PIPA585445
Phospho-STAT3 (Tyr705) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585445-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585445 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-STAT3 (Tyr705)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STAT3
Gene Alias
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20848, 6774
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.
P40763, P42227
Gene Symbols
STAT3
Immunogen
Carrier-protein conjugated synthetic peptide corresponding to residues around human STAT3 (phospho Tyr705).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Bovine (100%)
- Positive Control: HeLa (starvation for 16 hr), HeLa ( starvation for 16 hr, and 100 ng/mL hIFN-alpha treatment for 5 min)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- STAT3 belongs to the family of STAT (signal transducers and activators of transcription) proteins which are phosphorylated by receptor associated kinases, translocate to the nucleus, and act as transcription factors in response to cytokines and growth factors
- Coactivators such as CREB-binding protein are required for the transcriptional activation by STAT3
- STAT3 can also be activated by Interferon-alpha, Interferon-gamma, EGF, PDGF and IL6
- Phosphorylation on tyrosine 705 by JAK1 and JAK2 is essential for STAT3 dimer formation, nuclear translocation, and DNA binding activity
- In humans, the STAT3 gene is located on the q arm of chromosome 17
- STAT3 has been shown to be activated by IFN-alpha but not IFN-beta
- The transcription factors associated with STAT3 are c-Jun and cyclic AMP-responsive enhancer binding protein (CREB)
- STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis
- The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3 while the PIAS3 protein is a specific inhibitor of STAT3
- Three alternatively spliced transcript variants encoding distinct isoforms of STAT3 have been described
- Deletion of the STAT3 gene in knock-out mice was lethal at the early embryonic stage.
Compare Similar Items
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Antigen: Phospho-STAT3 (Tyr705)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT3
Gene Alias: 1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20848, 6774
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P40763, P42227
Gene Symbols: STAT3
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human STAT3 (phospho Tyr705).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT3 (Tyr705)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT3
Gene Alias:
1110034C02Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, APRF, AW109958, DNA-binding protein APRF, FLJ20882, HIES, MGC16063, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), signal transducer, activator of transcription, acute-phase response factor, signal transduction and activation of transcription 3, STAT, STAT3, STAT-3, stat3 protein, STAT3b1, STAT3b2, transcription factor, Unknown (protein for MGC:128731), wu:fc15d02, wu:fl59g06, z-Stat3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20848, 6774
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P40763, P42227
Gene Symbols:
STAT3
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human STAT3 (phospho Tyr705).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: EXOSC5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EXOSC5
Gene Alias: Chronic myelogenous leukemia tumor antigen 28; CML28; D7Wsu180e; EXOSC5; Exosome complex component RRP46; exosome complex exonuclease RRP46; exosome complex exonuclease RRP46; exosome complex component RRP46; exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p; si:ch211-194n6.2; Unknown (protein for MGC:153707); zgc:153707
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56915
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.35 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q9NQT4
Gene Symbols: EXOSC5
Immunogen: Full length human EXOSC5 Recombinant protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
EXOSC5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EXOSC5
Gene Alias:
Chronic myelogenous leukemia tumor antigen 28; CML28; D7Wsu180e; EXOSC5; Exosome complex component RRP46; exosome complex exonuclease RRP46; exosome complex exonuclease RRP46; exosome complex component RRP46; exosome component 5; exosome component Rrp46; hRrp46p; p12B; Ribosomal RNA-processing protein 46; RRP41B; RRP46; Rrp46p; si:ch211-194n6.2; Unknown (protein for MGC:153707); zgc:153707
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56915
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.35 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q9NQT4
Gene Symbols:
EXOSC5
Immunogen:
Full length human EXOSC5 Recombinant protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Complement C3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: C3
Gene Alias: Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; I79_008227; LOC100060539; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 12266, 718
Content And Storage: 4° C
Form: Liquid
Applications: Immunohistochemistry (Frozen), Western Blot
Concentration: 0.1 mg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P01024, P01027
Gene Symbols: C3
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Complement C3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
C3
Gene Alias:
Acylation stimulating protein; acylation-stimulating protein cleavage product; AHUS5; AI255234; ARMD9; ASP; C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3a; C3a anaphylatoxin; C3adesArg; C3b; C3bc; C3-beta-c; C3d; complement C3; Complement C3 alpha chain; Complement C3 beta chain; complement C3 protein (GPC3) precursor; Complement C3b alpha' chain; Complement C3c alpha' chain fragment 1; Complement C3c alpha' chain fragment 2; Complement C3d fragment; Complement C3dg fragment; Complement C3f fragment; Complement C3g fragment; complement component 3; complement component C3; complement component C3 alpha-chain; complement component C3a; complement component C3b; complement component C3d; CPAMD1; ENCF-1; ENCF-2; epididymis secretory sperm binding protein Li 62p; HEL-S-62p; HSE-MSF; I79_008227; LOC100060539; Neutrophil chemotactic factor-1; Neutrophil chemotactic factor-2; Plp; prepro-C3; Unknown (protein for MGC:134562)
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
12266, 718
Content And Storage:
4° C
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Western Blot
Concentration:
0.1 mg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P01024, P01027
Gene Symbols:
C3
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: beta Tubulin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tubb3
Gene Alias: 2310057H16Rik, 2810484G07Rik, 3200002H15Rik, AA408537, AI325297, AI596182, B130022C14Rik, bA631M21.2, BB220206, beta 5-tubulin, beta Ib tubulin, beta tubulin, beta tubulin 1, beta-4, beta-4 tubulin, beta-4-tubulin, beta-5, beta-5 tubulin, beta5-tubulin, betaIII-tubulin, beta-tubulin, beta-tubulin class-III, Beta-tubulin class-V, beta-tubulin class-VI, Beta-tubulin isotype I, c(beta)7 tubulin, CDCBM, CDCBM1, CDCBM5, CDCBM6, CFEOM3, CFEOM3A, class I beta tubulin, Class I beta-tubulin, class IIa beta-tubulin, class III beta-tubulin, class IVa beta-tubulin, class V beta tubulin, class V beta-tubulin, CSCSC1, dJ40E16.7, dystonia 4, torsion (autosomal dominant), DYT4, FEOM3, HSA10p15 beta-tubulin 4Q, HsT1601, hypothetical protein LOC540236, hypothetical protein LOC550458, I79_000194, I79_012097, LOC100349792, LOC100761889, LOW QUALITY PROTEIN: tubulin beta-6 chain, M(beta)1, M(beta)2, M(beta)3, M(beta)4, M(beta)5, M(beta)6, M40, M40 antibody, MGC128415 protein, MGC137802 protein, neuron-specific class III beta-tubulin, OK/SW-cl.56, OOMD, OOMD2, RGD1305887, si:ch211-122i22.4, si:ch211-9a18.2, Tubb, tubb beta-5, tubb.L, Tubb1, TUBB2, Tubb2a, tubb2a {ECO:0000250, Tubb3, TUBB4, TUBB4A, tubb5, TUBB-5, TUBB6, TUBB8, Tubulin 5 beta, tubulin beta, tubulin beta 1 class VI, tubulin beta 2A class IIa, tubulin beta 3 class III, tubulin beta 4', tubulin beta 4A class IVa, tubulin beta 6 class V, tubulin beta 8 class VIII, Tubulin beta chain, tubulin beta class I, tubulin beta class I L homeolog, Tubulin beta class IIa, Tubulin beta class V, tubulin beta MGC4083, tubulin beta-1, tubulin beta-1 chain, tubulin beta-1 chain-like, tubulin beta-2A chain, tubulin beta-2B chain, tubulin beta-3 chain, Tubulin beta-4 chain, tubulin beta-4A chain, Tubulin beta-5 chain, tubulin beta-5 chain, tubulin beta-6 chain, tubulin beta-6 chain, Tubulin beta-7 chain, tubulin beta-8 chain, Tubulin beta-III, tubulin, beta 1 class VI, tubulin, beta 2, tubulin, beta 2A, tubulin, beta 2A class IIA, tubulin, beta 3, tubulin, beta 3 class III, tubulin, beta 4, tubulin, beta 4 class IVa, tubulin, beta 4A class IVa, tubulin, beta 5, tubulin, beta 5 class I, tubulin, beta 6 class V, tubulin, beta class I, tubulin, beta family 1, tubulin, beta polypeptide, tubulin, beta polypeptide 2, tubulin, beta, 3, tubulin, beta, 4, tubulin, beta, 5, uncharacterized protein LOC550458, UniProtKB:Q7TMM9}, Unknown (protein for MGC:134115), unnamed protein product, XELAEV_18039222mg, XLOT, zbetaI, zgc:112515
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10381, 10382, 203068, 347688, 7280, 81027, 84617
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.68 mg/mL
Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: P04350, P07437, Q13509, Q13885, Q3ZCM7, Q9BUF5, Q9H4B7
Gene Symbols: TUBB, Tubb1, Tubb2a, Tubb3, Tubb4a, Tubb6, TUBB8
Immunogen: Recombinant protein encompassing a sequence within the center region of human beta Tubulin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
beta Tubulin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tubb3
Gene Alias:
2310057H16Rik, 2810484G07Rik, 3200002H15Rik, AA408537, AI325297, AI596182, B130022C14Rik, bA631M21.2, BB220206, beta 5-tubulin, beta Ib tubulin, beta tubulin, beta tubulin 1, beta-4, beta-4 tubulin, beta-4-tubulin, beta-5, beta-5 tubulin, beta5-tubulin, betaIII-tubulin, beta-tubulin, beta-tubulin class-III, Beta-tubulin class-V, beta-tubulin class-VI, Beta-tubulin isotype I, c(beta)7 tubulin, CDCBM, CDCBM1, CDCBM5, CDCBM6, CFEOM3, CFEOM3A, class I beta tubulin, Class I beta-tubulin, class IIa beta-tubulin, class III beta-tubulin, class IVa beta-tubulin, class V beta tubulin, class V beta-tubulin, CSCSC1, dJ40E16.7, dystonia 4, torsion (autosomal dominant), DYT4, FEOM3, HSA10p15 beta-tubulin 4Q, HsT1601, hypothetical protein LOC540236, hypothetical protein LOC550458, I79_000194, I79_012097, LOC100349792, LOC100761889, LOW QUALITY PROTEIN: tubulin beta-6 chain, M(beta)1, M(beta)2, M(beta)3, M(beta)4, M(beta)5, M(beta)6, M40, M40 antibody, MGC128415 protein, MGC137802 protein, neuron-specific class III beta-tubulin, OK/SW-cl.56, OOMD, OOMD2, RGD1305887, si:ch211-122i22.4, si:ch211-9a18.2, Tubb, tubb beta-5, tubb.L, Tubb1, TUBB2, Tubb2a, tubb2a {ECO:0000250, Tubb3, TUBB4, TUBB4A, tubb5, TUBB-5, TUBB6, TUBB8, Tubulin 5 beta, tubulin beta, tubulin beta 1 class VI, tubulin beta 2A class IIa, tubulin beta 3 class III, tubulin beta 4', tubulin beta 4A class IVa, tubulin beta 6 class V, tubulin beta 8 class VIII, Tubulin beta chain, tubulin beta class I, tubulin beta class I L homeolog, Tubulin beta class IIa, Tubulin beta class V, tubulin beta MGC4083, tubulin beta-1, tubulin beta-1 chain, tubulin beta-1 chain-like, tubulin beta-2A chain, tubulin beta-2B chain, tubulin beta-3 chain, Tubulin beta-4 chain, tubulin beta-4A chain, Tubulin beta-5 chain, tubulin beta-5 chain, tubulin beta-6 chain, tubulin beta-6 chain, Tubulin beta-7 chain, tubulin beta-8 chain, Tubulin beta-III, tubulin, beta 1 class VI, tubulin, beta 2, tubulin, beta 2A, tubulin, beta 2A class IIA, tubulin, beta 3, tubulin, beta 3 class III, tubulin, beta 4, tubulin, beta 4 class IVa, tubulin, beta 4A class IVa, tubulin, beta 5, tubulin, beta 5 class I, tubulin, beta 6 class V, tubulin, beta class I, tubulin, beta family 1, tubulin, beta polypeptide, tubulin, beta polypeptide 2, tubulin, beta, 3, tubulin, beta, 4, tubulin, beta, 5, uncharacterized protein LOC550458, UniProtKB:Q7TMM9}, Unknown (protein for MGC:134115), unnamed protein product, XELAEV_18039222mg, XLOT, zbetaI, zgc:112515
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10381, 10382, 203068, 347688, 7280, 81027, 84617
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.68 mg/mL
Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
P04350, P07437, Q13509, Q13885, Q3ZCM7, Q9BUF5, Q9H4B7
Gene Symbols:
TUBB, Tubb1, Tubb2a, Tubb3, Tubb4a, Tubb6, TUBB8
Immunogen:
Recombinant protein encompassing a sequence within the center region of human beta Tubulin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG