PIPA595194

TSC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA595194-Each-of-1 In Stock ₹ 44,362.86

PIPA595194 - Each of 1

₹ 44,362.86

In Stock

Quantity

1

Base Price: ₹ 44,362.86

GST (18%): ₹ 7,985.315

Total Price: ₹ 52,348.175

Antigen

TSC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TSC2

Gene Alias

LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22084, 24855, 7249

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

P49815, P49816, Q61037

Gene Symbols

TSC2

Immunogen

E.coli-derived human Tuberin recombinant protein (Position: H1611-V1807).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Human Tuberin shares 94% and 90% amino acid (aa) sequences identity with mouse and rat Tuberin, respectively
  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
  • Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
  • TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
  • Interaction between TSC1 and TSC2 may facilitate vesicular docking
  • TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
  • Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
  • Alternative splicing results in transcript variants of three different isoforms of TSC2.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595194

--


Antigen:
TSC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM, Nafld, OTTHUMP00000198394, PPP1R160, protein phosphatase 1, regulatory subunit 160, Rc, renal carcinoma, Tcs2, Tsc2, TSC4, Tuberin, tuberous sclerosis 2, tuberous sclerosis 2 homolog protein, tuberous sclerosis 2 protein, Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 24855, 7249

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P49815, P49816, Q61037

Gene Symbols:
TSC2

Immunogen:
E.coli-derived human Tuberin recombinant protein (Position: H1611-V1807).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595195

--


Antigen:
Ubiquitin B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBB

Gene Alias:
AL033289, epididymis secretory protein Li 50, HEL-S-50, HUBCEP52, im:6892314, im:6892314 protein, MGC127041, polyubiquitin, polyubiquitin B, polyubiquitin-B, RPL40, Rps27a, si:ch211-202a12.3, Uba52, Ubb, Ubb2, UBC, Ubi-p63E, Ubiquitin, ubiquitin B, ubiquitin C, Ubiquitin-related, zgc:172187, zUBC

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
192255, 22187, 7314

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P0CG47, P0CG49, P0CG51

Gene Symbols:
UBB

Immunogen:
E.coli-derived human Ubiquitin recombinant protein (Position: M77-G152).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595197

--


Antigen:
BMI-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BMI1

Gene Alias:
AW546694, B lymphoma Mo-MLV insertion region 1, B lymphoma Mo-MLV insertion region 1 homolog, Bmi1, Bmi-1, BMI1 polycomb ring finger oncogene, BMI1 polycomb ring finger proto-oncogene, BMI1 proto-oncogene, polycomb ring finger, FLVI2/BMI1, flvi-2/bmi-1, murine leukemia viral (bmi-1) oncogene homolog, Pcgf4, Pcgf4 antibody, Polycomb complex protein BMI-1, polycomb group protein Bmi1, polycomb group ring finger 4, polycomb group RING finger protein 4, RING finger protein 51, RNF51, RP11-573G6.1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12151, 307151, 648

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P25916, P35226

Gene Symbols:
BMI1

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Bmi1 (135-165aa IEFFDQNRLDRKVNKDKEKSKEEVNDKRYLR).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595198

--


Antigen:
NFkB p52/p100

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nfkb2

Gene Alias:
CVID10, DNA-binding factor KBF2, H2TF1, Lymphocyte translocation chromosome 10 protein, lyt, LYT10, LYT-10, NF kappaB2, NF KB, NF-kappaB2, nfkb p100, NFKB, p52/p100 subunit, NFKB2, NF-kB2, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit 2, nuclear factor Kappa-B, subunit 2, nuclear factor NF-kappa-B p100 subunit, Nuclear factor NF-kappa-B p52 subunit, nuclear factor of Kappa light chain gene enhancer in B cells 2, nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100), nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100, oncogene Lyt-10, p100, p49, p49/p100, p50B, p52, RGD1307189, transcription factor NFKB2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18034, 309452, 4791

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q00653, Q9WTK5

Gene Symbols:
Nfkb2

Immunogen:
E.coli-derived human NFkB p100/p52 recombinant protein (Position: M1-R340).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG