PIPA585801
Phospho-STAT3 (Tyr705) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585801-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585801 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-STAT3 (Tyr705)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20848, 6774
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.66 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.
P40763, P42227
Gene Symbols
STAT3
Immunogen
Carrier-protein conjugated synthetic peptide corresponding to residues around human STAT3 (phospho Tyr705).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)
- Positive Control: hIFN-alpha treated HeLa whole cell extracts
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
Compare Similar Items
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Antigen: Phospho-STAT3 (Tyr705)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20848, 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.66 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P40763, P42227
Gene Symbols: STAT3
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human STAT3 (phospho Tyr705).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT3 (Tyr705)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.66 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P40763, P42227
Gene Symbols:
STAT3
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human STAT3 (phospho Tyr705).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PDGFRB (Tyr857)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pdgfrb
Gene Alias: AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18596, 5159
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.16 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: P05622, P09619
Gene Symbols: Pdgfrb
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human PDGF Receptor beta (phospho Tyr857).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PDGFRB (Tyr857)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pdgfrb
Gene Alias:
AI528809; Beta platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; CD140 antigen-like family member B; CD140B; CD140b antigen; IBGC4; IMF1; JTK12; KOGS; PDGF beta chain; PDGF Receptor beta; Pdgfr; Pdgfr1; PDGFR-1; PDGFRB; PDGF-R-beta; PDGFR-beta; PENTT; platelet derived growth factor receptor beta; platelet derived growth factor receptor, beta polypeptide; platelet-derived growth factor receptor 1; Platelet-derived growth factor receptor beta; platelet-derived growth factor receptor beta variant 1; Platelet-derived growth factor receptor, beta; platelet-derived growth factor receptor, beta polypeptide
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18596, 5159
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.16 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
P05622, P09619
Gene Symbols:
Pdgfrb
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human PDGF Receptor beta (phospho Tyr857).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-PDGFRB (Tyr771)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pdgfrb
Gene Alias: AI528809, Beta platelet-derived growth factor receptor, beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140B, CD140b antigen, IBGC4, IMF1, JTK12, KOGS, PDGF beta chain, PDGF Receptor beta, Pdgfr, Pdgfr1, PDGFR-1, PDGFRB, PDGF-R-beta, PDGFR-beta, PENTT, platelet derived growth factor receptor beta, platelet derived growth factor receptor, beta polypeptide, platelet-derived growth factor receptor 1, Platelet-derived growth factor receptor beta, platelet-derived growth factor receptor beta variant 1, Platelet-derived growth factor receptor, beta, platelet-derived growth factor receptor, beta polypeptide
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18596, 5159
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.66 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P05622, P09619
Gene Symbols: Pdgfrb
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human PDGF Receptor beta (phospho Tyr771).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-PDGFRB (Tyr771)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pdgfrb
Gene Alias:
AI528809, Beta platelet-derived growth factor receptor, beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, CD140B, CD140b antigen, IBGC4, IMF1, JTK12, KOGS, PDGF beta chain, PDGF Receptor beta, Pdgfr, Pdgfr1, PDGFR-1, PDGFRB, PDGF-R-beta, PDGFR-beta, PENTT, platelet derived growth factor receptor beta, platelet derived growth factor receptor, beta polypeptide, platelet-derived growth factor receptor 1, Platelet-derived growth factor receptor beta, platelet-derived growth factor receptor beta variant 1, Platelet-derived growth factor receptor, beta, platelet-derived growth factor receptor, beta polypeptide
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18596, 5159
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.66 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P05622, P09619
Gene Symbols:
Pdgfrb
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human PDGF Receptor beta (phospho Tyr771).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-FGFR1 (Tyr653, Tyr654)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FGFR1
Gene Alias: 2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; basic fibroblast growth factor receptor I; BFGFR; bFGF-R; bFGF-R-1; CD331; CD331 antigen; CEK; CEK1; cek1 protein; cek1 protein precursor; c-fgr; Eask; ECCL; FGF receptor; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFR1IIIC; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); fibroblast growth factor receptor 1-IIIc; fibroblast growth factor receptor type 1; Flg; FLT2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1; MFR; N-sam; OGD; proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14182, 2260, 79114
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.99 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: P11362, P16092, Q04589
Gene Symbols: FGFR1
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human FGFR1 (phospho Tyr653/654).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FGFR1 (Tyr653, Tyr654)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FGFR1
Gene Alias:
2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; basic fibroblast growth factor receptor I; BFGFR; bFGF-R; bFGF-R-1; CD331; CD331 antigen; CEK; CEK1; cek1 protein; cek1 protein precursor; c-fgr; Eask; ECCL; FGF receptor; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFR1IIIC; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); fibroblast growth factor receptor 1-IIIc; fibroblast growth factor receptor type 1; Flg; FLT2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1; MFR; N-sam; OGD; proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14182, 2260, 79114
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.99 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
P11362, P16092, Q04589
Gene Symbols:
FGFR1
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human FGFR1 (phospho Tyr653/654).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG