PIPA594946

CD18 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA594946-Each-of-1 In Stock ₹ 44,705.10

PIPA594946 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CD18

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ITGB2

Gene Alias

2E6, AI528527, antigen CD18, B-2 integrin, CD18, CD18 leukocyte adhesion molecule, CD18 subunit, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, complement receptor C3 subunit beta, integrin beta 2, integrin beta chain, beta 2, integrin beta-2, integrin subunit beta 2, integrin, beta 2, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), ITGB2, LAD, LCAMB, Leu-CAM receptor, leukocyte cell adhesion molecule CD18, leukocyte surface protein, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C, Lfa1, LFA-1, lymphocyte function associated antigen 1, MAC-1, Mac-1 beta, macrophage antigen 1 (mac-1) beta subunit), macrophage antigen-1 beta, MF17, MFI7

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3689

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.

P05107

Gene Symbols

ITGB2

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human CD18 (24-58aa, ECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPD).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • CD18 integrin beta 2 subunit is a 90 kDa type I transmembrane protein expressed on all leucocytes
  • CD18 can combine with integrin molecules CD11a-c to form heterodimers at the cell surface, and these heterodimers are known to participate in the process of cell adhesion as well as cell-surface mediated signaling
  • CD18 forms heterodimers with four types of CD11 molecule to constitute leukocyte (beta2) integrins: alphaLbeta2 (CD11a/CD18, LFA-1), alphaMbeta2 (CD11b/CD18, Mac-1, CR3), alphaXbeta2 (CD11c/CD18) and alphaDbeta2 (CD11d/CD18)
  • In most cases, the response mediated by the integrin is a composite of the functions of its individual subunits, and these integrins are essential for proper leukocyte migration, mediating intercellular contacts
  • Absence of CD18 leads to leukocyte adhesion deficiency-1, severe reduction of CD18 expression leads to the development of a psoriasiform skin disease
  • CD18 is also a target of Mannheimia (Pasteurella) haemolytica leukotoxin and is sufficient to mediate leukotoxin-mediated cytolysis
  • Defects in the CD18 gene are the cause of leukocyte adhesion deficiency type I (LAD1)
  • Two transcript variants encoding the CD18 protein have been identified.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA594946

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Antigen:
CD18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ITGB2

Gene Alias:
2E6, AI528527, antigen CD18, B-2 integrin, CD18, CD18 leukocyte adhesion molecule, CD18 subunit, cell surface adhesion glycoprotein (LFA-1/CR3/P150,959 beta subunit precursor), cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, complement component 3 receptor 3 and 4 subunit, complement receptor C3 beta-subunit, complement receptor C3 subunit beta, integrin beta 2, integrin beta chain, beta 2, integrin beta-2, integrin subunit beta 2, integrin, beta 2, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1, macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (antigen CD18 subunit (p95), lymphocyte function-associated antigen 1, integrin B2), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), ITGB2, LAD, LCAMB, Leu-CAM receptor, leukocyte cell adhesion molecule CD18, leukocyte surface protein, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C, Lfa1, LFA-1, lymphocyte function associated antigen 1, MAC-1, Mac-1 beta, macrophage antigen 1 (mac-1) beta subunit), macrophage antigen-1 beta, MF17, MFI7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3689

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P05107

Gene Symbols:
ITGB2

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human CD18 (24-58aa, ECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPD).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594947

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Antigen:
CCR6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCR6

Gene Alias:
BN-1, CC chemokine receptor 6, C-C chemokine receptor type 6, C-C CKR-6, C-C motif chemokine receptor 6, CC-CKR-6, CCR6, CCR-6, CD196, chemokine (C-C motif) receptor 6, chemokine (C-C) receptor 6, chemokine receptor-like 3, CKR6, CKRL3, CKR-L3, Cmkbr6, DCR2, DRY6, DRY-6, G protein-coupled receptor 29, GPR29, GPRCY4, GPR-CY4, G-protein coupled receptor 29, KY411, LARC receptor, seven-transmembrane receptor, lymphocyte, 22, STRL22

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1235, 12458, 308163

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O54689, P51684

Gene Symbols:
CCR6

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human CCR6 (358-374aa RQTSETADNDNASSFTM).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594948

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Antigen:
CHK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11200, 114212, 50883

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
O96017, Q9Z265

Gene Symbols:
Chek2

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Chk2 (427-441aa FSEHRTQVSLKDQIT).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA594949

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Antigen:
HRH3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HRH3

Gene Alias:
AW049250, G protein-coupled receptor, G protein-coupled receptor 97, GPCR97, G-protein coupled receptor 97, H3R, HH3R, histamine H3 receptor, histamine H3 receptor H3L isoform, histamine H3 receptor H3S isoform, histamine receptor, histamine receptor H 3, histamine receptor H3, Hrh3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11255, 85268, 99296

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide, 0.05MG thimerosal

Gene Accession No.:
P58406, Q9QYN8, Q9Y5N1

Gene Symbols:
HRH3

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human HRH3 (428-445aa CPQKLKIQPHSSLEHCWK).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG