PIPA588456

CIP2A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA588456-Each-of-1 In Stock ₹ 44,277.30

PIPA588456 - Each of 1

₹ 44,277.30

In Stock

Quantity

1

Base Price: ₹ 44,277.30

GST (18%): ₹ 7,969.914

Total Price: ₹ 52,247.214

Antigen

CIP2A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cip2a

Gene Alias

AA408511, AU018569, C330027C09Rik, Cancerous inhibitor of PP2A, cancerous inhibitor of protein phosphatase 2A, Cip2a, Kiaa1524, p90, p90 autoantigen, p90 autoantigen homolog, Protein CIP2A, RGD1310335, RIKEN cDNA C330027C09 gene, similar to RIKEN cDNA C330027C09

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

224171, 360711, 57650

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.27 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

Q8BWY9, Q8TCG1

Gene Symbols

Cip2a

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 681-905 of human KIAA1524 (NP_0659412)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: EVERKNEELS VLLKAQQVES ERAQSDIEHL FQHNRKLESV AEEHEILTKS YMELLQRNES TEKKNKDLQI TCDSLNKQIE TVKKLNESLK EQNEKSIAQL IEKEEQRKEV QNQLVDREHK LANLHQKTKV QEEKIKTLQK EREDKEETID ILRKELSRTE QIRKELSIKA SSLEVQKAQL EGRLEEKESL VKLQQEELNK HSHMIAMIHS LSGGKINPET VNLSI; Positive Samples: HepG2, U-87MG, MCF7, HeLa, A375, Rat testis; Cellular Location: Cytoplasm, Membrane, Single-pass membrane protein Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells
  • The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation
  • In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation
  • The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A
  • Importantly, CIP2A is overexpressed in two common human malignancies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA588456

--


Antigen:
CIP2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cip2a

Gene Alias:
AA408511, AU018569, C330027C09Rik, Cancerous inhibitor of PP2A, cancerous inhibitor of protein phosphatase 2A, Cip2a, Kiaa1524, p90, p90 autoantigen, p90 autoantigen homolog, Protein CIP2A, RGD1310335, RIKEN cDNA C330027C09 gene, similar to RIKEN cDNA C330027C09

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
224171, 360711, 57650

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q8BWY9, Q8TCG1

Gene Symbols:
Cip2a

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 681-905 of human KIAA1524 (NP_0659412)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588458

--


Antigen:
AP2S1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP2S1

Gene Alias:
adapter-related protein complex 2 sigma subunit, adapter-related protein complex 2 subunit sigma, adaptor protein complex AP-2 subunit sigma, adaptor related protein complex 2 sigma 1 subunit, adaptor-related protein complex 2 sigma 1 subunit, adaptor-related protein complex 2 subunit sigma, adaptor-related protein complex 2, sigma 1 subunit, AI043088, Ap17, AP17-DELTA, AP-2 complex subunit sigma, AP2S1, Claps2, Clathrin assembly protein 2 sigma small chain, clathrin assembly protein 2 small chain, clathrin coat assembly protein AP17, Clathrin coat-associated protein AP17, clathrin-associated protein 17, clathrin-associated/assembly/adaptor protein, small 2 (17kD), FBH3, FBHOk, HA2 17 kDa subunit, HHC3, Plasma membrane adaptor AP-2 17 kDa protein, Sigma2-adaptin, sigma-adaptin 3b

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1175, 232910, 65046

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.02 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P53680, P62743, P62744

Gene Symbols:
AP2S1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human AP2S1 (NP_0040602)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588460

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Antigen:
PPIH

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPIH

Gene Alias:
1100001J08Rik, 2010111B15Rik, 4833408F11Rik, AI464484, cyclophilin H, CYP20, CYP-20, CYPH, D4Wsu43e, peptidyl prolyl isomerase H, peptidyl-prolyl cis-trans isomerase H, peptidylprolyl isomerase H, peptidylprolyl isomerase H (cyclophilin H), PPIase h, Ppih, RGD1564921, Rotamase H, small nuclear ribonucleoprotein particle-specific cyclophilin H, SnuCyp-20, USA-CYP, USA-CyP SnuCyp-20, U-snRNP-associated cyclophilin SnuCyp-20, U-snRNP-associated cyclophilin SunCyp-20

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10465, 366461

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
4.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O43447

Gene Symbols:
PPIH

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-177 of human PPIH (NP_0063381)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA588461

--


Antigen:
TSNAX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSNAX

Gene Alias:
R74833, translin associated factor X, translin-associated factor X, Translin-associated protein X, translin-like protein, Trax, TSNAX

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
53424, 7257

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q99598, Q9QZE7

Gene Symbols:
TSNAX

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TSNAX (NP_0059901)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG