PIPA594922
ATM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA594922-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA594922 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ATM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Lyophilized
Applications
Western Blot
Concentration
500 μg/mL
Formulation
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
E.coli-derived human ATM recombinant protein (Position: D2870-V3056).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Human ATM shares 95% amino acid (aa) sequence identity with mouse ATM
- Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: ATM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 472
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: E.coli-derived human ATM recombinant protein (Position: D2870-V3056).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
472
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
E.coli-derived human ATM recombinant protein (Position: D2870-V3056).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Claudin 5
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CLDN5
Gene Alias: AI854493, AWAL, BEC1, Brain endothelial cell clone 1 protein, claudin 5, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome), claudin-5, claudin-5 protein, Cldn5, CPETRL1, lung-specific membrane protein, MBEC1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome, Unknown (protein for MGC:138054)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 65131, 7122
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.: O00501, Q9JKD6
Gene Symbols: CLDN5
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5 (191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Claudin 5
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CLDN5
Gene Alias:
AI854493, AWAL, BEC1, Brain endothelial cell clone 1 protein, claudin 5, claudin 5 (transmembrane protein deleted in velocardiofacial syndrome), claudin-5, claudin-5 protein, Cldn5, CPETRL1, lung-specific membrane protein, MBEC1, TMDVCF, TMVCF, Transmembrane protein deleted in VCFS, transmembrane protein deleted in velocardiofacial syndrome, Unknown (protein for MGC:138054)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
65131, 7122
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide
Gene Accession No.:
O00501, Q9JKD6
Gene Symbols:
CLDN5
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Claudin 5 (191-218aa RPDLSFPVKYSAPRRPTATGDYDKKNYV).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MBD2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mbd2
Gene Alias: demethylase, DKFZp586O0821, DMTase, MBD2, MBD2a, methyl-CpG binding domain protein 2, methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, NY-CO-41
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8932
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: Q9UBB5
Gene Symbols: Mbd2
Immunogen: E.coli-derived human MBD2 recombinant protein (Position: W159-A411).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MBD2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mbd2
Gene Alias:
demethylase, DKFZp586O0821, DMTase, MBD2, MBD2a, methyl-CpG binding domain protein 2, methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2, NY-CO-41
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8932
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
Q9UBB5
Gene Symbols:
Mbd2
Immunogen:
E.coli-derived human MBD2 recombinant protein (Position: W159-A411).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Osteopontin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SPP1
Gene Alias: 2AR, 2b7, 44 kDa bone phosphoprotein, Apl-1, BNSP, Bone sialoprotein 1, Bone sialoprotein 1 (BSPI/BSP1), Bsp, BSPI, Calcium oxalate crystal growth inhibitor protein, CALPHA1 fusion, Early T lymphocyte activation 1 (ETA1), early T-lymphocyte activation 1, early T-lymphocyte activation 1 protein, Eta, ETA-1, HGNC:11255, immunoglobulin alpha 1 heavy chain constant region fusion protein, MGC110940, Minopontin, nephropontin, Op, Opn, Opnl, OSP, osteopontin, osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein, osteopontin-like protein, PSEC0156, Ric, Secreted phosphoprotein 1, secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1), secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1), Secreted phosphoprotein 1 (SPP1), secreted phosphoprotein 1 variant 6, Sialoprotein (osteopontin), SPP1, SPP-1, SPP1/CALPHA1 fusion, unnamed protein product, urinar, urinary stone protein, Uropontin
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20750, 25353, 6696
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Lyophilized
Applications: ELISA, Western Blot
Concentration: 500 μg/mL
Formulation: PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.: P08721, P10451, P10923
Gene Symbols: SPP1
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Osteopontin (281-314aa HEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Osteopontin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SPP1
Gene Alias:
2AR, 2b7, 44 kDa bone phosphoprotein, Apl-1, BNSP, Bone sialoprotein 1, Bone sialoprotein 1 (BSPI/BSP1), Bsp, BSPI, Calcium oxalate crystal growth inhibitor protein, CALPHA1 fusion, Early T lymphocyte activation 1 (ETA1), early T-lymphocyte activation 1, early T-lymphocyte activation 1 protein, Eta, ETA-1, HGNC:11255, immunoglobulin alpha 1 heavy chain constant region fusion protein, MGC110940, Minopontin, nephropontin, Op, Opn, Opnl, OSP, osteopontin, osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein, osteopontin-like protein, PSEC0156, Ric, Secreted phosphoprotein 1, secreted phosphoprotein 1 (osteopontin bone sialoprotein I early T lymphocyte activation 1), secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1), Secreted phosphoprotein 1 (SPP1), secreted phosphoprotein 1 variant 6, Sialoprotein (osteopontin), SPP1, SPP-1, SPP1/CALPHA1 fusion, unnamed protein product, urinar, urinary stone protein, Uropontin
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20750, 25353, 6696
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Lyophilized
Applications:
ELISA, Western Blot
Concentration:
500 μg/mL
Formulation:
PBS with 5MG BSA and 0.05MG sodium azide
Gene Accession No.:
P08721, P10451, P10923
Gene Symbols:
SPP1
Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Osteopontin (281-314aa HEDMLVVDPKSKEEDKHLKFRISHELDSASSEVN).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG