (phospho S386), IRF3 (pS386), IRF3 (pSer386), IRF3 phospho, IRF3 phospho S386, IRF3 phospho Ser386, phospho IRF3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
292892, 3661, 54131

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P70671, Q14653

Gene Symbols:
IRF3

Immunogen:
A recombinant fusion protein containing a sequence corresponding to amino acids 100-200 of human IRF3.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA588078

--


Antigen:
IL-1 beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IL1B

Gene Alias:
catabolin, cytokine, Hematopoietin 1 (H1), IFN beta inducing factor, il 1b, IL 1β, IL-1, IL1 B, IL-1 beta, IL-1 precursor, IL1B, IL-1B, IL1B1, IL1beta, IL-1beta, IL1-BETA, IL1F2, IL1β, ILN, Interleukin, interleukin 1 beta, Interleukin 1 beta precursor, interleukin 1, beta, interleukin 1, beta 1, interleukin 1-beta, interleukin*1*beta, Interleukin1 beta, interleukin-1 beta, interleukin-1 beta precursor, interleukin-1 beta precursor (AA -113 to 153), interleukin-1 beta proprotein, interleukin-1b, interleukin-1beta, interleukin-beta, LAF, lymphocyte proliferation-potentiating factor, Osteoclast activating factor (OAF), preinterleukin 1 beta, Pro interleukin 1 beta, prointerleukin-1 beta, pro-interleukin-1-beta

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16176, 24494, 3553

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.97 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P01584, P10749, Q63264

Gene Symbols:
IL1B

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-269 of human IL1beta (NP_0005671)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA588080

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Antigen:
DAZL

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DAZL

Gene Alias:
DAZ homolog, DAZH, DAZL, DAZL1, Dazla, Daz-like, DAZ-like autosomal, deleted in azoospermia like, deleted in azoospermia protein 3, deleted in azoospermia-like, Deleted in azoospermia-like 1, deleted in azoospermia-like protein, germline specific RNA binding protein, HGNC:2685, MGC26406, spermatogenesis gene on the Y-like autosomal, SPGYLA, SPGY-like-autosomal, testis secretory sperm-binding protein Li 204a, Tpx2, Tpx-2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13164, 1618

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.99 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q64368, Q92904

Gene Symbols:
DAZL

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_0013422)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA588082

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Antigen:
MRP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCC1

Gene Alias:
ABC29, ABCC, Abcc1, Abcc1a, Abcc1b, ATP binding cassette subfamily C member 1, ATP-binding cassette sub-family C ( CFTR/MRP) member 1a, ATP-binding cassette sub-family C member 1, ATP-binding cassette transporter variant ABCC1delta-ex13, ATP-binding cassette transporter variant ABCC1delta-ex13&14, ATP-binding cassette transporter variant ABCC1delta-ex25, ATP-binding cassette transporter variant ABCC1delta-ex25&26, ATP-binding cassette, subfamily C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1, ATP-binding cassette, sub-family C (CFTR/MRP), member 1a, ATP-binding cassette, sub-family C (CFTR/MRP), member 1b, Avcc1a, DKFZp686N04233, DKFZp781G125, Glutathione-S-conjugate-translocating ATPase ABCC1, GS-X, leuk, leukotriene C(4) transporter, LTC4 transporter, Mdrap, MRP, Mrp1, multidrug resistance protein 1, multidrug resistance-associated protein 1, multiple drug resistance-associated protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4363

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P33527

Gene Symbols:
ABCC1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 850-960 of human MRP1/ABCC1 (NP_0049872)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG