PIPA589569

IFI16 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA589569-Each-of-1 In Stock ₹ 44,705.10

PIPA589569 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IFI16

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFI16

Gene Alias

gamma-interferon-inducible protein 16, IFI 16C, IFI16, Ifi-16, IFNGIP1, interferon gamma inducible protein 16, interferon, gamma-inducible protein 16, interferon-gamma induced protein IFI 16, interferon-inducible myeloid differentiation transcriptional activator, PYHIN2

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3428

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.46 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q16666

Gene Symbols

IFI16

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IFI16 (NP_0013517961)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Immunogen sequence: MGKKYKNIVL LKGLEVINDY HFRMVKSLLS NDLKLNLKMR EEYDKIQIAD LMEEKFRGDA GLGKLIKIFE DIPTLEDLAE TLKKEKLKVK GPALSRKRKK EVDATSPAPS TSSTVKTEGA EATPGAQKRK KSTKEKAGPK GSKVSEEQTQ PPSPAGAGMS TAMGRSPSPK TSLSAPPNSS STENPKTVAK CQVTPRRNVL QKRPVIVKVL STTKPFEYET PEMEKKIMFH ATVATQTQFF HVKVLNTSLK EKFNGKKIII ISDYLEYDSL LEVNEESTVS EAGPNQTFEV PNKIINRAKE; Positive Samples: Mouse spleen, Mouse lung; Cellular Location: Cytoplasm, Nucleus IFI16 (gamma-inteferon-inducible protein 16) binds double-stranded DNA
  • It binds preferentially to supercoiled DNA and cruciform DNA structures
  • It seems to be involved in transcriptional regulation and as a transcriptional repressor
  • IFI16 may have a role in the regulation of hematopoietic differentiation through activation of unknown target genes
  • It controls cellular proliferation by modulating the functions of cell cycle regulatory factors including p53/TP53 and the retinoblastoma protein
  • IFI16 is also involved in innate immune response by recognizing viral dsDNA in the cytosol and nucleus
  • After binding to viral DNA in the cytoplasm, IFI16 recruits TMEM173/STING and mediates the induction of IFN-beta
  • It is necessary to activate the IFR3 signaling cascade suring human herpes simplex virus 1 infection and promotes the assembly of heterochromatin on herpesviral DNA and inhibiton of viral immediate-early gene expression and replication
  • IFI16 is also involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

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Img

Thermo Scientific

PIPA589569

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Antigen:
IFI16

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFI16

Gene Alias:
gamma-interferon-inducible protein 16, IFI 16C, IFI16, Ifi-16, IFNGIP1, interferon gamma inducible protein 16, interferon, gamma-inducible protein 16, interferon-gamma induced protein IFI 16, interferon-inducible myeloid differentiation transcriptional activator, PYHIN2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3428

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.46 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q16666

Gene Symbols:
IFI16

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human IFI16 (NP_0013517961)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589571

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Antigen:
IFIT3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFIT3

Gene Alias:
cig41, CIG49, CIG-49, Garg49, GARG-49, Glucocorticoid-attenuated response gene 49 protein, Ifi49, IFI60, IFI-60K, IFIT3, IFIT-3, IFIT4, IFIT-4, interferon induced protein with tetratricopeptide repeats 3, interferon-induced 60 kDa protein, Interferon-induced protein with tetratricopeptide repeats 3, interferon-induced protein with tetratricopeptide repeats 4, interferon-stimulated protein 60, IRG2, Isg49, ISG60, ISG-60, P49, P60, retinoic acid-induced gene G protein, RIG-G, RP11-149I23.4

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
15959, 309526, 3437

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O14879, Q64345

Gene Symbols:
IFIT3

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of mouse IFIT3 (NP_0346311)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589572

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Antigen:
IGF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGF2

Gene Alias:
AL033362, C11orf43, FLJ22066, FLJ44734, GRDF, H-IGF-2, IGF, Igf2, Igf-2, IGFII, Igf-II, Insulin like growth factor, insulin like growth factor 2, insulin-like growth factor 2, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor II (IGF-II), Insulin-like growth factor II (somatomedin A), Insulin-like growth factor II Ala-25 Del, insulin-like growth factor II isoform 2 variant 4 preprotein, insulin-like growth factor type 2, M6pr, Mpr, MSA, multiplication-stimulating activity, Multiplication-stimulating polypeptide, Peg2, PP1446, PP9974, preptin, RNIGF2, Somatomedin-A, T3M-11-derived growth factor

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16002, 24483, 3481

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
3.54 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P01344, P01346, P09535

Gene Symbols:
IGF2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 26-127 of human IGF2 (NP_0006031)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA589574

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Antigen:
FIBB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Fgb

Gene Alias:
2510049G14Rik, Ab1-181, Ab1-216, Ac1-581, B beta polypeptide, beta-fibrinogen, epididymis secretory sperm binding protein Li 78p, Fgb, fibrinogen, Fibrinogen beta chain, fibrinogen, B beta polypeptide, fibrinogen, beta polypeptide, Fibrinopeptide B, HEL-S-78p, Liver regeneration-related protein LRRG036/LRRG043/LRRG189, MGC104327, MGC120405

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110135, 2244, 24366

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P02675, P14480, Q8K0E8

Gene Symbols:
Fgb

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 111-222 of human FGB (NP_0051322)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG