PIPA588093
FAK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588093-Each-of-1 | In Stock | ₹ 46,330.74 |
PIPA588093 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,330.74
GST (18%): ₹ 8,339.533
Total Price: ₹ 54,670.273
Antigen
FAK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTK2
Gene Alias
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14083, 25614, 5747
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
O35346, P34152, Q05397
Gene Symbols
PTK2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_7225601)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: QHMVQTNHYQ VSGYPGSHGI TAMAGSIYPG QASLLDQTDS WNHRPQEIAM WQPNVEDSTV LDLRGIGQVL PTHLMEERLI RQQQEMEEDQ RWLEKEERFL K Positive Samples: Jurkat, U-87MG, HeLa; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, cell cortex, centrosome, cytoskeleton, focal adhesion, microtubule organizing center Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
- FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
- FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
- Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
- Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
- In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
- In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
- Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.
Compare Similar Items
Show Difference
Antigen: FAK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTK2
Gene Alias: CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14083, 25614, 5747
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O35346, P34152, Q05397
Gene Symbols: PTK2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_7225601)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
FAK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTK2
Gene Alias:
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14083, 25614, 5747
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O35346, P34152, Q05397
Gene Symbols:
PTK2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 734-834 of human FAK (NP_7225601)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Transthyretin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TTR
Gene Alias: AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22139, 24856, 7276
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.72 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P02766, P02767, P07309
Gene Symbols: TTR
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_0003621)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Transthyretin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TTR
Gene Alias:
AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22139, 24856, 7276
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.72 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P02766, P02767, P07309
Gene Symbols:
TTR
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_0003621)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MSH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Msh2
Gene Alias: AI788990, COCA1, DNA mismatch repair protein MSH2, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, mismatch repair ATPase MSH2, mismatch repair protein, MSH2, Msh2p, mutS homolog 2, mutS homolog 2 (E. coli), mutS homolog 2, colon cancer, nonpolyposis type 1, mutS protein homolog 2, O0935, PMS5, YOL090W
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81709
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.11 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P54275
Gene Symbols: Msh2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_0002421)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Rat, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MSH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Msh2
Gene Alias:
AI788990, COCA1, DNA mismatch repair protein MSH2, FCC1, hMSH2, HNPCC, HNPCC1, LCFS2, mismatch repair ATPase MSH2, mismatch repair protein, MSH2, Msh2p, mutS homolog 2, mutS homolog 2 (E. coli), mutS homolog 2, colon cancer, nonpolyposis type 1, mutS protein homolog 2, O0935, PMS5, YOL090W
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81709
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.11 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P54275
Gene Symbols:
Msh2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_0002421)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Rat, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TGFBI
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TGFBI
Gene Alias: 68kDa, AI181842, AI747162, beta ig-h3, Beta-ig, beta-ig-h3, betaig-h3, BIGH3, Big-h3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, kerato-epithelin, LCD1, MP70, MP78, RGD-CAP, RGD-containing collagen-associated protein, TGFBI, transforming growth factor beta induced, transforming growth factor beta-induced 68kDa, transforming growth factor induced protein, transforming growth factor, beta induced, transforming growth factor, beta induced, 68 kDa, transforming growth factor, beta-induced, 68kD, transforming growth factor, beta-induced, 68kDa, Transforming growth factor-beta-induced protein ig-h3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 21810, 7045
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.66 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P82198, Q15582
Gene Symbols: TGFBI
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_0003491)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TGFBI
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TGFBI
Gene Alias:
68kDa, AI181842, AI747162, beta ig-h3, Beta-ig, beta-ig-h3, betaig-h3, BIGH3, Big-h3, CDB1, CDG2, CDGG1, CSD, CSD1, CSD2, CSD3, EBMD, kerato-epithelin, LCD1, MP70, MP78, RGD-CAP, RGD-containing collagen-associated protein, TGFBI, transforming growth factor beta induced, transforming growth factor beta-induced 68kDa, transforming growth factor induced protein, transforming growth factor, beta induced, transforming growth factor, beta induced, 68 kDa, transforming growth factor, beta-induced, 68kD, transforming growth factor, beta-induced, 68kDa, Transforming growth factor-beta-induced protein ig-h3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
21810, 7045
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.66 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P82198, Q15582
Gene Symbols:
TGFBI
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TGF beta induced (TGFBI) (NP_0003491)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG