PIPA588090
POLR2A Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588090-Each-of-1 | In Stock | ₹ 46,074.06 |
PIPA588090 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,074.06
GST (18%): ₹ 8,293.331
Total Price: ₹ 54,367.391
Antigen
POLR2A
Classification
Polyclonal
Conjugate
Unconjugated
Gene
POLR2A
Gene Alias
220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
20020, 363633, 5430
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1.83 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
P08775, P24928
Gene Symbols
POLR2A
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-260 of human POLR2A (NP_0009281)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: HeLa, BT-474, H460, Jurkat, Mouse testis, Mouse brain; Cellular Location: Nucleus Immunogen sequence: MHGGGPPSGD SACPLRTIKR VQFGVLSPDE LKRMSVTEGG IKYPETTEGG RPKLGGLMDP RQGVIERTGR CQTCAGNMTE CPGHFGHIEL AKPVFHVGFL VKTMKVLRCV CFFCSKLLVD SNNPKIKDIL AKSKGQPKKR LTHVYDLCKG KNICEGGEEM DNKFGVEQPE GDEDLTKEKG HGGCGRYQPR IRRSGLELYA EWKHVNEDSQ EKKILLSPER VHEIFKRISD EECFVLGMEP RYARPEWMIV TVLPVPPLSV DNA-directed RNA polymerase II subunit RPB1 (POLR1A) is a DNA-dependent RNA polymerase that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
- POLR1A is the largest subunit and is a catalytic component of RNA polymerase II which synthesizes mRNA precurors and many functional non-coding RNAs
- It also forms the polymerase active center together with the second largest subunit
- Pol II is the central component of the basal RNA polymerase II transcription machinery
- It is composed of mobile elements that move relative to each other
- RPB1 is part of the core element with the central large cleft, the clamp element that moves to open and close the cleft, and the jaws that are though to grab the incoming DNA template
- At the start of transcription, a single-stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol II
- A bridging helix emanates from RPB1 and crosses the cleft near the catalytic stie and is through to promote translocation of Pol II by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition
- During transcription elongation, Pol II moves on the template as the transcript elongates
- Elongation is influenced by the phosphorylation status of the C-terminal domain (CTD) of Pol II's largest subunit (RPB1), which serves as a platform for assembly of factors that regulate transcription initiation, elongation, termination, and mRNA processing
- Regulation of gene expression levels depends on the balance between methylation and acetylation levelts of the CTD-lysines.
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Antigen: POLR2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLR2A
Gene Alias: 220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20020, 363633, 5430
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.83 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P08775, P24928
Gene Symbols: POLR2A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-260 of human POLR2A (NP_0009281)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
POLR2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLR2A
Gene Alias:
220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20020, 363633, 5430
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.83 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P08775, P24928
Gene Symbols:
POLR2A
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-260 of human POLR2A (NP_0009281)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Glucagon
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gcg
Gene Alias: GCG, Glicentin, Glicentin-related polypeptide, GLP1, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP1/2, GLP2, GLP-2, Glu, glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, glucagon-like peptide-1, GRPP, IL12p35, IL12P40, Incretin hormone, OXM, OXY, Oxyntomodulin, porcine proglucagon, PPG, preproglucagon, proglucagon
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14526, 24952, 2641
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 0.58 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P01275, P06883, P55095
Gene Symbols: Gcg
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_0020451)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Glucagon
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gcg
Gene Alias:
GCG, Glicentin, Glicentin-related polypeptide, GLP1, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP1/2, GLP2, GLP-2, Glu, glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, glucagon-like peptide-1, GRPP, IL12p35, IL12P40, Incretin hormone, OXM, OXY, Oxyntomodulin, porcine proglucagon, PPG, preproglucagon, proglucagon
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14526, 24952, 2641
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
0.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P01275, P06883, P55095
Gene Symbols:
Gcg
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_0020451)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FAK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTK2
Gene Alias: CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14083, 25614, 5747
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O35346, P34152, Q05397
Gene Symbols: PTK2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_7225601)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FAK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTK2
Gene Alias:
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14083, 25614, 5747
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O35346, P34152, Q05397
Gene Symbols:
PTK2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_7225601)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Transthyretin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TTR
Gene Alias: AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22139, 24856, 7276
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.72 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P02766, P02767, P07309
Gene Symbols: TTR
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_0003621)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Transthyretin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TTR
Gene Alias:
AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22139, 24856, 7276
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.72 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P02766, P02767, P07309
Gene Symbols:
TTR
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_0003621)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG