PIPA588252

STAT5 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588252-Each-of-1 In Stock ₹ 44,705.10

PIPA588252 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

STAT5 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

STAT5A

Gene Alias

AA959963, mammary gland factor, mammary gland factor STAT5A, mammary gland factor, transcription factor, Mgf, Mpf, signal transducer and activator of transcription 5, signal transducer and activator of transcription 5a, signal transducer and activator of transcription factor 5A, STAT, STAT5, STAT5A, STAT5A, Mammary Gland Factor, STAT5A/MGF, STAT5B, STATA5

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20850, 6776

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

2.09 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P42229, P42230

Gene Symbols

STAT5A

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT5A (NP_001275647.1).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: Mouse heart, Mouse lung, Mouse liver, Rat heart, Rat lung; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: DFSIRSLADR LGDLSYLIYV FPDRPKDEVF SKYYTPVLAK AVDGYVKPQI KQVVPEFVNA SADAGGSSAT YMDQAPSPAV CPQAPYNMYP QNPDHVLDQD G STAT5 alpha is a member of the STAT family of transcription factors
  • In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators
  • STAT5 alpha is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones
  • Activation of STAT5 alpha in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis
  • The mouse counterpart of STAT5 alpha is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this protein in cells
  • STAT5 alpha, along with STAT5 beta, were identified in mouse
  • The amino acid sequences of STAT5 alpha and STAT5 beta show 96% sequence similarity, and both proteins are co expressed in most tissues in virgin and lactating mice
  • However, differential accumulation of STAT5 alpha and STAT5 beta mRNA has been reported for both muscle and mammary tissue
  • STAT5 alpha is critically involved in a variety of physiological functions, including reproduction, lactation, immune function and somatic growth.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA588252

--


Antigen:
STAT5 alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STAT5A

Gene Alias:
AA959963, mammary gland factor, mammary gland factor STAT5A, mammary gland factor, transcription factor, Mgf, Mpf, signal transducer and activator of transcription 5, signal transducer and activator of transcription 5a, signal transducer and activator of transcription factor 5A, STAT, STAT5, STAT5A, STAT5A, Mammary Gland Factor, STAT5A/MGF, STAT5B, STATA5

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20850, 6776

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.09 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P42229, P42230

Gene Symbols:
STAT5A

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT5A (NP_001275647.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA588260

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Antigen:
RAB5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAB5A

Gene Alias:
2410015H04Rik, AI663973, AU021172, nnyRab5a, Rab 5, Rab 5A, RAB5, RAB5A, RAB5A, member RAS oncogene family, Ras related protein, RAS-associated protein RAB5A, ras-related protein Rab-5A, Small GTP-binding protein rab5

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
271457, 5868, 64633

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
M0RC99, P20339, Q9CQD1

Gene Symbols:
RAB5A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human RAB5A (NP_0041532)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA588262

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Antigen:
ISG15

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ISG15

Gene Alias:
G1P2, hUCRP, IFI15, IGI15, IMD38, interferon, alpha-inducible protein, interferon, alpha-inducible protein (clone IFI-15K), interferon-induced 15 kDa protein, interferon-induced 15-KDa protein, interferon-induced 17 kDa protein, interferon-induced 17-kDa/15-kDa protein, interferon-stimulated protein (15 kDa), interferon-stimulated protein 15, interferon-stimulated protein, 15 kDa, IP17, Irfp, Isg15, ISG15 ubiquitin like modifier, ISG15 ubiquitin-like modifier, ubiquitin cross-reactive protein, Ubiquitin-like protein ISG15, UCRP

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298693, 9636

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.74 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P05161

Gene Symbols:
ISG15

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human ISG15 (NP_0050921)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA588263

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Antigen:
PML

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PML

Gene Alias:
1200009E24Rik, AI661194, MYL, Pml, PML/RARA fusion, pml1, PP8675, probable transcription factor PML, promyelocytic leukemia, promyelocytic leukemia protein, promyelocytic leukemia, inducer of, protein PML, RGD1562602, RING finger protein 71, RNF71, TRIM19, tripartite motif protein TRIM19, tripartite motif-containing protein 19

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5371

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration:
2.42 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P29590

Gene Symbols:
PML

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human PML (NP_1502412)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG