PIPA588578

SHP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588578-Each-of-1 In Stock ₹ 47,614.14

PIPA588578 - Each of 1

₹ 47,614.14

In Stock

Quantity

1

Base Price: ₹ 47,614.14

GST (18%): ₹ 8,570.545

Total Price: ₹ 56,184.685

Antigen

SHP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTPN11

Gene Alias

2700084A17Rik, AW536184, bptp3, CFC, cSH-PTP2, encodes catalytic domain, HCP, HGNC:9644, JMML, METCDS, MGC14433, Noonan syndrome 1, ns1, null, OTTHUMP00000166108, phosphotyrosyl-protein phosphatase, protein tyrosine phosphatase non-receptor type 11, protein tyrosine phosphatase SH-PTP2, protein tyrosine phosphatase, non-receptor type 11, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), protein tyrosine phosphatase, non-receptor type 11 S homeolog, protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, protein-tyrosine phosphatase SYP, PTP1C, PTP1D, PTP-1D, ptp-2, PTP2C, PTP-2C, Ptpn11, ptpn11.S, ptpn11-a, ptpn11-b, SAP-2, SH2 domain-containing protein tyrosine phosphatase-2, Shp2, shp-2, SHPTP2, SH-PTP2, SH-PTP2 protein tyrosine phosphatase non-receptor type 11, SH-PTP2 protein tyrosine phosphatase, non-receptor type 11, SH-PTP3, Syp, Tyrosine-protein phosphatase non-receptor type 11, XELAEV_18010676mg

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19247, 25622, 5781

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration

1.66 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P35235, P41499, Q06124

Gene Symbols

PTPN11

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-460 of human SHP2 (NP_0028253)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA588442

--

Img

Thermo Scientific

PIPA587692

--

Img

Thermo Scientific

PIPA587643

--

Img

Thermo Scientific

PIPA587602

--

Img

Thermo Scientific

PIPA585429

--

Img

Thermo Scientific

PIPA588421

--

Img

Thermo Scientific

PIPA588677

--

Img

Thermo Scientific

PIPA588140

--

Description

  • Immunogen sequence: MTSRRWFHPN ITGVEAENLL LTRGVDGSFL ARPSKSNPGD FTLSVRRNGA VTHIKIQNTG DYYDLYGGEK FATLAELVQY YMEHHGQLKE KNGDVIELKY PLNCADPTSE RWFHGHLSGK EAEKLLTEKG KHGSFLVRES QSHPGDFVLS VRTGDDKGES NDGKSKVTHV MIRCQELKYD VGGGERFDSL TDLVEHYKKN PMVETLGTVL QLKQPLNTTR INAAEIESRV RELSKLAETT DKVKQGFWEE FETLQQQECK LLYSRKEGQR QENKNKNRYK NILPFDHTRV VLHDGDPNEP VSDYINANII MPEFETKCNN SKPKKSYIAT QGCLQNTVND FWRMVFQENS RVIVMTTKEV ERGKSKCVKY WPDEYALKEY GVMRVRNVKE SAAHDYTLRE LKLSKVGQGN TERTVWQYHF RTWPDHGVPS DPGGVLDFLE EVHHKQESIM DAGPVVVHCS; Positive Samples: U-87MG, Jurkat, A-431, MCF-7, Mouse brain, Rat brain, Rat lung; Cellular Location: Cytoplasm The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family
  • PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation
  • This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates
  • This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration
  • Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA588578

--


Antigen:
SHP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTPN11

Gene Alias:
2700084A17Rik, AW536184, bptp3, CFC, cSH-PTP2, encodes catalytic domain, HCP, HGNC:9644, JMML, METCDS, MGC14433, Noonan syndrome 1, ns1, null, OTTHUMP00000166108, phosphotyrosyl-protein phosphatase, protein tyrosine phosphatase non-receptor type 11, protein tyrosine phosphatase SH-PTP2, protein tyrosine phosphatase, non-receptor type 11, protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), protein tyrosine phosphatase, non-receptor type 11 S homeolog, protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, protein-tyrosine phosphatase SYP, PTP1C, PTP1D, PTP-1D, ptp-2, PTP2C, PTP-2C, Ptpn11, ptpn11.S, ptpn11-a, ptpn11-b, SAP-2, SH2 domain-containing protein tyrosine phosphatase-2, Shp2, shp-2, SHPTP2, SH-PTP2, SH-PTP2 protein tyrosine phosphatase non-receptor type 11, SH-PTP2 protein tyrosine phosphatase, non-receptor type 11, SH-PTP3, Syp, Tyrosine-protein phosphatase non-receptor type 11, XELAEV_18010676mg

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19247, 25622, 5781

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Concentration:
1.66 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P35235, P41499, Q06124

Gene Symbols:
PTPN11

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-460 of human SHP2 (NP_0028253)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588579

--


Antigen:
RAD51C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAD51C

Gene Alias:
BROVCA3, DNA repair protein RAD51 homolog 3, FANCO, MGC104277, R51H3, RAD51 homolog C, RAD51 paralog C, RAD51C, RAD51L2, RAD51-like protein 2, RGD1563765, yeast RAD51 homolog 3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5889

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry

Concentration:
0.23 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O43502

Gene Symbols:
RAD51C

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-135 of human RAD51C (NP_0028671)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588580

--


Antigen:
RAG2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAG2

Gene Alias:
RAG 2, Rag2, RAG-2, recombinase activating gene 2, recombination activating gene 2, recombination activating protein 2, V(D)J recombination-activating protein 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19374, 5897

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.7 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P21784, P55895

Gene Symbols:
RAG2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 258-527 of human RAG2 (NP_0012307151)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588581

--


Antigen:
SHMT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Shmt1

Gene Alias:
AI324848, AI385541, C81125, CSHMT, cytoplasmic serine hydroxymethyltransferase, cytosolic form, cytosolic serine hydroxymethyltransferase, glycine hydroxymethyltransferase, LRRGT00032, MEL-32, MGC15229, MGC24556, mshmt, mshmt1, mshmt2, serine hydroxymethyl transferase, serine hydroxymethyltransferase, serine hydroxymethyltransferase 1, serine hydroxymethyltransferase 1 (soluble), serine hydroxymethyltransferase 1 (soluble) isoform 1, serine hydroxymethyltransferase 2 (mitochondrial), serine hydroxymethyltransferase, cytosolic, Serine methylase, SHMT, Shmt1, shmt1 protein, SHMT2, zgc:66171, zgc:77524, zSHMT-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20425, 287379, 6470

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.84 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P34896, P50431

Gene Symbols:
Shmt1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 285-444 of human SHMT1 (NP_6837181)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG