PIPA587901

Thymidylate Synthase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587901-Each-of-1 In Stock ₹ 44,705.10

PIPA587901 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Thymidylate Synthase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TYMS

Gene Alias

HST422, MGC88736, OK/SW-cl.29, Thymidylate synthase, thymidylate synthetase, TMS, TS, Tsase, Tyms, tysy

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22171, 7298

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

2.12 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P04818, P07607

Gene Symbols

TYMS

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human TYMS (NP_0010621)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MPVAGSELPR RPLPPAAQER DAEPRPPHGE LQYLGQIQHI LRCGVRKDDR TGTGTLSVFG MQARYSLRDE FPLLTTKRVF WKGVLEELLW FIKGSTNAKE LSSKGVKIWD ANGSRDFLDS LGFSTREEGD LGPVYGFQWR HFGAEYRDME SDYSGQGVDQ LQRVIDTIKT NPDDRRIIMC AWNPRDLPLM ALPPCHALCQ FYVVNSELSC QLYQRSGDMG LGVPFNIASY ALLTYMIAHI TGLKPGDFIH TLGDAHIYLN HIEPLKIQLQ REPRPFPKLR ILRKVEKIDD FKAEDFQIEG YNPHPTIKME MAV; Positive Samples: A-431, Jurkat, DU145, Mouse kidney, Mouse spleen; Cellular Location: Cytoplasm, Mitochondrion, Mitochondrion inner membrane, Mitochondrion matrix, Nucleus Thymidylate Synthase (TS) converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis
  • TS is a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors
  • Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate
  • Expression of TS protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.

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Thermo Scientific

PIPA587901

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Antigen:
Thymidylate Synthase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TYMS

Gene Alias:
HST422, MGC88736, OK/SW-cl.29, Thymidylate synthase, thymidylate synthetase, TMS, TS, Tsase, Tyms, tysy

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22171, 7298

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.12 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P04818, P07607

Gene Symbols:
TYMS

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-313 of human TYMS (NP_0010621)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587902

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Antigen:
beta Synuclein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNCB

Gene Alias:
AI838531, betaSYN, beta-synuclein, Phosphoneuroprotein 14, PNP 14, Sncb, synuclein beta, synuclein, beta

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
104069, 113893

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.01 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q63754, Q91ZZ3

Gene Symbols:
SNCB

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-134 of human beta-Synuclein (NP_0010015021)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587912

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Antigen:
HMHA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ARHGAP45

Gene Alias:
6330406L22Rik, ARHGAP45, AW539505, Ha-1, histocompatibility (minor) HA-1, HLA-HA1, Hmha1, KIAA0223, mHag HA-1, Minor histocompatibility antigen HA-1, minor histocompatibility protein HA-1, minor histocompatibility protein HA-1, rho GTPase-activating protein 45, RGD1308662, Rho GTPase activating protein 45, rho GTPase-activating protein 45

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23526, 314618

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q92619

Gene Symbols:
ARHGAP45

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ARHGAP45 (NP_0364242)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587914

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Antigen:
NFKBIL1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFKBIL1

Gene Alias:
DADB-70P7.2, Def-7, ikappaBL, I-kappa-B-like protein, Ikbl, Inhibitor of kappa B-like protein, LST1, NF-kappa-B inhibitor-like protein 1, NFKB inhibitor like 1, NFKBIL, NFKBIL1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4795

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.06 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q9UBC1

Gene Symbols:
NFKBIL1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human NFKBIL1 (NP_0049983)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG