PIPA594921

CD30 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA594921-Each-of-1 In Stock ₹ 44,705.10

PIPA594921 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CD30

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNFRSF8

Gene Alias

Ber-H2, Cd30, CD30 antigen, CD30 molecule, CD30L receptor, cytokine receptor CD30, D1S166E, Ki, Ki-1, Ki-1 antigen, Lymphocyte activation antigen CD30, sCD30, soluble CD30, TNF receptor superfamily member 8, TNFRSF8, Tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8, Tumor necrosis factor superfamily member 8, tumor necrosis factor superfamily, member CD30

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

943

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

P28908

Gene Symbols

TNFRSF8

Immunogen

E.coli-derived human CD30 recombinant protein (Position: T322-K595).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Human CD30 shares 60% and 57% amino acid (aa) sequences identity with mouse and rat CD30, respectively
  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • CD30 (Ki-1, TNF Receptor Superfamily Member 8) is a type I transmembrane glycoprotein of the TNF receptor superfamily
  • CD30 was originally identified as a cell surface antigen of Hodgkins and Reed-Sternberg cells using monoclonal antibody Ki-1
  • The ligand for CD30 is CD30L (CD153)
  • The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death
  • CD30 has a critical role in the pathophysiology of Hodgkin's disease and other CD30+ lymphomas
  • CD30 acts as a costimulatory molecule in thymic negative selection
  • In addition to its expression on Hodgkin's and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin's lymphomas (including Burkitt's lymphomas), virus-infected T and B cells, and on normal T and B cells after activation
  • In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that co-express CD45RO and the IL4 receptor
  • Soluble form of CD30 (sCD30) serves as a marker reflecting Th2 immune response
  • TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB
  • CD30 is a positive regulator of apoptosis, and has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity
  • Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported
  • CD30 is expressed by mononuclear cells in Hodgkin's lymphoma, Reed Sternberg cells and most Anaplastic Large Cell Lymphomas (ALCL)
  • CD30 is also expressed by embryonal carcinomas.

Compare Similar Items

Show Difference

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PIPA594921

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Antigen:
CD30

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNFRSF8

Gene Alias:
Ber-H2, Cd30, CD30 antigen, CD30 molecule, CD30L receptor, cytokine receptor CD30, D1S166E, Ki, Ki-1, Ki-1 antigen, Lymphocyte activation antigen CD30, sCD30, soluble CD30, TNF receptor superfamily member 8, TNFRSF8, Tumor necrosis factor receptor superfamily member 8, tumor necrosis factor receptor superfamily, member 8, Tumor necrosis factor superfamily member 8, tumor necrosis factor superfamily, member CD30

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
943

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P28908

Gene Symbols:
TNFRSF8

Immunogen:
E.coli-derived human CD30 recombinant protein (Position: T322-K595).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA594922

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Antigen:
ATM

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATM

Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
472

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q13315

Gene Symbols:
ATM

Immunogen:
E.coli-derived human ATM recombinant protein (Position: D2870-V3056).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA594924

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Antigen:
Claudin 5

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CLDN5

Gene Alias:
AI854493, AWAL, BEC1, Brain endothelial cell clone 1 protein, claudin 5, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome), claudin-5, claudin-5 protein, Cldn5, CPETRL1, lung-specific membrane protein, MBEC1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome, Unknown (protein for MGC:138054)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
65131, 7122

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
O00501, Q9JKD6

Gene Symbols:
CLDN5

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5 (191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA594925

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Antigen:
MBD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mbd2

Gene Alias:
demethylase, DKFZp586O0821, DMTase, MBD2, MBD2a, methyl-CpG binding domain protein 2, methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, NY-CO-41

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8932

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q9UBB5

Gene Symbols:
Mbd2

Immunogen:
E.coli-derived human MBD2 recombinant protein (Position: W159-A411).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG