PIPA588293

TrkB Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588293-Each-of-1 In Stock ₹ 44,705.10

PIPA588293 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TrkB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ntrk2

Gene Alias

AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25054, 4915

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.18 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q16620, Q63604

Gene Symbols

Ntrk2

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 41-433 of human TrkB (NP_0010070981)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SRIWCSDPSP GIVAFPRLEP NSVDPENITE IFIANQKRLE IINEDDVEAY VGLRNLTIVD SGLKFVAHKA FLKNSNLQHI NFTRNKLTSL SRKHFRHLDL SELILVGNPF TCSCDIMWIK TLQEAKSSPD TQDLYCLNES SKNIPLANLQ IPNCGLPSAN LAAPNLTVEE GKSITLSCSV AGDPVPNMYW DVGNLVSKHM NETSHTQGSL RITNISSDDS GKQISCVAEN LVGEDQDSVN LTVHFAPTIT FLESPTSDHH WCIPFTVKGN PKPALQWFYN GAILNESKYI CTKIHVTNHT EYHGCLQLDN PTHMNNGDYT LIAKNEYGKD EKQISAHFMG WPGIDDGANP NYPDVIYEDY GTAANDIGDT TNRSNEIPST DVTDKTGREH LSV; Positive Samples: K-562, Rat brain; Cellular Location: Cell membrane, Endosome membrane, Single-pass type I membrane protein NTRK2 (TRKB) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system
  • NTRK2 is the receptor for brain-derived neurotrophic factor (BDNF)
  • Together, NTRK2 and BDNF regulate both short-term synaptic functions and long-term potentiation of brain synapses
  • TrkB is involved in the development and maintenance of the nervous system
  • Moreover, Trk B is a tyrosine kinase gene highly related to Trk A
  • Trk B expression is confined to tissues within the central and peripheral nervous systems
  • The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by Trk B, although BDNF elicits a response at least two orders of magnitude greater than NT-3
  • TrkB is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway
  • Signaling through TrkB leads to cell differentiation
  • Mutations in the TrkB gene have been associated with obesity and mood disorders
  • Alternate transcriptional splice variants encoding different isoforms have been found for the TrkB gene.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA588293

--


Antigen:
TrkB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ntrk2

Gene Alias:
AI848316, BDNF/NT-3 growth factors receptor, BDNF-tropomyosine receptor kinase B, C030027L06Rik, EC 2.7.10.1, GP145 TrkB, GP145TrkB, GP145-TrkB, GP145-TrkB/GP95-TrkB, GP95 TrkB, GP95-TrkB, hyperphagia, kinase TrkB, neural receptor protein-tyrosine kinase (trkB), neurotrophic receptor tyrosine kinase 2, neurotrophic tyrosine kinase receptor type 2, neurotrophic tyrosine kinase, receptor, type 2, neurotrophic tyrosine receptor kinase type 2, NTRK 2, Ntrk2, OTTHUMP00000021573, OTTHUMP00000021574, OTTHUMP00000021576, OTTHUMP00000021577, RATTRKB1, Tkrb, Trk B, TRKB, trk-B, trkB protein, trkB tyrosine kinase, TRKB1, Tropomyosin-related kinase B, tyrosine kinase receptor B

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25054, 4915

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q16620, Q63604

Gene Symbols:
Ntrk2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-433 of human TrkB (NP_0010070981)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588295

--


Antigen:
ZSCAN4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZSCAN4

Gene Alias:
BQ559217, C330039H09Rik, RGD1563625, zinc finger and SCAN domain containing 4, zinc finger and SCAN domain containing 4A, zinc finger and SCAN domain containing 4F, zinc finger and SCAN domain containing protein 4F, Zinc finger and SCAN domain-containing protein 4, zinc finger protein 494, ZNF494, ZSCAN4, Zscan4a, Zscan4f

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
201516

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8NAM6

Gene Symbols:
ZSCAN4

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-227 of human ZSCAN4 (NP_6898901)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588296

--


Antigen:
ZSCAN4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Zscan4f

Gene Alias:
BQ559217, C330039H09Rik, RGD1563625, zinc finger and SCAN domain containing 4, zinc finger and SCAN domain containing 4A, zinc finger and SCAN domain containing 4F, zinc finger and SCAN domain containing protein 4F, Zinc finger and SCAN domain-containing protein 4, zinc finger protein 494, ZNF494, ZSCAN4, Zscan4a, Zscan4f

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
503124

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.47 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
__

Gene Symbols:
Zscan4f

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-310 of human ZSCAN4 (NP_6898901)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588298

--


Antigen:
TAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05, C87327, hypothetical protein LOC553788, I79_000697, M3K7, map3k7, map3k7.L, MAPKKK, MEKK7, mitogen activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7 L homeolog, RP1-154G14.1, si:ch211-225h9.1, Tak1, TAK1z, TGF1a, TGF-beta activated kinase 1, TGF-beta-activated kinase 1, TGF-beta-activated kinase TAK1, transforming growth factor beta-activated kinase 1, transforming growth factor-beta-activated kinase 1, XELAEV_18027270mg, xTAK1, zgc:110612

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26409, 313121, 6885

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
O43318, P0C8E4, Q62073

Gene Symbols:
MAP3K7

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-325 of human TAK1 (NP_6633041)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG