PIPA590025

PAI1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA590025-Each-of-1 In Stock ₹ 44,705.10

PIPA590025 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PAI1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Serpine1

Gene Alias

Endothelial plasminogen activator inhibitor, nexin, plasminogen activator inhibitor type 1, PAI, PAI1, PAI-1, PAI1 protein, PAI1A, Pai1aa, Planh, Planh1, plas, plasminogen activator inhibitor, plasminogen activator inhibitor 1, plasminogen activator inhibitor I, plasminogen activator inhibitor, type I, plasminogen activator inhibitor-1, Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI), putative plasminogen activator inhibitor-1, RATPAI1A, serine (or cysteine) peptidase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, serine (or cysteine) proteinase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, member 1, serpin E1, serpin family E member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, SERPINE1, SERPINE-1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5054

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry

Concentration

0.75 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P05121

Gene Symbols

Serpine1

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 24-158 of human PAI-1/Serpin E1 (NP_0005931)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: VHHPPSYVAH LASDFGVRVF QQVAQASKDR NVVFSPYGVA SVLAMLQLTT GGETQQQIQA AMGFKIDDKG MAPALRHLYK ELMGPWNKDE ISTTDAIFVQ RDLKLVQGFM PHFFRLFRST VKQVDFSEVE RARFI PAI1 (plasminogen activator inhibitor 1) belongs to serine protease inhibitor superfamily, and is the principal inhibitor of tissue-type and urokinase-type plasminogen activators (tPA and uPA)
  • Platelets are the main source of the circulating PAI11, but it is synthesized and secreted by many tissue and cell types, including fibroblasts, smooth muscle cells, endothelial cells, hepatocytes, and inflammatory cells
  • Expression of PAI11 can be regulated at the transcriptional level by many factors including growth factors, cytokines, hormones, inflammatory factors, glucose or lipid metabolites, vascular tone regulating factors, chemicals, and other environmental or physical factors
  • PAI1 is present at increased levels in various disease states, and has been linked to an increased occurrence of thrombosis in obesity, thrombophilia and the metabolic syndrome
  • Defects in PAI-1 are characterized by abnormal bleeding
  • PAI1 mediates inhibition of fibrinolysis by inhibiting the activity of plasminogen activator, and may promote neuronal survival
  • Other defects in PAI1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency)
  • Alternatively spliced transcript variants encoding different isoforms of PAI1 have been found.

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Thermo Scientific

PIPA590025

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Antigen:
PAI1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Serpine1

Gene Alias:
Endothelial plasminogen activator inhibitor, nexin, plasminogen activator inhibitor type 1, PAI, PAI1, PAI-1, PAI1 protein, PAI1A, Pai1aa, Planh, Planh1, plas, plasminogen activator inhibitor, plasminogen activator inhibitor 1, plasminogen activator inhibitor I, plasminogen activator inhibitor, type I, plasminogen activator inhibitor-1, Plasminogen activator inhibitor-1 precursor (PAI-1) (Endothelial plasminogen activator inhibitor) (PAI), putative plasminogen activator inhibitor-1, RATPAI1A, serine (or cysteine) peptidase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, serine (or cysteine) proteinase inhibitor, clade E, member 1, serine (or cysteine) proteinase inhibitor, member 1, serpin E1, serpin family E member 1, serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1, SERPINE1, SERPINE-1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5054

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry

Concentration:
0.75 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P05121

Gene Symbols:
Serpine1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 24-158 of human PAI-1/Serpin E1 (NP_0005931)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA590029

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Antigen:
P-Glycoprotein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ABCB1

Gene Alias:
ABC superfamily, P-glycoprotein, ABC20, ABCB1, Abcb1a, Abcb1b, Abcb4, ATP binding cassette subfamily B member 1, ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1), ATP-binding cassette sub-family B member 1, ATP-binding cassette sub-family B member 1A, ATP-binding cassette sub-family B member 1B, ATP-binding cassette transporter subfamily B, member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1), ATP-binding cassette, subfamily B (MDR/TAP), member 1A, ATP-binding cassette, sub-family B (MDR/TAP), member 1A, ATP-binding cassette, subfamily B (MDR/TAP), member 1B, ATP-binding cassette, sub-family B (MDR/TAP), member 1B, ATP-binding cassette, sub-family B (MDR/TAP), member 4, ATP-binding cassette, subfamily B, member 1A, ATP-binding cassette, subfamily B, member 1B, ATP-dependent translocase ABCB1, ATP-dependent translocase ABCB1, multidrug resistance protein 1, bovine p-glycoprotein, CD243, CLCS, colchicin sensitivity, doxorubicin resistance, ecotropic viral integration site 32, Evi32, GP170, mdr, Mdr1, MDR1A, Mdr1b, Mdr3, mdr-3, multi-drug resistance 3, multidrug resistance p-glycoprotein, multidrug resistance protein 1, Multidrug resistance protein 1A, multidrug resistance protein 1B, Multidrug resistance protein 2, multidrug resistance protein 3, multidrug resistance protein MDR1, multiple drug resistant 1a, P glycoprotein 1, P glycoprotein 3, P-glycoprotein, P-glycoprotein 1, P-glycoprotein 2, P-glycoprotein 3, P-glycoprotein/multidrug resistance 1, Pgp, p-gp, PGP1, PGP2, PGY1, Pgy-1, Pgy1-1, PGY2, Pgy3, Pgy-3, Phospholipid transporter ABCB1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
170913, 18669, 18671, 24646, 5243

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot, Western Blot

Concentration:
1.61 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P06795, P08183, P21447

Gene Symbols:
ABCB1, Abcb1a, Abcb1b

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 590-689 of human P Glycoprotein (NP_0009182)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA590031

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Antigen:
PPT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppt1

Gene Alias:
3.1.2.22, 9530043G02Rik, AA960502, C77813, ceroid-palmitoyl-palmitoyl-protein thioesterase 1, CLN1, D4Ertd184e, INCL, Palmitoyl-protein hydrolase 1, palmitoyl-protein thioesterase, palmitoyl-protein thioesterase 1, palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile), PPT, Ppt1, PPT-1, QnpA-18851, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19063, 29411, 5538

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.96 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
O88531, P45479, P50897

Gene Symbols:
Ppt1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-306 of human PPT1 (NP_0003011)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA590032

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Antigen:
MEK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP2K2

Gene Alias:
AA589381, CFC4, Dual specificity mitogen-activated protein kinase kinase 2, ERK activator kinase 2, ERK kinase 2, FLJ26075, MAP kinase kinase 2, MAP kinase/Erk kinase, MAP2K1, MAP2K2, MAPK, MAPK/ERK kinase 1, MAPK/ERK kinase 2, MAPKK 1, MAPKK 2, MAPKK2, MEK 1, MEK 2, MEK-1, Mek2, MEK-2, mitogen activated protein kinase kinase 2, mitogen-activated protein kinase kinase 2, mitogen-activated protein kinase kinase 2, p45, MK2, MKK1, Mkk2, OTTHUMP00000165827, PRKMK1, PRKMK2, protein kinase, mitogen activated, kinase 2, p45

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26396, 5605, 58960

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.89 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P36506, P36507, Q63932

Gene Symbols:
MAP2K2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MEK2 (NP_1095871)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG