PIPA587968

RAP1GAP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587968-Each-of-1 In Stock ₹ 44,705.10

PIPA587968 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

RAP1GAP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RAP1GAP

Gene Alias

1300019I11Rik, 2310004O14Rik, AI427470, ARPP-90, KIAA0474, RAP1 GTPase activating protein, Rap1 GTPase-activating protein, rap1 GTPase-activating protein 1, Rap1, GTPase-activating protein 1, Rap1ga1, Rap1GAP, Rap1GAP1, RAP1GAPII, RAPGAP

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5909

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

1.56 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P47736

Gene Symbols

RAP1GAP

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 508-727 of human Rap1GAP (NP_0011391301)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: AMGLSNKKPN TVSTSHSGSF APNNPDLAKA AGISLIVPGK SPTRKKSGPF GSRRSSAIGI ENIQEVQEKR ESPPAGQKTP DSGHVSQEPK SENSSTQSSP EMPTTKNRAE TAAQRAEALK DFSRSSSSAS SFASVVEETE GVDGEDTGLE SVSSSGTPHK RDSFIYSTWL EDSVSTTSGG SSPGPSRSPH PDAGKLGDPA CPEIKIQLEA SEQHMPQLGC; Positive Samples: U-87MG, 293T, SGC-7901, LO2; Cellular Location: Golgi apparatus membrane, Peripheral membrane protein Rap1GAP specifically stimulates GTP hydrolytic activity of the monomeric G protein Rap1
  • Physical interaction between G alpha z, a member of the Gi family of trimeric G proteins, and Rap1GAP blocks the ability of regulators of G protein signaling to stimulate GTP hydrolysis of the alpha subunit, and also attenuates the ability of activated G alpha z to inhibit adenylyl cyclase
  • Rap1GAP is expressed in the brain, kidney and pancreas and may act as a signal integrator to coordinate and/or integrate Gz signaling and Rap1 signaling in cells
  • A novel isoform of Rapl GTPase-activating protein, designated Rap1GAPII, binds specifically to G alpha z
  • Stimulation of the Gi-coupled M2 Muscarinic receptor translocates Rap1GAPII from the cytosol to the membrane and decreases the amount of GTP-bound Rap1, resulting in the activation of ERK/MAPK.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA587968

--


Antigen:
RAP1GAP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAP1GAP

Gene Alias:
1300019I11Rik, 2310004O14Rik, AI427470, ARPP-90, KIAA0474, RAP1 GTPase activating protein, Rap1 GTPase-activating protein, rap1 GTPase-activating protein 1, Rap1, GTPase-activating protein 1, Rap1ga1, Rap1GAP, Rap1GAP1, RAP1GAPII, RAPGAP

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5909

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.56 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P47736

Gene Symbols:
RAP1GAP

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 508-727 of human Rap1GAP (NP_0011391301)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587971

--


Antigen:
TCEA1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TCEA1

Gene Alias:
GTF2S, SII, S-II, TCEA, Tcea1, Tceat, TF2S, TFIIS, transcription elongation factor A (SII) 1, transcription elongation factor A (SII), 1, transcription elongation factor A protein 1, Transcription elongation factor A protein 1-like protein, transcription elongation factor A1, transcription elongation factor S-II protein 1, Transcription elongation factor TFIIS.o, transcription factor IIS

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6917

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P23193

Gene Symbols:
TCEA1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 75-140 of human TCEA1 (NP_0067471)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA587973

--


Antigen:
VDAC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VDAC3

Gene Alias:
channel protein VDAC3, HD-VDAC3, mitochondrial outer membrane protein, mitochondrial voltage dependent anion channel 3, mVDAC3, outer mitochondrial membrane protein porin 3, rVDAC3, Vdac3, VDAC-3, voltage dependent anion channel 3, voltage-dependent anion channel 3, voltage-dependent anion-selective channel protein 3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22335, 7419

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.63 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
Q60931, Q9Y277

Gene Symbols:
VDAC3

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-283 of human VDAC3 (NP_0056533)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587974

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Antigen:
LGR5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Lgr5

Gene Alias:
Fex, follicle expressed hormone, G protein-coupled receptor 49, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, GRP49, HG38, leucine rich repeat containing G protein coupled receptor 5, leucine rich repeat containing G protein-coupled receptor 5, leucine-rich repeat containing G protein-coupled receptor 5, leucine-rich repeat-containing G protein-coupled receptor 5, leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5, orphan G protein-coupled receptor HG38, orphan G-protein coupled receptor FEX

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14160, 299802, 8549

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.92 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
D4AC13, O75473, Q9Z1P4

Gene Symbols:
Lgr5

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5/GPR49 (NP_003658.1).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG