PIPA590443
CPEB3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA590443-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA590443 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
CPEB3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cpeb3
Gene Alias
4831444O18Rik, CPEB3, CPE-binding protein 3, CPE-BP3, cytoplasmic polyadenylation element binding protein 3, cytoplasmic polyadenylation element-binding protein 3, hCPEB-3, KIAA0940, mKIAA0940, RGD1564670
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
208922, 22849, 309510
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.9 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q7TN99, Q8NE35
Gene Symbols
Cpeb3
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human CPEB3 (NP_0557273)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TFSPQIGLAQ TQHHQQPPPP APAPQPAQPA QPPQAQPPQQ RRSPASPSQA PYAQRSAAAA YGHQPIMTSK PSSSSAVAAA AAAAAASSAS SSWNTHQSVN AAWSAPSNPW GGLQAGRDPR RAVGVGVGVG VGVPSPLNPI SPLKKPFSSN VIAPPKFPRA APLTSKSWME DNAFRTDNGN NLLPFQDRSR PYDTFNLHSL ENSLMDMIRT DHEPLKGKHY PPSGPPMSFA DIMWRNHFAG RMGINFHHPG T; Positive Samples: Mouse heart, Mouse kidney, Rat heart Sequence-specific RNA-binding protein which acts as a translational repressor in the basal unstimulated state but, following neuronal stimulation, acts as a translational activator
- In contrast to CPEB1, does not bind to the cytoplasmic polyadenylation element (CPE), a uridine-rich sequence element within the mRNA 3'-UTR, but binds to a U-rich loop within a stem-loop structure
- Required for the consolidation and maintenance of hippocampal-based long term memory
- In the basal state, binds to the mRNA 3'-UTR of the glutamate receptors GRIA2/GLUR2 mRNA and negatively regulates their translation
- Also represses the translation of DLG4, GRIN1, GRIN2A and GRIN2B
- When activated, acts as a translational activator of GRIA1 and GRIA2
- In the basal state, suppresses SUMO2 translation but activates it following neuronal stimulation
- Binds to the 3'-UTR of TRPV1 mRNA and represses TRPV1 translation which is required to maintain normal thermoception
- Binds actin mRNA, leading to actin translational repression in the basal state and to translational activation following neuronal stimulation
- Negatively regulates target mRNA levels by binding to TOB1 which recruits CNOT7/CAF1 to a ternary complex and this leads to target mRNA deadenylation and decay (PubMed:21336257)
- In addition to its role in translation, binds to and inhibits the transcriptional activation activity of STAT5B without affecting its dimerization or DNA-binding activity
- This, in turn, represses transcription of the STAT5B target gene EGFR which has been shown to play a role in enhancing learning and memory performance (PubMed:20639532)
- In contrast to CPEB1, CPEB2 and CPEB4, not required for cell cycle progression (PubMed:26398195)
- [UniProt]
Compare Similar Items
Show Difference
Antigen: CPEB3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Cpeb3
Gene Alias: 4831444O18Rik, CPEB3, CPE-binding protein 3, CPE-BP3, cytoplasmic polyadenylation element binding protein 3, cytoplasmic polyadenylation element-binding protein 3, hCPEB-3, KIAA0940, mKIAA0940, RGD1564670
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 208922, 22849, 309510
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.9 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q7TN99, Q8NE35
Gene Symbols: Cpeb3
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human CPEB3 (NP_0557273)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CPEB3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Cpeb3
Gene Alias:
4831444O18Rik, CPEB3, CPE-binding protein 3, CPE-BP3, cytoplasmic polyadenylation element binding protein 3, cytoplasmic polyadenylation element-binding protein 3, hCPEB-3, KIAA0940, mKIAA0940, RGD1564670
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
208922, 22849, 309510
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.9 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q7TN99, Q8NE35
Gene Symbols:
Cpeb3
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human CPEB3 (NP_0557273)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RPS6KB2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rps6kb2
Gene Alias: 70 kDa ribosomal protein S6 kinase 2, 70kDa, KLS, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6KB, p70 S6K-beta, p70(S6K)-beta, P70-beta, P70-beta-1, P70-beta-2, p70-S6K 2, P70S6K2, p70S6Kb, ribosomal protein S6 kinase B2, ribosomal protein S6 kinase beta-2, ribosomal protein S6 kinase, 70kD, polypeptide 2, ribosomal protein S6 kinase, 70kDa, polypeptide 2, ribosomal protein S6 kinase, polypeptide 2, RPS6KB2, S6 kinase 2, S6 kinase-related kinase, S6K2, S6K-beta, S6K-beta2, S6K-beta-2, serine/threonine-protein kinase 14 beta, serine/threonine-protein kinase 14B, SRK, STK14B
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 361696, 58988, 6199
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9UBS0, Q9Z1M4
Gene Symbols: Rps6kb2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human p70 S6 Kinase 2 (NP_0039432)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RPS6KB2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rps6kb2
Gene Alias:
70 kDa ribosomal protein S6 kinase 2, 70kDa, KLS, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6KB, p70 S6K-beta, p70(S6K)-beta, P70-beta, P70-beta-1, P70-beta-2, p70-S6K 2, P70S6K2, p70S6Kb, ribosomal protein S6 kinase B2, ribosomal protein S6 kinase beta-2, ribosomal protein S6 kinase, 70kD, polypeptide 2, ribosomal protein S6 kinase, 70kDa, polypeptide 2, ribosomal protein S6 kinase, polypeptide 2, RPS6KB2, S6 kinase 2, S6 kinase-related kinase, S6K2, S6K-beta, S6K-beta2, S6K-beta-2, serine/threonine-protein kinase 14 beta, serine/threonine-protein kinase 14B, SRK, STK14B
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
361696, 58988, 6199
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9UBS0, Q9Z1M4
Gene Symbols:
Rps6kb2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human p70 S6 Kinase 2 (NP_0039432)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SLC44A1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Slc44a1
Gene Alias: 2210409B22Rik, 4833416H08Rik, AW547365, CD92, CDW92, CDW92 antigen, choline transporter-like protein 1, CHTL1, Ctl1, Slc44a1, solute carrier family 44 (choline transporter), member 1, solute carrier family 44 member 1, solute carrier family 44, member 1, transporter-like protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100434, 23446, 85254
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.43 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q6X893, Q8VII6, Q8WWI5
Gene Symbols: Slc44a1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 55-210 of human SLC44A1 (NP_5368562)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
SLC44A1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Slc44a1
Gene Alias:
2210409B22Rik, 4833416H08Rik, AW547365, CD92, CDW92, CDW92 antigen, choline transporter-like protein 1, CHTL1, Ctl1, Slc44a1, solute carrier family 44 (choline transporter), member 1, solute carrier family 44 member 1, solute carrier family 44, member 1, transporter-like protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100434, 23446, 85254
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.43 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q6X893, Q8VII6, Q8WWI5
Gene Symbols:
Slc44a1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 55-210 of human SLC44A1 (NP_5368562)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: EDC4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EDC4
Gene Alias: Autoantigen Ge-1, autoantigen RCD8, autoantigen RCD-8, BC022641, Edc4, enhancer of mRNA decapping 4, enhancer of mRNA-decapping protein 4, fe26b05, GE1, Ge-1, HEDL5, HEDLS, Human enhancer of decapping large subunit, LRRG00115, Nrn1l, RCD8, RCD-8, RGD1309136, si:ch211-237c7.1, si:dkey-16n13.6, wu:fe26b05
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 234699, 23644
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.67 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q3UJB9, Q6P2E9
Gene Symbols: EDC4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 800-1100 of human EDC4 (NP_0551443)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
EDC4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EDC4
Gene Alias:
Autoantigen Ge-1, autoantigen RCD8, autoantigen RCD-8, BC022641, Edc4, enhancer of mRNA decapping 4, enhancer of mRNA-decapping protein 4, fe26b05, GE1, Ge-1, HEDL5, HEDLS, Human enhancer of decapping large subunit, LRRG00115, Nrn1l, RCD8, RCD-8, RGD1309136, si:ch211-237c7.1, si:dkey-16n13.6, wu:fe26b05
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
234699, 23644
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.67 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q3UJB9, Q6P2E9
Gene Symbols:
EDC4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 800-1100 of human EDC4 (NP_0551443)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG