PIPA588144
SMAD2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588144-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588144 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SMAD2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SMAD2
Gene Alias
7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17126, 29357, 4087
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration
1.68 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O70436, Q15796, Q62432
Gene Symbols
SMAD2
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (NP_0058921)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: mouse lung, mouse kidney; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE LEKAITTQNC NTKCVTIPST CSEIWGLSTP NTIDQWDTTG SMAD2 (MADH2, MAD2) regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation
- SMAD2 interacts with the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation into the nucleus is a central event in TGF beta signaling
- Phosphorylation of threonine 8 in the calmodulin-binding region of the MH1 domain by extracellular signal regulated kinase 1 (ERK1) enhances SMAD2 transcriptional activity, which is negatively regulated by calmodulin
- In response to the TGF-beta signal, SMAD2 is phosphorylated by the TGF-beta receptors
- The phosphorylation induces the dissociation of this protein with SARA and the association with the family member SMAD4
- The association with SMAD4 is important for the translocation of this protein into the nucleus, where it binds to target promoters and forms a transcription repressor complex with other cofactors
- SMAD2 can also be phosphorylated by activin type 1 receptor kinase, and mediates the signal from the activin
- Alternatively spliced transcript variants encoding the SMAD2 protein have been observed.
Compare Similar Items
Show Difference
Antigen: SMAD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SMAD2
Gene Alias: 7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17126, 29357, 4087
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 1.68 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O70436, Q15796, Q62432
Gene Symbols: SMAD2
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (NP_0058921)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SMAD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SMAD2
Gene Alias:
7120426M23Rik, EGK_09664, hMAD-2, hSMAD2, JV18, JV18-1, MAD, MAD homolog 2, Mad protein homolog, Madh2, Madr2, Mad-related protein 2, MGC22139, MGC34440, mMad2, mother against DPP homolog 2, mothers against decapentaplegic homolog 2, Mothers against decapentaplegic-like protein 2, mothers against DPP homolog 2, pSMAD2, Sma- and Mad-related protein 2, SMAD, SMAD 2, SMAD family member 2, SMAD, mothers against DPP homolog 2, Smad2, Smad-2, Smad2Deltaexon3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17126, 29357, 4087
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
1.68 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
O70436, Q15796, Q62432
Gene Symbols:
SMAD2
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Smad2 (NP_0058921)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RRM1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RRM1
Gene Alias: cb396, cb838, CHUNP6866, hypothetical protein, R RRM 1, r1, RI RI RR 1, Ribonucleoside-diphosphate reductase large subunit, ribonucleoside-diphosphate reductase M1 chain, ribonucleoside-diphosphate reductase subunit M1, ribonucleotide reductase catalytic subunit M1, ribonucleotide reductase large subunit, ribonucleotide reductase M1, ribonucleotide reductase M1 L homeolog, ribonucleotide reductase M1 polypeptide, ribonucleotide reductase M1 S homeolog, ribonucleotide reductase protein R1 class I, ribonucleotide reductase subunit M1, ribonucleotide reductase, R1 subunit, RIR 1, RIR1, RnrM1, RR1, Rrm1, rrm1 protein, rrm1.L, rrm1.S, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XELAEV_18013932mg, XRRM1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20133, 6240, 685579
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P07742, P23921
Gene Symbols: RRM1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_0010241)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RRM1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RRM1
Gene Alias:
cb396, cb838, CHUNP6866, hypothetical protein, R RRM 1, r1, RI RI RR 1, Ribonucleoside-diphosphate reductase large subunit, ribonucleoside-diphosphate reductase M1 chain, ribonucleoside-diphosphate reductase subunit M1, ribonucleotide reductase catalytic subunit M1, ribonucleotide reductase large subunit, ribonucleotide reductase M1, ribonucleotide reductase M1 L homeolog, ribonucleotide reductase M1 polypeptide, ribonucleotide reductase M1 S homeolog, ribonucleotide reductase protein R1 class I, ribonucleotide reductase subunit M1, ribonucleotide reductase, R1 subunit, RIR 1, RIR1, RnrM1, RR1, Rrm1, rrm1 protein, rrm1.L, rrm1.S, sb:cb548, wu:fb39b07, wu:fi14b02, wu:fk95f07, XELAEV_18013932mg, XRRM1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20133, 6240, 685579
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P07742, P23921
Gene Symbols:
RRM1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 593-792 of human RRM1 (NP_0010241)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: BRCA1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRCA1
Gene Alias: brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 672
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.34 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P38398
Gene Symbols: BRCA1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 901-1000 of human BRCA1 (NP_0092251)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
BRCA1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRCA1
Gene Alias:
brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
672
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.34 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P38398
Gene Symbols:
BRCA1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 901-1000 of human BRCA1 (NP_0092251)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TRIF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TICAM1
Gene Alias: AW046014, AW547018, hCG_39321, HSD34, IIAE6, MyD88-3, Proline-rich, vinculin and TIR domain-containing protein B, PRVTIRB, Putative NF-kappa-B-activating protein 502H, RNF36, TI, Ticam1, TICAM-1, TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter molecule 1, TIR domain-containing adapter protein inducing IFN-beta, TIR domain-containing adaptor inducing interferon-beta, TIR-domain containing adaptor inducing interferon-beta, toll like receptor adaptor molecule 1, toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta, toll-interleukin I receptor domain containing adaptor molecule 1, toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, toll-like receptor adaptor molecule 1, TRIF
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 106759, 148022, 363328
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2.58 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q80UF7, Q8IUC6
Gene Symbols: TICAM1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-280 of human TRIF / TICAM1 (NP_8915491)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TRIF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TICAM1
Gene Alias:
AW046014, AW547018, hCG_39321, HSD34, IIAE6, MyD88-3, Proline-rich, vinculin and TIR domain-containing protein B, PRVTIRB, Putative NF-kappa-B-activating protein 502H, RNF36, TI, Ticam1, TICAM-1, TIR domain containing adaptor inducing interferon-beta, TIR domain-containing adapter molecule 1, TIR domain-containing adapter protein inducing IFN-beta, TIR domain-containing adaptor inducing interferon-beta, TIR-domain containing adaptor inducing interferon-beta, toll like receptor adaptor molecule 1, toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta, toll-interleukin I receptor domain containing adaptor molecule 1, toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta, toll-like receptor adaptor molecule 1, TRIF
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
106759, 148022, 363328
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q80UF7, Q8IUC6
Gene Symbols:
TICAM1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-280 of human TRIF / TICAM1 (NP_8915491)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG