PIPA590724

CD11b Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA590724-Each-of-1 In Stock ₹ 45,218.46

PIPA590724 - Each of 1

₹ 45,218.46

In Stock

Quantity

1

Base Price: ₹ 45,218.46

GST (18%): ₹ 8,139.323

Total Price: ₹ 53,357.783

Antigen

CD11b

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ITGAM

Gene Alias

antigen CD11b (p170), antigen CD11b (p170), macrophage antigen alpha polypeptide, CD11 antigen-like family member B, CD11b, CD11B (p170), CD11b/CD18, cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement component 3 receptor 3 subunit, complement component receptor 3 alpha-a, complement receptor type 3, CR3, CR-3 alpha chain, CR3A, F730045J24Rik, integrin alpha M, integrin alpha-M, integrin subunit alpha M, integrin, alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITGAM, Leukocyte adhesion receptor MO1, leukocyte integrin alpha-M chain, LOC100351865, Ly-40, MAC1, Mac-1, Mac-1 alpha, Mac-1 alpha (Mac1A), MAC-1 alpha subunit, MAC1A, Mac-1a, macrophage antigen alpha, macrophage antigen alpha polypeptide, MGC117044, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6, unnamed protein product

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16409, 25021, 3684

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.44 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

P05555, P11215

Gene Symbols

ITGAM

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 145-340 of CD11b/ITGAM (NP_0006232)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: PQEDSDIAFL IDGSGSIIPH DFRRMKEFVS TVMEQLKKSK TLFSLMQYSE EFRIHFTFKE FQNNPNPRSL VKPITQLLGR THTATGIRKV VRELFNITNG ARKNAFKILV VITDGEKFGD PLGYEDVIPE ADREGVIRYV IGVGDAFRSE KSRQELNTIA SKPPRDHVFQ VNNFEALKTI QNQLREKIFA IEGTQT Positive Samples: THP-1, Mouse spleen, Mouse lung; Cellular Location: Membrane, Single-pass type I membrane protein CD11b (integrin alpha-M, ITGAM, integrin alpha-X, ITGAX) is a 165 kDa adhesion molecule that associates non-covalently with integrin beta-2 (CD18)
  • The CD11b/CD18 heterodimeric complex is also known as integrin alpha-M beta-2, Mac-1, and CR3 (complement receptor 3)
  • CD11b is expressed on the surface of monocytes/macrophages, granulocytes, activated lymphocytes, a subset of NK cells, a subset of dendritic cells, and microglia in the brain
  • CD11b/CD18 functions as the receptor for ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), CD14, CD50, CD23, heparin, iC3b, fibrinogen, and Factor X -these adhesions are critical for cell-cell and cell-matrix interactions
  • CD11b is expressed on 8% of spleen cells, 44% of bone marrow cells, and less than 1% of thymocytes, and is commonly used as a microglial marker in nervous tissue
  • The expression of CD11b increases during monocyte maturation and expression levels vary on tissue macrophages
  • Further, peritoneal macrophages are reported to express higher levels of CD11b than splenic macrophages
  • Diseases associated with CD11b dysfunction include systemic lupus erythematosus 6 and ITGAM-related susceptibility to systemic lupus erythematosus.

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PIPA590724

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Antigen:
CD11b

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGAM

Gene Alias:
antigen CD11b (p170), antigen CD11b (p170), macrophage antigen alpha polypeptide, CD11 antigen-like family member B, CD11b, CD11B (p170), CD11b/CD18, cell surface glycoprotein MAC-1 alpha subunit, cell surface glycoprotein MAC-1 subunit alpha, complement component 3 receptor 3 subunit, complement component receptor 3 alpha-a, complement receptor type 3, CR3, CR-3 alpha chain, CR3A, F730045J24Rik, integrin alpha M, integrin alpha-M, integrin subunit alpha M, integrin, alpha M, integrin, alpha M (complement component 3 receptor 3 subunit), ITGAM, Leukocyte adhesion receptor MO1, leukocyte integrin alpha-M chain, LOC100351865, Ly-40, MAC1, Mac-1, Mac-1 alpha, Mac-1 alpha (Mac1A), MAC-1 alpha subunit, MAC1A, Mac-1a, macrophage antigen alpha, macrophage antigen alpha polypeptide, MGC117044, MO1A, Neutrophil adherence receptor, neutrophil adherence receptor alpha-M subunit, SLEB6, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16409, 25021, 3684

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.44 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P05555, P11215

Gene Symbols:
ITGAM

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 145-340 of CD11b/ITGAM (NP_0006232)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA590725

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Antigen:
Erc2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Erc2

Gene Alias:
6430531D06, CAST, CAST1, CAST1/ERC2, CAZ-associated structural protein, CAZ-associated structural protein 1, Cmbp, cytomatrix protein p110, D14Ertd171e, ELKS/RAB6-interacting/CAST family member 2, ELKS2alpha, ELKSL, ERC protein 2, ERC2, KIAA0378, SPBC110, Spc110

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
238988, 259269

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.44 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q6PH08, Q8K3M6

Gene Symbols:
Erc2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 770-850 of human ERC2 (NP_0563911)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA590726

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Antigen:
RAI14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAI14

Gene Alias:
1700008J19Rik, 1700020L11Rik, Ankycorbin, ankyrin repeat and coiled-coil structure-containing protein, DKFZp564G013, Kiaa1334, mKIAA1334, NORPEG, NORPEG-like protein, novel retinal pigment epithelial cell protein, p125, RAI13, Rai14, retinoic acid induced 14, retinoic acid-induced protein 14

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
294804, 75646

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.93 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q5U312, Q9EP71

Gene Symbols:
RAI14

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-600 of human RAI14 (NP_0563922)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA590730

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Antigen:
COPG2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Copg2

Gene Alias:
2-COP, AW227625, cb943, coat protein, nonclathrin, gamma-2-cop, coatomer protein complex subunit gamma 2, coatomer protein complex, subunit gamma 2, coatomer protein gamma2-COP, coatomer subunit gamma-2, copg, Copg2, copg2 protein, COPI coat complex subunit gamma 2, fi31b06, FLJ11781, gamma-2-coat protein, Gamma-2-COP, gamma2-cop, gamma-cop, LOC101789299, RGD1566215, si:ch211-285d14.8, testicular secretory protein Li 12, wu:fi31b06

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26958, 301742, 54160

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.41 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
D4ABY2, Q9QXK3, Q9UBF2

Gene Symbols:
Copg2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_0362653)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG