PIPA595534

AES Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595534-Each-of-1 In Stock ₹ 45,646.26

PIPA595534 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

AES

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TLE5

Gene Alias

Aes, AES-1, AES-2, AL024115, Amino enhancer of split, amino-terminal enhancer of split, Esp1, gp130-associated protein GAM, Grg, Grg5, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, related to Drosophila groucho, R-esp1, TLE family member 5, TLE family member 5, transcriptional modulator, TLE family member 5, amino-terminal enhancer of split, TLE5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

166

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.

Q08117

Gene Symbols

AES, TLE5

Immunogen

E.coli-derived human AES recombinant protein (Position: Y69-L138).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Adhesion to extracellular matrix regulates cell survival through both integrin engagement and appropriate cell spreading
  • Anoikis is the molecular mechanism of apop-tosis induced by integrin detachment
  • Amino-terminal enhancer of split (AES) is a member of the Groucho/ transducin-like enhancer of split (TLE) family of transcriptional regulators, a group of transcriptional co-repressors that play important roles in neurogenesis, segmentation, and sex determination
  • AES forms a complex with Bit1 (Bcl-2 inhibitor of transcription 1), a mitochondrial protein that is released into the cytoplasm upon onset of apoptosis
  • It has been suggested that this complex turns off a survival-promoting gene transcription program controlled by the TLE protein family
  • Interestingly, apoptosis of cells transfected with AES and Bit1 could be inhibited if the cells were allowed to attach to fibronectin through the alpha5beta1 integrin suggesting that the Bit1-AES pathway contributing to anoikis is regulated by integrins, and in particular, the alpha5beta1 integrin.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA595534

--


Antigen:
AES

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TLE5

Gene Alias:
Aes, AES-1, AES-2, AL024115, Amino enhancer of split, amino-terminal enhancer of split, Esp1, gp130-associated protein GAM, Grg, Grg5, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, related to Drosophila groucho, R-esp1, TLE family member 5, TLE family member 5, transcriptional modulator, TLE family member 5, amino-terminal enhancer of split, TLE5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
166

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q08117

Gene Symbols:
AES, TLE5

Immunogen:
E.coli-derived human AES recombinant protein (Position: Y69-L138).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA595536

--


Antigen:
CACNA2D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CACNA2D2

Gene Alias:
a2d2, alpha 2 delta calcium channel subunit, CACNA2D, Cacna2d2, calcium channel, voltage dependent, alpha2/delta subunit 2, calcium channel, voltage-dependent, alpha 2/delta subunit 2, calcium voltage-gated channel auxiliary subunit alpha2delta 2, Cav alpha2/delta2, du, ducky, gene 26, KIAA0558, mKIAA0558, Protein ducky, td, torpid, Voltage-dependent calcium channel subunit alpha-2/delta-2, Voltage-dependent calcium channel subunit alpha-2-2, Voltage-dependent calcium channel subunit delta-2, Voltage-gated calcium channel subunit alpha-2/delta-2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
300992, 56808, 9254

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
Q6PHS9, Q8CFG6, Q9NY47

Gene Symbols:
CACNA2D2

Immunogen:
E.coli-derived human CACNA2D2 recombinant protein (Position: Q66-Q284).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA595537

--


Antigen:
Caspase 2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP2

Gene Alias:
CASP2, CASP-2, caspase 2, caspase 2 apoptosis-related cysteine peptidase, caspase-2, Caspase-2 subunit p12, Caspase-2 subunit p13, Caspase-2 subunit p18, ICH1, ICH-1, ICH-1 protease, ICH-1L, ICH-1L/1S, NEDD2, NEDD-2, Neural precursor cell expressed developmentally down-regulated protein 2, PPP1R57, Protease ICH-1, protein phosphatase 1, regulatory subunit 57

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12366, 64314, 835

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P29594, P42575, P55215

Gene Symbols:
CASP2

Immunogen:
E.coli-derived human Caspase-2 recombinant protein (Position: G170-T325).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595538

--


Antigen:
CCL6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccl6

Gene Alias:
c10, CC chemokine C10, C-C motif chemokine 6, Ccl6, CCL6(22-95), CCL6(23-95), chemokine (C-C motif) ligand 6, chemokine ligand 6, Mrp-1, Protein C10, Scay6, Scya6, small inducible cytokine A6, small-inducible cytokine A6

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20305, 287910

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and 0.05MG sodium azide

Gene Accession No.:
P27784, Q68FP3

Gene Symbols:
Ccl6

Immunogen:
E.coli-derived mouse CCL6 recombinant protein (Position: G22-A116).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG