PIPA589598
PTS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA589598-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA589598 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
PTS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pts
Gene Alias
6-pyruvoyl tetrahydrobiopterin synthase, 6-pyruvoyltetrahydropterin synthase, 6-pyruvoyl-tetrahydropterin synthase, PTP synthase, PTPS, PTS
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
19286, 29498, 5805
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.93 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P27213, Q03393, Q9R1Z7
Gene Symbols
Pts
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_0003081)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: MSTEGGGRRC QAQVSRRISF SASHRLYSKF LSDEENLKLF GKCNNPNGHG HNYKVVVTVH GEIDPATGMV MNLADLKKYM EEAIMQPLDH KNLDMDVPYF ADVVSTTENV AVYIWDNLQK VLPVGVLYKV KVYETDNNIV VYKGE; Positive Samples: HeLa, U-251MG, Mouse kidney The tetrahydrobiopterin (BH4) cofactor is essential for hepatic hydroxylase, which is involved in phenylalanine degradation and catecholamine and serotonin biosynthesis
- BH4 is also an essential and limiting cofactor for all types of nitric oxide synthase
- BH4 deficiency results in hyperphenylalaninemia and monoamine neurotransmitter depletion and is most commonly due to autosomal recessive mutation in 6-pyruvoyltetrahydropterin synthase (PTPS), the second enzyme for BH4 biosynthesis
- The active site of PTPS consists of the pterin-anchoring Glu A107 neighbored by two catalytic motifs: a Zn(II) binding site and an inter-subunit catalytic triad formed by Cys A42, Asp B88 and His B89
- The active site of PTPS undergoes a Zn and Mg-dependent reaction that includes a triphosphate elimination, a stereospecific reduction and the oxidation of both side hydroxyl groups
- The catalytic triad of PTPS is involved in the deprotonation of the side-chain carbons of substrates
- In addition, Ser 19 of human PTPS may be a substrate for cGMP-dependent protein kinase type II phosphorylation in vivo, which is essential for normal activity of PTPS.
Compare Similar Items
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Antigen: PTS
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pts
Gene Alias: 6-pyruvoyl tetrahydrobiopterin synthase, 6-pyruvoyltetrahydropterin synthase, 6-pyruvoyl-tetrahydropterin synthase, PTP synthase, PTPS, PTS
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19286, 29498, 5805
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.93 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P27213, Q03393, Q9R1Z7
Gene Symbols: Pts
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_0003081)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTS
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pts
Gene Alias:
6-pyruvoyl tetrahydrobiopterin synthase, 6-pyruvoyltetrahydropterin synthase, 6-pyruvoyl-tetrahydropterin synthase, PTP synthase, PTPS, PTS
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19286, 29498, 5805
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.93 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P27213, Q03393, Q9R1Z7
Gene Symbols:
Pts
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human PTS (NP_0003081)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RPA14
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rpa3
Gene Alias: 14kDa, C330026P08Rik, REPA3, Replication factor A protein 3, replication protein A 14 kDa subunit, replication protein A3, replication protein A3, 14kDa, RF-A protein 3, RP-A p14, RPA14, RPA3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 296883, 6119, 68240
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2.14 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P35244, Q9CQ71
Gene Symbols: Rpa3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 6-121 of human RPA3 (NP_0029381)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RPA14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rpa3
Gene Alias:
14kDa, C330026P08Rik, REPA3, Replication factor A protein 3, replication protein A 14 kDa subunit, replication protein A3, replication protein A3, 14kDa, RF-A protein 3, RP-A p14, RPA14, RPA3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
296883, 6119, 68240
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2.14 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P35244, Q9CQ71
Gene Symbols:
Rpa3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 6-121 of human RPA3 (NP_0029381)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PTPN22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ptpn22
Gene Alias: 70zpep, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, lymphoid-specific protein tyrosine phosphatase, LyP, LYP1, LYP2, PEP, PEST domain-enriched tyrosine phosphatase, PEST-domain phosphatase, protein tyrosine phosphatase, non-receptor type 22, protein tyrosine phosphatase, non-receptor type 22 (lymphoid), protein tyrosine phosphatase, non-receptor type 8, Ptpn22, PTPN8, tyrosine-phosphatase, Tyrosine-protein phosphatase non-receptor type 22
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19260, 26191, 295338
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.15 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P29352, Q9Y2R2
Gene Symbols: Ptpn22
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_0365434)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PTPN22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ptpn22
Gene Alias:
70zpep, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, lymphoid-specific protein tyrosine phosphatase, LyP, LYP1, LYP2, PEP, PEST domain-enriched tyrosine phosphatase, PEST-domain phosphatase, protein tyrosine phosphatase, non-receptor type 22, protein tyrosine phosphatase, non-receptor type 22 (lymphoid), protein tyrosine phosphatase, non-receptor type 8, Ptpn22, PTPN8, tyrosine-phosphatase, Tyrosine-protein phosphatase non-receptor type 22
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19260, 26191, 295338
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.15 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P29352, Q9Y2R2
Gene Symbols:
Ptpn22
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PTPN22 (NP_0365434)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZNF195
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZNF195
Gene Alias: HRF1, hypoxia-regulated factor-1, krueppel family zinc finger protein (znfp104), zinc finger protein 195, ZNF195, ZNFP104
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7748
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.14 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O14628
Gene Symbols: ZNF195
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ZNF195 (NP_0011239911)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ZNF195
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZNF195
Gene Alias:
HRF1, hypoxia-regulated factor-1, krueppel family zinc finger protein (znfp104), zinc finger protein 195, ZNF195, ZNFP104
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7748
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.14 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O14628
Gene Symbols:
ZNF195
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ZNF195 (NP_0011239911)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG