PIPA587912
HMHA1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587912-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587912 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
HMHA1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARHGAP45
Gene Alias
6330406L22Rik, ARHGAP45, AW539505, Ha-1, histocompatibility (minor) HA-1, HLA-HA1, Hmha1, KIAA0223, mHag HA-1, Minor histocompatibility antigen HA-1, minor histocompatibility protein HA-1, minor histocompatibility protein HA-1, rho GTPase-activating protein 45, RGD1308662, Rho GTPase activating protein 45, rho GTPase-activating protein 45
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
23526, 314618
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
3 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q92619
Gene Symbols
ARHGAP45
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ARHGAP45 (NP_0364242)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MFSRKKRELM KTPSISKKNR AGSPSPQPSG ELPRKDGADA VFPGPSLEPP AGSSGVKATG TLKRPTSLSR HASAAGFPLS GAASWTLGRS HRSPLTAASP GELPTEGAGP DVVEDISHLL ADVARFAEGL EKLKECVLRD DLLEARRPRA HECLGEALRV; Positive Samples: U-251MG, LO2, DU145 Contains a GTPase activator for the Rho-type GTPases (RhoGAP) domain that would be able to negatively regulate the actin cytoskeleton as well as cell spreading
- However, also contains N-terminally a BAR-domain which is able to play an autoinhibitory effect on this RhoGAP activity
- Precursor of the histocompatibility antigen HA-1
- More generally, minor histocompatibility antigens (mHags) refer to immunogenic peptide which, when complexed with MHC, can generate an immune response after recognition by specific T-cells
- The peptides are derived from polymorphic intracellular proteins, which are cleaved by normal pathways of antigen processing
- The binding of these peptides to MHC class I or class II molecules and its expression on the cell surface can stimulate T-cell responses and thereby trigger graft rejection or graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation from HLA-identical sibling donor
- GVHD is a frequent complication after bone marrow transplantation (BMT), due to mismatch of minor histocompatibility antigen in HLA-matched sibling marrow transplants
- Specifically, mismatching for mHag HA-1 which is recognized as immunodominant, is shown to be associated with the development of severe GVHD after HLA-identical BMT
- HA-1 is presented to the cell surface by MHC class I HLA-A*0201, but also by other HLA-A alleles
- This complex specifically elicits donor-cytotoxic T-lymphocyte (CTL) reactivity against hematologic malignancies after treatment by HLA-identical allogenic BMT
- It induces cell recognition and lysis by CTL.
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Antigen: HMHA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARHGAP45
Gene Alias: 6330406L22Rik, ARHGAP45, AW539505, Ha-1, histocompatibility (minor) HA-1, HLA-HA1, Hmha1, KIAA0223, mHag HA-1, Minor histocompatibility antigen HA-1, minor histocompatibility protein HA-1, minor histocompatibility protein HA-1, rho GTPase-activating protein 45, RGD1308662, Rho GTPase activating protein 45, rho GTPase-activating protein 45
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23526, 314618
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q92619
Gene Symbols: ARHGAP45
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ARHGAP45 (NP_0364242)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
HMHA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARHGAP45
Gene Alias:
6330406L22Rik, ARHGAP45, AW539505, Ha-1, histocompatibility (minor) HA-1, HLA-HA1, Hmha1, KIAA0223, mHag HA-1, Minor histocompatibility antigen HA-1, minor histocompatibility protein HA-1, minor histocompatibility protein HA-1, rho GTPase-activating protein 45, RGD1308662, Rho GTPase activating protein 45, rho GTPase-activating protein 45
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23526, 314618
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q92619
Gene Symbols:
ARHGAP45
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human ARHGAP45 (NP_0364242)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NFKBIL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NFKBIL1
Gene Alias: DADB-70P7.2, Def-7, ikappaBL, I-kappa-B-like protein, Ikbl, Inhibitor of kappa B-like protein, LST1, NF-kappa-B inhibitor-like protein 1, NFKB inhibitor like 1, NFKBIL, NFKBIL1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4795
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.06 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9UBC1
Gene Symbols: NFKBIL1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human NFKBIL1 (NP_0049983)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NFKBIL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NFKBIL1
Gene Alias:
DADB-70P7.2, Def-7, ikappaBL, I-kappa-B-like protein, Ikbl, Inhibitor of kappa B-like protein, LST1, NF-kappa-B inhibitor-like protein 1, NFKB inhibitor like 1, NFKBIL, NFKBIL1, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor like 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4795
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.06 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9UBC1
Gene Symbols:
NFKBIL1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-381 of human NFKBIL1 (NP_0049983)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PDE1A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDE1A
Gene Alias: 3'-RACE clone 8 phosphodiesterase 1A, 3-RACE clone 8 phosphodiesterase 1A, 3'-RACEclone8phosphodiesterase1A, 3-RACEclone8phosphodiesterase1A, 61 kDa Cam-PDE, AI987702, AW125737, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase, cam-PDE 1A, CAM-PDE-1A, HCAM1, hCam-1, HS MGC26303, HSPDE1A, MGC26303, Pde1a, phosphodiesterase 1A, phosphodiesterase 1A, calmodulin-dependent, phosphodiesterase-1A
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18573, 5136, 81529
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.68 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P54750, Q61481
Gene Symbols: PDE1A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_0050102)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PDE1A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDE1A
Gene Alias:
3'-RACE clone 8 phosphodiesterase 1A, 3-RACE clone 8 phosphodiesterase 1A, 3'-RACEclone8phosphodiesterase1A, 3-RACEclone8phosphodiesterase1A, 61 kDa Cam-PDE, AI987702, AW125737, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A, calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase, cam-PDE 1A, CAM-PDE-1A, HCAM1, hCam-1, HS MGC26303, HSPDE1A, MGC26303, Pde1a, phosphodiesterase 1A, phosphodiesterase 1A, calmodulin-dependent, phosphodiesterase-1A
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18573, 5136, 81529
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.68 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P54750, Q61481
Gene Symbols:
PDE1A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 446-545 of human PDE1A (NP_0050102)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PEX6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pex6
Gene Alias: AI132582, D130055I09Rik, HMLR2, mKIAA4177, PAF 2, Paf2, Paf-2, PBD4A, PDB4B, Peroxin 6, Peroxin-6, peroxisomal AAA-type ATPase 1, peroxisomal biogenesis factor 6, Peroxisomal-type ATPase 1, peroxisome assembly factor 2, peroxisome biogenesis factor 6, PEX6, PXAAA1, RP1-125M3.3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 224824, 5190
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 4.23 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q13608, Q99LC9
Gene Symbols: Pex6
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 741-980 of human PEX6 (NP_0002783)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PEX6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pex6
Gene Alias:
AI132582, D130055I09Rik, HMLR2, mKIAA4177, PAF 2, Paf2, Paf-2, PBD4A, PDB4B, Peroxin 6, Peroxin-6, peroxisomal AAA-type ATPase 1, peroxisomal biogenesis factor 6, Peroxisomal-type ATPase 1, peroxisome assembly factor 2, peroxisome biogenesis factor 6, PEX6, PXAAA1, RP1-125M3.3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
224824, 5190
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
4.23 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q13608, Q99LC9
Gene Symbols:
Pex6
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 741-980 of human PEX6 (NP_0002783)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG