PIPA587693

TPMT Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587693-Each-of-1 In Stock ₹ 44,705.10

PIPA587693 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TPMT

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TPMT

Gene Alias

AW106912, HGNC:12014, S-adenosyl-L-methionine:thiopurine S-methyltransferase, thiopurine methyltransferase, Thiopurine S-methyltransferase, TPMT, TPMTD, truncated thiopurine methyltransferase

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

7172

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1.37 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P51580

Gene Symbols

TPMT

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPMT (NP_0003581)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MDGTRTSLDI EEYSDTEVQK NQVLTLEEWQ DKWVNGKTAF HQEQGHQLLK KHLDTFLKGK SGLRVFFPLC GKAVEMKWFA DRGHSVVGVE ISELGIQEFF TEQNLSYSEE PITEIPGTKV FKSSSGNISL YCCSIFDLPR TNIGKFDMIW DRGALVAINP GDRKCYADTM FSLLGKKFQY LLCVLSYDPT KHPGPPFYVP HAEIERLFGK ICNIRCLEKV DAFEERHKSW GIDCLFEKLY LLTEK; Positive Samples: K562; Cellular Location: Cytoplasm Catalyzes the S-methylation of thiopurine drugs such as 6-mercaptopurine
  • Defects in TPMT are the cause of thiopurine S-methyltransferase deficiency (TPMT deficiency)
  • TPMT is an enzyme involved in the normal metabolic inactivation of thiopurine drugs
  • These drugs are generally used as immunosupressants or cytotoxic drugs and are prescribed for a variety of clinical conditions including leukemia, autoimmune disease and organ transplantation
  • Patients with intermediate or no TPMT activity are at risk of toxicity after receiving standard doses of thiopurine drugs and it is shown that inter-individual differences in response to these drugs are largely determined by genetic variation at the TPMT locus.

Compare Similar Items

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Img

Thermo Scientific

PIPA587693

--


Antigen:
TPMT

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TPMT

Gene Alias:
AW106912, HGNC:12014, S-adenosyl-L-methionine:thiopurine S-methyltransferase, thiopurine methyltransferase, Thiopurine S-methyltransferase, TPMT, TPMTD, truncated thiopurine methyltransferase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7172

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P51580

Gene Symbols:
TPMT

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-245 of human TPMT (NP_0003581)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587695

--


Antigen:
PDX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDX1

Gene Alias:
DLDBP, E3BP, Glucose-sensitive factor, GSF, Idx1, IDX-1, Insulin promoter factor 1, insulin promoter factor 1, homeodomain transcription factor, insulin promotor factor 1, insulin upstream factor 1, Ipf1, IPF-1, Islet/duodenum homeobox 1, islet/duodenum homeobox-1, IUF1, IUF-1, MODY4, PAGEN1, Pancreas/duodenum homeobox protein 1, pancreatic and duodenal homeobox 1, pancreatic and duodenal homeobox gene 1, pancreatic-duodenal homeobox factor 1, PDHX, PDX1, pdx-1, somatostatin transactivating factor 1, somatostatin transcription factor 1, somatostatin-transactivating factor 1, Stf1, STF-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18609, 3651

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.62 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P52945, P52946

Gene Symbols:
PDX1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PDX1 (NP_0002001)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587696

--


Antigen:
CNPase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CNP

Gene Alias:
2', 3' cyclic nucleotide 3' phosphohydrolase, 2',3'-cyclic nucleotide 3' phosphodiesterase, 2',3'-cyclic nucleotide 3' phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, 2',3'-cyclic-nucleotide 3'-phosphodiesterase, CNP, Cnp1, Cnp-1, CNPase, CNPF, CNPI, CNPII, cyclic nucleotide phosphodiesterase 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1267, 12799, 25275

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.84 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P09543, P13233, P16330

Gene Symbols:
CNP

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-421 of human CNPase (NP_1491243)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587699

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Antigen:
ADAM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adam2

Gene Alias:
a disintegrin and metallopeptidase domain 2, a disintegrin and metalloprotease domain 2, a disintegrin and metalloprotease domain (ADAM) 2, a disintegrin and metalloprotease domain 2 (fertilin beta), a disintegrin and metalloproteinase, ADAM, ADAM 2, ADAM metallopeptidase domain 2, Adam2, ADAMs, AI323749, cancer/testis antigen 15, CRYN1, CRYN2, CT15, Disintegrin and metalloproteinase domain-containing protein 2, fertilin beta, fertilin subunit beta, FTNB, metalloendopeptidases, PH30, PH-30, PH-30b, Ph30-beta

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11495, 2515, 56806

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q60718, Q63202, Q99965

Gene Symbols:
Adam2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 476-686 of human ADAM2 (Q99965)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG